In each blank, try to type in the
word that is missing. If you've
typed in the correct word, the
blank will turn green.
If your not sure what answer should be entered, press the space bar and the next missing letter will be displayed. When you are all done, you should look back over all your answers and review the ones in red. These ones in red are the ones which you needed help on. Class: K+ Sparing Diuretic/Thiazide ComboBrand: (capsule); Maxzide (tablet)Generic: /
Hydrochlorothiazide
Indications: HTN,
Edema
Dose Forms: Tablet (Maxzide): 37.5/25 or 75/50mg
Capsule (Dyazide): 37.5/25 or 50/25mg
Route: OralAdult/Ped. Dosing: Triamterene: 37.5-75mg
QD
HCTZ: 25-50mg QD
Ped:N/AMOA: Triamterene: K+ sparing diuretic that inhibits reabsorption of Na+ exchange for K+ and H+ by exerting a direct effect on the distal renal tubule
Class: DiureticBrand: LasixGeneric: FurosemideIndications: HTN, Dose Forms: :
20, 40, 80mg
IV/IM Soln.: 10mg/ml
Oral Soln.: 10mg/ml or 40mg/5ml
Route: Oral, IV, IMAdult/Ped. Dosing: 20-80mg
TID-QID
Ped:
1-2mg/kg/day MOA: Anthanilic acid derivative and a potent diuretic that works by blocking the absorption of Na+ and Cl- in the kidney tubules, causing a profound increase in urine output Class: ACE /
Thiazide Combo
Brand: Prinzide; ZestoreticGeneric: Lisinopril/
Hydrochlorothiazide
Indications: HTNDose Forms: Tablets:
Prinzide: 10/12.5 or 20/25 mg
Zestoretic: 10/12.5, 20/12.5, 20/25mg
Route: OralAdult/Ped. Dosing: 10/6.25 – 80/50mg
QD
Ped:N/AMOA: diuretic and an antihypertensive agent that elevated blood pressure; ACE inhibitor Class: ACE Inhibitor/
Ca2+ Channel Blocker
Brand: Generic: /
Benazepril
Indications: HTNDose Forms: Capsules:
2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40mg
Route: OralAdult/Ped. Dosing: 2.5/10-10/40mg
QD
Ped:N/AMOA: Amlodipine: dihydropyridine Ca2+ channel blocker
Benazepril: nonsulfhydryl ACE inhibitor
Class: Beta-Adrenergic Blocker/Thiazide Combo; CardioselectiveBrand: Tenoretic
Generic: Atenolol/
Chlorthalidone
Indications: HTNDose Forms: Tablets:
50/25 or 100/25mg
Route: Adult/Ped. Dosing: 50/25-100/25mg :N/AMOA: Atenolol: beta-blocking agent
Chlorthalidone: diuretic acting on the cortical diluting segment of the ascending limb of the loop of Henle; increase excretion of Na+ and Cl-
Class: ; Factor Xa inhibitorBrand: XareltoGeneric: RivaroxibanIndications: Deep Vein Thrombosis, Pulmonary embolism, Prophylaxis, Nonvalvular atrial fibrillationDose Forms: Tablets:
10, 15, 20 mg
Route: OralAdult/Ped. Dosing: 10-20mg
QD-BID
Ped:N/AMOA: Rivaroxaban selectively inhibits factor Xa without the need of a cofactor (eg, anti-thrombin III) for activity. Class: Anticoagulant; Low Molecular Weight HeparinBrand: Generic: EnoxaparinIndications: Deep Vein Thrombosis, Prophylaxis, MIDose Forms: Inj. Soln.:
30mg/0.3ml, 40/0.4, 60/0.6, 80/0.8, 100mg/ml, 120/0.8, 150mg/ml
Route: SubQAdult/Ped. Dosing: 0.75-1.5mg/kg QD
(30-150mg per dose)
Ped: 0.5-1.5mg/kg every 12 hoursMOA: Low molecular weight heparin with anti-Factor Xa and anti-thrombin activities Class: Anticoagulant; Thrombin InhibitorBrand: PradaxaGeneric: DabigatranIndications: Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary EmbolismDose Forms: Capsules:
75 or 150mg
Route: Adult/Ped. Dosing: 150mg :N/AMOA: Competitive, direct thrombin inhibitor which prevents thrombus development. It inhibits both free & clot-bound thrombin as well as thrombin-induced platelet aggregation Class: AnticoagulantBrand: Coumadin; JantovenGeneric: WarfarinIndications: Atrial Fibrillation, Prophylaxis, Prosthetic Cardiac Valve, Thrombosis, Pulmonary EmbolismDose Forms: Tablets:
1, 2, 2.5, 3, 4, 5, 6, 7.5, 10mg
IV Powder for Soln. (Coumadin only): 5mg
Route: Oral, Adult/Ped. Dosing: 1-10mg :N/AMOA: Blocks the regeneration of vitamin K epoxide, thus inhibiting synthesis of vitamin K-dependent clotting factors (2, 7, 9 and 10) and the anticoagulant proteins C and S Class: ADP-Induced Aggregation Inhibitor;
Platelet Aggregation Inhibitor
Brand: PlavixGeneric: Indications: Prophylaxis, Dose Forms: Tablets:
75 or 300mg
Route: OralAdult/Ped. Dosing: 75mg
QD
Ped:N/AMOA: Anticoagulant; prodrug that inhibits platelet aggregation by selectively & irreversibly binding to the ADP P2Y12 receptor on platelets Class: Parenteral Electrolyte
(K+ Supplement)
Brand: K-Dur; K-Tab; Klor-ConGeneric: PotassiumIndications: Hypokalemia, Dose Forms: K-Dur:
20 mEq ER tablet
K-Tab:
10 mEq ER tablet
Klor-Con:
20 or 25 mEq oral for soln.,
8, 10, M10, M20
ER tabs
Route: Oral, IVAdult/Ped. Dosing: 10-100 mEq once to five times daily
Ped: Oral:
3-8 mEq/kg/day
IV:
0.5-0.75 mEq/kg over 1-2 hrs
MOA: Electrolyte replenisher that aids in many physiological processes Class: CNS Agent; Immune SuppressantBrand: Generic: acetateIndications: Relapsing remitting Multiple SclerosisDose Forms: Inj. Soln.:
20mg/ml
Route: SubQAdult/Ped. Dosing: 20mg
QD
Ped:N/AMOA: Believed to modify immune processes or functions which are thought to be liable for MS pathogenesis. In vitro studies suggest that glatiramer specific suppressor T-cells are induced & activated in the periphery Class: Colony Stimulating Factor; HematopoieticBrand: NeulastaGeneric: Indications: Febrile neutropenia in patients with non-myeloid , ProphylaxisDose Forms: Inj. Soln.: 6mg/0.6mlRoute: SubQAdult/Ped. Dosing: 6mg
once per chemo cycle
(don’t administer between 14 days prior to & 24 hrs after admin of chemo)
Ped:N/AMOA: A colony stimulating factor that acts on hematopoietic cells by binding to specific cell surface receptors thereby stimulating proliferation, differentiation, commitment, and end cell functional actv’n Class: Antineoplastic Agent; Monoclonal AntibodyBrand: RituxanGeneric: RituximabIndications: Non-Hodgkins lymphoma, Rheumatoid Arthritis, Chronic Lymphoid LeukemiaDose Forms: Inj. Soln.: /ml
Route: IVAdult/Ped. Dosing: 375mg/m(2), usually given as part of a scheduled regiment with other meds
Ped:N/AMOA: MAB that binds to antigen CD20, this disrupts the cell cycle of B-cells resulting in cell lysis and even apoptosis Class: Aldosterone Receptor Antagonist; K+ Sparing DiureticBrand: AldactoneGeneric: SpironolactoneIndications: HTN, Hypokalemia, Ascites, Edema, AldoseronismDose Forms: :
25, 50, 100mg
Route: OralAdult/Ped. Dosing: 25-400mg
QD
Ped:N/A
MOA: Renal competitive aldosterone antagonist; it inhibits the effect of aldosterone by competing for the aldosterone-dependent Na+/K+ exchange site in the distal tubule cells. This increases the secretion of H2O & Na+, while decreasing the excretion of K+ Class: ARB/Thiazide Brand: AvalideGeneric: Irbesartan/
Hydrochlorothiazide
Indications: HTNDose Forms: Tablets:
150/12.5, 300/12.5, 300/25
Route: OralAdult/Ped. Dosing: 150/12.5-300/25mg
QD
Ped:N/AMOA: ‘sartan: angiotensin II blocker
HCTZ: increases excretion of Na+ & Cl- (diuretic/antihypertensive)
Class: ARB/Thiazide ComboBrand: Benicar HCTGeneric: Olmesartan/
Hydrochlorothiazide
Indications: HTNDose Forms: :
20/12.5, 40/12.5, 40/25mg
Route: OralAdult/Ped. Dosing: 20/12.5-40/25mg
QD
Ped:N/AMOA: ‘sartan: angiotensin II blocker
HCTZ: increases excretion of Na+ & Cl- (diuretic/antihypertensive)
Class: ARB/Thiazide ComboBrand: Diovan HCTGeneric: /
Hydrochlorothiazide
Indications: HTNDose Forms: Tablets:
80/12.5, 160/12.5, 160/25, 320/12.5, 320/25mg
Route: OralAdult/Ped. Dosing: 160/12.5-320/25mg
QD
Ped:N/AMOA: ‘sartan: angiotensin II blocker
HCTZ: increases excretion of Na+ & Cl- (diuretic/antihypertensive)
Class: ARB/Thiazide ComboBrand: HyzaarGeneric: Losartan/
Hydrochlorothiazide
Indications: HTN,
Prophylaxis
Dose Forms: Tablets:
50/12.5, 100/12.5, 100/25mg
Route: OralAdult/Ped. Dosing: 50/12.5-100/25mg :N/AMOA: ‘sartan: angiotensin II : increases excretion of Na+ & Cl- (diuretic/antihypertensive)
Class: Diuretic; Brand: HCTZGeneric: HydrochlorothiazideIndications: HTN,
Edema
Dose Forms: Tablets: 12.5, 25, 50mg
Capsule: 12.5mg
Route: OralAdult/Ped. Dosing: 12.5-100mg QD
(can be divided)
Ped: 1-2mg/kg/day MOA: Electrolyte reabsorption inhibitor (resulting in increased excretion of Na+ and Cl- in equal amounts) |
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