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Test 1 drugs- cholinergic, anticholinergic lilk8tob

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Name
Info
bethanechol (Urecholine) general class:   cholinergic  
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bethanechol (Urecholine)- direct or indirect acting:   direct acting  
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bethanechol (Urecholine)- drug effect:   increased bladder tone, increased motility  
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bethanechol (Urecholine)- uses   treatment of nonobstructive urinary retention; GI retention  
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bethanechol (Urecholine) side effects:   Not for use w/ hyperthyroidism, peptic ulcer, bronchial asthma, epilepsy  
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donepezil (Aricept)- general class:   cholinergic  
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donepezil (Aricept)- direct or indirect:   anticholinesterase (indirect acting)  
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donepezil (Aricept)- drug effect:   increases levels of ACh in brain by preventing its breakdown  
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donepezil (Aricept)- uses:   mild to moderate Alzheimer's  
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donepezil (Aricept)- SE   avoid drugs w/ anticholinergic properties  
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physostigmine (Antilirium)- general class:   cholinergic  
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hysostigmine (Antilirium)- direct or indirect:   anticholinesterase (indirect acting)  
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hysostigmine (Antilirium)- drug effect:   incrases ACh by inhibiting AChE; improves muscle strength  
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hysostigmine (Antilirium)- uses   myastenia gravis, TCA overdose  
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hysostigmine (Antilirium)- SE:   caution w/ epilepsy, bronchial asthma, bradycardia, hyperthyroidism, dysrhythmies, peptic ulcer  
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atropine- general class:   cholinergic-blocking  
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atropine- natural/synthetic:   naturally occurring anticholinergic  
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atropine- drug effect   cholinergic blocking effects on heart and smooth muscles of bronchi & intestines  
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atropine- uses   preop (reduces secretions), bradycardia  
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atropine- SE:   angle-closure glaucoma, adhesions between iris &lens, some types of asthma, ulcerative colitis  
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dicyclomine (Bentyl)- general class:   cholinergic-blocking  
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dicyclomine (Bentyl)- natural/synthetic   synthetic anticholinergic  
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dicyclomine (Bentyl)- drug effect   antispasmodic cholinergic blocker  
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dicyclomine (Bentyl)- uses   functional disturbances of GI motility *IBS*, infant colic  
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dicyclomine (Bentyl)- SE   GI obstruction, myasthenia gravis, narrow-angle glaucoma  
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scopalamine (Transderm Scop)- general class   cholinergic-blocking  
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scopalamine (Transderm Scop)- natural/synthetic   naturally occurring anticholinergic  
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scopalamine (Transderm Scop)- drug effect   corrects the imbalance between ACh and NE in the brain (especially the vomit center)  
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scopalamine (Transderm Scop)- uses   motion sickness, preop for control of secretions  
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albuterol (Ventolin)- general class   adrenergic  
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albuterol (Ventolin)- category   selective beta2 adrenergic  
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albuterol (Ventolin)- drug effect   bronchodilator  
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albuterol (Ventolin)- uses   asthma  
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epinephrine (Adrenalin)- general class   adrenergic  
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epinephrine (Adrenalin)- category   nat. occurring catecholamine, produced by adrenal medulla; mixed alpha & beta  
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epinephrine (Adrenalin)- drug effect   vasoconstriction, increased BP, cardiac stimulation, dilation of bronchioles  
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epinephrine (Adrenalin)- uses   acute asthma attack, anaphylaxis, restore cardiac rhythm in cardiac arest, nasal decongestant  
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epinephrine (Adrenalin)- SE   not for: narrow-angle glaucoma, shock from trauma, coronary insufficiency, labor  
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pseudoephedrine (Afrin)- general class   adrenergic  
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pseudoephedrine (Afrin)- category   natural plant alkaloid  
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pseudoephedrine (Afrin)- drug effect   decongestant (nasal), orally administered  
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pseudoephedrine (Afrin)- uses   congested nose  
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pseudoephedrine (Afrin)- SE   ephedra is a component of certain OTC herbal dietary supplements, so it is unsafe to use both  
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dobutamine (Dobutrex)- general class   adrenergic  
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dobutamine (Dobutrex)- category   beta1-selective vasoactive adrenergic drug  
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dobutamine (Dobutrex)- drug effect   increases cardiac output by increasing contractility (positive inotropy), whic ups SV; similar to dopamine  
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dobutamine (Dobutrex)- uses   heart failure  
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phentolamine (Regitine)- general class   adrenergic-blocking  
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phentolamine (Regitine)- alpha1/2/nonspecific   alpha blocker  
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phentolamine (Regitine)- drug effect   reduces peripheral vascular resistance  
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phentolamine (Regitine)- uses   hypertension, pheochromocytoma, extravasation of vasopressors  
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phentolamine (Regitine)- SE   those who have had an MI, coronary artery disease  
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prazosin (Minipress)- alpha1/2/nonspecific   alpha1-adrenergic blocker  
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prazosin (Minipress)- drug effect   relaxes & dilates the vasculature and smooth muscle around the prostate  
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prazosin (Minipress)- uses   hypertension, urinary obstruction in men w/ BPH  
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prazosin (Minipress)- SE   dramatically lowers BP, orthostatic hypotension  
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metaprolol (Lopressor)- general class   adrenergic-blocking  
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metaprolol (Lopressor)- alpha/beta/1/2   beta1-blocker  
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metaprolol (Lopressor)- uses   post-MI, hypertension, early MI  
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propranolol (Inderal)- general category   adrenergic-blocking  
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propranolol (Inderal)- alpha/beta   nonselective beta1 and beta2 blocker  
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propranolol (Inderal)- uses   angina, hypertension, dysrhythmias, post-MI, migraine, tremor, pheochromocytoma  
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propranolol (Inderal)- SE   bronchial asthma, bradycardia, Raynaud's disease  
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sotalol (Betapace)- general class   adrenergic-blocking  
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sotalol (Betapace)- alpha/beta   nonselective beta blocker  
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sotalol (Betapace)- uses   difficult-to-treat dysrhythmias  
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