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USMLE Step 1

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Drug
MOA & ADRs
Adrenergic receptor: Alpha-1   show
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show inhibits adenylate cyclase, yielding low cAMP, cause decreased NE release, also decreases insulin release  
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Adrenergic receptor: Beta-1   show
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show causes vasodilation, a small decrease in total peripheral resistance, bronchodilation, increased gluconeogenesis, increases glycogen release and relaxes the uterus  
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Dopamine receptor: D1   show
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show causes decreased NE release  
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show MOA: non-selective alpha-blocker used in HPTN crisis & dx of pheochromocytoma; ADRs: orthohypoTN, reflex tachy, vertigo & decreased ejaculation  
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Prazosin   show
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Terazosin   show
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Clonidine   show
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Beta-blockers   show
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Terbutaline   show
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Albuterol   show
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Dopamine   show
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show MOA: prevents NE & dopamine from getting packaged into vesicles, then degraded by MAO & thus no extra-cellular effect, used for HPTN  
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show MOA: similar to reserpine, but also blocks NE release of any NE already in vesicular stores, used for HPTN; ADRs: decreased male sexual fx & orthostatic hypoTN  
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