AP Art History
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Proteins that regulate cell check points | show 🗑
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show | Bak, Bax, bcl-2
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Bak | show 🗑
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show | Encourages apoptosis. Stimulated release of cytochrome c from mitochondria, activating classes, stimulating death
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show | Prevents apoptosis
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show | Increase in number of normal cells
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show | Presence of cells that are abnormal but not cancer
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show | p53
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show | Made by liver. Bonds to sex hormones to keep their levels regulated
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Insulin-like growth factor 1 | show 🗑
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mSEPT9 | show 🗑
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show | Cancer Antigen 125. Protein found in blood. Cancer cells secrete more of it
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show | In epithelial cells (skin, hollow organ lining, various tissues)
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show | Carcinomas in skin cells
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show | Form in glandular cells in epithelial tissues that secrete fluids. (Some breast cancers, prostate cancer, lung sometimes, and pancreatic sometimes)
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show | Melanocytes are cells that secrete melanin. Located in stratum basale (chemo resistant)
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show | Mesoderm turns into mesenchyme. Mesenchyme develops into connective tissue (bone, fat, cartilage, blood). Sarcomas=cancer from mesenchyme tissues. Rare but return and spread
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show | Bone sarcoma. High grade (usually in kids) divide a lot and donât resemble bone
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Soft tissue sarcoma | show 🗑
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Lymphoma | show 🗑
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show | Start in bone marrow or blood. Lymphoblastic come from immature white blood cells. Myeloid come from immature blood cells. White blood cell count increased
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show | Come from immature cells in fetus. Genetically formed
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Alkylating agents | show 🗑
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Alkylating agents drawbacks | show 🗑
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Antimetabolties | show 🗑
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show | Chemo type. Topoismerase enzymes prevent dna from supercooling. These stall replication machinery
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show | Chemo type. Block cells from doing mitosis. Bind to spindle apparatus, microtubules, and actin components
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