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SGU: Nucleic Acids Quiz

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1. What is the function of guanine-7-methyl transferase?




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2. What does non-overlapping genetic code mean?




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3. What nucleotide is acyclovir an anologue of?




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4. What is the function of SSB proteins?




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5. What is the function of PAP?




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6. In what direction does DNA poly read DNA?




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7. Explain how Rifamycin targets and inhibits specfic components of transcription.




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8. What nucleoside triphosphate is involved in carbohydrate biosynthesis?




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9. What happens to DNA with a lot of methyl groups?




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10. How are Okazaki fragments joined together?




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11. Changes A to I in glutamate receptor to change glutamine to arginine in brain




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12. Histones are rich in lysine and arginine, and as a result carry a positive charge. This makes it easier for negatively charged chromatin to associate.




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13. helps cell distinguish between different RNA, plays a role in regulation of mRNA processing, transport, and translation




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14. a tRNA with its amino acid group




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15. prokaryotic:polycistronic, translation and transcription together, internal AUG sites used




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16. AUG




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17. doesn't have one




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18. nitrogenous base (attached to 1’ C by B-N-glycosidic bond), a ribose sugar (OH at 2’ C), and a phosphate group (backbone of DNA, attached to 5’ C) – present in RNA molecules




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19. Inhibits peptidyl transferase/blocks elongation




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20. Topoisomerase I: forms a single covalent bond with the DNA and breaks phosphodiester bond to allow free rotation





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