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ANS- PNS, SNS differences & functions
Question | Answer |
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Sympathetic system has a broader distribution, innervating effectors throughout the body | SNS fibers= ramification. SNS pregang fibers may traverse many ganglia bf terminiating post-gangl cell. Synaptic arborization = single preganglionic fiber terminating on many post-ganglionic cells. = the basis for the diffuse nature of SNS response. |
Parasympathetic system is relatively limited | The PNS has its terminal ganglia near the end-organ. Sometimes 1:1 ratio relationship between pre-end post-ganglionic fibers. The ratio between preganglionic vagal fibers and ganglion cells may be much higher, e.g. 1:8000 for Auerbach's plexus. |
SNS anatomy | Cell bodies of preganglionic fibers: found in intermediolateral columns of the spinal cord (first thoracic to second or third lumbar segments |
SNS anatomy | Preganglionic fiber axons synapse with sympathetic ganglionic neurons which lie outside the cerebrospinal axis. Sympathetic ganglia are found at three sites: Paravertebral, Prevertebral, Terminal |
SNS Paraverebral ganglia- | 22 interconnected pairs on either sides of the vertebral column. (para: Gr: at the side of along side)- Myelinated preganglionic fibers (white rami: thoracolumbar outflow only) leave through the anterior spinal roots. |
SNS Paraverebral ganglia- | Postganglionic fibers (gray rami) runs back to spinal nerves for distribution to: blood vessesls of the skin , blood vessels of skeletal muscle, sweat glands, pilomotor muscles |
Prevertebral Ganglia: abdominal and pelvic location, comprised of: | - celiac ganglia -superior mesenteric ganglia - aorticorenal and inferior mesenteric ganglia |
SNS Post ganglia fibers- | All postganglionic fibers arise from cell bodies located within these ganglia; the preganglionic fibers come from upper thoracic segments: No sympathetic preganglionic fibers come from above the first thoracic level |
Terminal Ganglia: few, residing near the innervated organ, including | 1) ganglia associated with the urinary bladder and rectum 2) cervical ganglia (neck): three ganglia (chain) mediating vasomotor, secretory, pupillodilatory and pilomotor responses of the head and neck) |
Adrenal medulla (top of kidney) is similar to sympathetic ganglia. | Difference: a) Epinephrine is released (post-ganglionic sympathetic fibers release norepinephrine) b) Chromaffin cells are innerved by preganglionic fibers that release acetylcholine. |
PNS Cranial-Sacral outflow 1) Midbrain | Long Pregang fibers target Cilary ganglion of the orbit |
PNS Cranial-Sacral outflow 2) Medulla Oblongata | Long preganglionic fibers- CNs - 7, 9, 10 7- submax, sublingual and sphenopalatine 9- otic 10- many thoracic and visceral ganglia |
PNS Cranial-Sacral outflow 3) Sacral | Long pregang fibers- terminate in or near bladder, rectum and sex organs |
PNS | Long Pre-ganglionic Fibers, Short Post "Para= Long Pre" Pre to Post= Ach/Nicotinic Post to Site=Ach/nicotinic/muscarinic |
SNS | Short Pre- long Post "Have sympathy that the Post-age took so Long" Pre to Post=ach/nicotinic Post to Site=Norepin/ a, b1, b2 receptors |
Adrenal | Nerve to Adrenal gland= Ach/nicotinic on adrenal gland= epinepherine (80%), Norepin (20%) |
Somatic | Nerve to terminal skeletal muscle= ach/nicotinic |