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Hematology, RBC morphology

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Answer
Acanthocyte   irregularly spiculated, spur cells, may occur in cats with hepatic lipidosis, occasionally in dogs with liver disease.  
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NRBC   nucleated red blood cells, normal in avians and reptiles, early release of immature cells (anemia) in dogs or cats.  
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Schistocyte   fragmented RBCs, intravascular trauma, DIC, or iron deficiency.  
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Stomatocyte   central pallor is slit-like, may be artifactual, associated with anemias, liver disease.  
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Crenated RBC   shriveled RBC, spiculated, may occur with too much EDTA, slow drying of blood film.  
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Rouleaux formation   stacked coin appearance, normal in horses, may be artifactual if blood is held too long or refrigerated.  
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Heinz bodies   rounded projections, stain pale with wright's stain, <5% is normal in cats, increased with lymphosarcoma, hyperthyroidism, and diabetes mellitus in cats.  
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Howell-jolly bodies   stain as blue dots, related to splenic removal or disorder.  
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Echinocyte   regularly spiculated, artifactual, associated with slow drying of blood films or too much EDTA, may be associated with renal disease and lymphosarcoma in dogs.  
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Basophilic stippling   presence of small, dark blue dots, usually characteristic of lead poisoning in dogs  
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Agglutination   clumping formation, occurs in immune-mediated disorders  
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Created by: tarynsmethers
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