Pharmacokinetics
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| show | The biotransformation of medications
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| show | in the liver
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| What is the most important group of enzymes for drug metabolism? | show 🗑
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| show | Less active compound, Inactive compound, or Another active compound.
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| What is a prodrug? | show 🗑
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| What are two examples of prodrugs? | show 🗑
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| What is the first-pass effect? | show 🗑
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| show | the volume of blood that is completely cleared of the drug per unit time
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| show | Filtration, Active secretion, and reabsorption
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| The passage of active, unchanged drug from the blood stream through the glomerulus into the urine is called? | show 🗑
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| show | Active secretion
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| The process of the drug returning to the blood stream before reaching the urine is known as what? | show 🗑
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| show | the amount of time it takes for the plasma concentration or the amount of a drug in the body (after absorption and distribution) to be reduced by 50 percent.
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| show | clearance
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| How would a decrease in clearance affect the half-life of a drug, and how will that affect the drug concentration in the blood? | show 🗑
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| show | toxicity (in some cases)
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| When does a drug reach steady state? | show 🗑
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| show | 5
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| show | once per day
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| show | twice per day or three to four times per day
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| show | the effects of the body on drugs
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| show | absorption, distribution, metabolism, and excretion
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| show | the amount - stated as a percentage - of a drug that reaches the systemic circulation after extra-vascular administration.
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| What would the bioavailability of an IV drug be? | show 🗑
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| show | reduced extent of absorption
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| show | free(unbound,not protein bound) or protein bound
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| Drugs must be in which form to be active and have a therapeutic effect? | show 🗑
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| show | albumin, in the liver
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