Comprehensive Cards
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show | lipid soluble
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Decreased response to a drug with prolonged use is... | show 🗑
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show | patient, drug, dosage, time, route, documentation
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Water solubility, reduced blood flow, ionized, small surface area, and bowel hyperactivity are... | show 🗑
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show | blood brain, blood-eye, or fetal placental
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show | decreased distribution (intrinsic activity)
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show | liver
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show | increase in amount needed
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Effect of competition for drug metabolizing enzymes on drug levels: | show 🗑
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show | therapeutic index
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This organ must be mature and healthy in order to effectively excrete drugs: | show 🗑
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show | IV, IM, SubQ
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Non-protein bound, water soluble, ionized: | show 🗑
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Safety level of drugs with a narrow therapeutic range: | show 🗑
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show | half-life
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show | agonist
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Type of drug that prevents receptor activation by endogenous regulatory molecules and have no effect of their own: | show 🗑
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Effect of food on rate of drug absorption: | show 🗑
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Effect of grapefruit on the levels of many drugs: | show 🗑
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Disease produced by drugs: | show 🗑
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show | LFT (tests AST and ALT levels)
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show | BUN, creatinine
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Test used to monitor for bone marrow suppression: | show 🗑
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show | Category X
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show | Administer just after breastfeeding, use drugs that are water-soluble with a short half-life
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show | penicillins
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show | cephalosporins
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DOC for treatment of an anaphylactic response: | show 🗑
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show | vancomycin
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show | tetracycline
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show | erythromycin
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Major toxic effects of this class of antimicrobials are ototoxicity and nephrotoxicity: | show 🗑
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show | tetracycline
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show | sulfonamides (sulfamethexazole)
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DOC for antibiotic associated colitis: | show 🗑
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This antimicrobial can produce a disulfiram-like reaction if comined with alcohol: | show 🗑
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show | Amphotericin B
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This antimicrobial is used to treat herpes simplex virus (HSV): | show 🗑
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Contraindicated for persons with hypersensitivity to eggs: | show 🗑
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show | anti-retroviral drugs
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Reduction in viral load: | show 🗑
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Levodopa, Levodopa with Carbidopa (Sinemet), Amantadine (Symmetrel), and Benztoprine (Cogentin) are... | show 🗑
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show | eight hours
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To avoid abrupt cessation of this prototype drug's effects--spread out protein intake throughout the day: | show 🗑
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show | Levodopa
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show | Alzheimer's disease
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show | anti-epileptic drugs
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DOC for treatment of status epilepticus: | show 🗑
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show | Dilantin
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This anti-seizure drug should not be administered at a rate faster than 2 mg/min: | show 🗑
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show | Morphine/Fentanyl
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show | Pentazocine/Narcan
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To avoid this adverse effect, morphine must be administered slowly over 5 minutes: | show 🗑
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show | twelve
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Constipation, respiratory depression, urinary retention, emesis, increased ICP, and sedation are adverse effects of this class of analgesics: | show 🗑
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show | acetaminophen
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show | drugs to treat migraines
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show | Cox 2 (aspirin)
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show | Salicylism
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show | aspirin
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show | acetylcholine
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Location of alpha 1 sympathetic system receptors: | show 🗑
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show | heart, kidneys
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show | lungs
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show | pupil dilation
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Response to activation of beta 1 receptors: | show 🗑
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Response to activation of beta 2 receptors: | show 🗑
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Response to blockade of alpha 1 receptors: | show 🗑
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show | decreased heart rate, no release of renin
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show | bronchoconstriction
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Response to activation of muscarinic receptors on the bladder: | show 🗑
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Response to activation of muscarinic receptors on the eye: | show 🗑
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show | bronchodilation
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show | decrease in output
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Response to blockade of muscarinic receptors on the heart: | show 🗑
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show | Prazosin
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Prototype drug used to treat hypertension, decrease 02 demand, and/or to decrease HR for rapid dysrhythmias through blockade of beta 1 receptors: | show 🗑
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show | Bethanecol
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Prototype cholinesterase inhibitor used to treat myasthenia gravis: | show 🗑
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show | atropine
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Prototype cholinergic (muscarinic) antagonist: | show 🗑
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show | pupil dilation
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Drugs which increase contractility are: | show 🗑
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show | ACE inhibitors
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show | water and sodium excretion (lowers blood pressure)
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show | vasodilation (decreased afterload)
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show | take at bedtime; rise slowly
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show | 100
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show | 60
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Potential adverse effect of all antihypertensives | show 🗑
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Rate at which furosemide (Lasix) is given IV in order to avoid hypotension: | show 🗑
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Normal (therapeutic) digoxin level: | show 🗑
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show | increases contractility
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show | decreases
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show | reflex tachycardia, decreases BP
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Periodic liver function tests are indicated for users of this cholesterol lowering agent: | show 🗑
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show | Questran (cholestyramine)
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Used for hypertensive crises. Adverse effects include hypertension, cyanide poisoning, and thiocyanate toxicity: | show 🗑
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Toxicity that is characterized by bradycardia, GI symptoms, and CNS effects like visual disturbances. Toxicity is potentiated by hypokalemia: | show 🗑
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show | ARB's (angiotensin receptor blockers)
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show | ACE inhibitors
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show | Beta blockers
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Clients taking this antihypertensive agent must be monitored for hyperkalemia: | show 🗑
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show | Lasix
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An adverse effect of this drug is a persistent dry irritating nonproductive cough due to bradykinin accumulation: | show 🗑
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Digoxin, Dopamine, Dobutamine are referred to as: | show 🗑
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DOC for iron deficiency anemia: | show 🗑
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DOC for Vitamin B12 deficiency: | show 🗑
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show | folic acid
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Erythropoietin growth factor: | show 🗑
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show | Neupogen
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show | Neumega
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DOC for prevention of arterial thromboses: | show 🗑
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Thrombolytic: | show 🗑
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DOC for prevention of venous thromboses: | show 🗑
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Antidote for heparin: | show 🗑
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Antidote for warfarin (Coumadin): | show 🗑
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show | dark green, black tarry stools
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Rationale for test dose prior to IV administration of iron: | show 🗑
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show |
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Adverse effect associated with filgastrin (Neupogen) administration: | show 🗑
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show | fluid retention, cardiac dysrhythmias
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Lab test to monitor effectiveness of ferrous sulfate: | show 🗑
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Lab test to monitor effectiveness of epoeitin alfa (Epogen): | show 🗑
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show | CBC, platelets
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show | CBC, platelets
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Lab test to monitor effectivenes of warfarin: | show 🗑
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Lab test to monitor effectiveness of heparin: | show 🗑
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show | 1.5-2x aPTT(nl 40 sec; target 60-80sec)
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Target PT range for warfarin anticoagulation: | show 🗑
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show | 3-4.5
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show | low (normal=5,000-10,000)
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show | low (normal=150,000-400,000)
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Potential adverse effect of heparin therapy: | show 🗑
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Anticoagulant of choice during pregnancy: | show 🗑
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show | 8-12 hours after admin. Peak several days
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Timeframe in which thrombolytics must be administred following symptom onset: | show 🗑
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Most serious adverse effect associated with use of thrombolytics: | show 🗑
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show | Streptokinase
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Interpretation of a peak flow meter reading in the yellow zone: | show 🗑
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Inhaled beta 2 agonist used for quick relief during an asthma attack: | show 🗑
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show | Beta 2 agonists-Albuterol
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Pseudoephedrine (Sudafed) and phenylphrine (Neosynephrine): | show 🗑
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show | oral/nasal antihistamines
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Expected action of guafenesin (Mucinex): | show 🗑
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show | reacts directly with mucus which results in increased water content of secretions
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Hypokalemia, immunosupression, fluid retention, ulcerogenic, hyperglycemia: | show 🗑
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Adverse effect of use of nasal decongestant sprays for more than 3-5 days: | show 🗑
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Adverse effect of first generation antihistamines: | show 🗑
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show | Singulair
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show | Cromolyn (Intal)
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Oropharyngeal candidiasis and dysphonia are possible adverse effects of this inhaled prototype drug: | show 🗑
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With this prototype drug use to prophylactically treat asthma the nurse must monitor for toxicity. Therapeutic range is 10-20 mcg/ml. | show 🗑
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