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1a. Pharmacology Midterm review ch 1-10

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What is the rate-limiting factor for drug distribution?   show
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What term is used to describe a drug which binds to a receptor and has an action similar to that of an endogenous chemical?   show
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What can drugs combine with in addition to receptors?   show
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By what process can one drug increase the metabolism of both itself and other drugs?   show
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show nonionized  
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What term is used to decribe the situation when the effect of two drugs given together is more intense or longer in duration than the sum of their individual actions?   show
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show ceiling effect  
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show affinity  
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What is the study of the activity of drugs within the body known as?   show
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show anaphylactic reaction  
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An all-inclusive effect on the whole body is also called a(n)______ effect.   show
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From what two organs are most drugs eliminated?   show
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show The drug loses an electron and gains an oxygen atom.  
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How does grapefruit interact with certain drugs?   show
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What is a classic example of a drug that is eliminated by a zero-order pharmacokinetic process?   show
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Why are the intestines the major site of drug absorption after oral administration of drugs?   show
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show 12 hours  
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In what way are the capillaries in the central nervous system (CNS) different from other capillaries?   show
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What does bioavailability reflect?   show
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What does the abbreviation ADME stand for?   show
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What is the most serious allergic reaction to penicillins?   show
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show killing the bacteria without harming the patient.  
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What bacterial pathway do sulfonamides interfere with?   show
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show metabolism  
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show staphylococcus resulting in toxic shock syndrome.  
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show white blood cell count above 12,000 and fever above 101 degrees Fahrenheit.  
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What is true of a bacteriostatic antibiotic?   show
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By which century were the organisms that cause cholera, syphilis, and leprosy isolated and identified?   show
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show vancomycin  
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Which statement regarding linezolis (Zyvox) is incorrect?   show
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show sulfonamides  
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What term is used to describe antibiotic treatment that is begun before the results of the organism culture have been returned?   show
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show tetracyclines  
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Which of the following drugs is classified as a macrolide?   show
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show aerobic  
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What is the most frequent form of bacterial resistance to antibiotics?   show
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show sepsis  
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show to prevent cross-contamination  
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show metronidazole  
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show improved activity against gram-negative bacteria  
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Why is it more difficult to develop antiviral drugs than it is to develop antibiotics?   show
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Which of the following choices represents a class of antiretroviral drugs?   show
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show Antifungals interfere with the synthesis of ergosterol, a building block for fungal cell membranes.  
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show herpes  
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How can antibiotics worsen fungal infections?   show
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Which of the following antifungal drugs should be taken with a fatty meal and can be used safely in children?   show
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What is a route by which most common viruses spread?   show
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What pair of viruses below are examples of latent viruses?   show
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show nails  
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show virion  
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What is becoming a common dosing method for treating fungal nail infections?   show
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Which of the following drugs is used to treat influenza A or influenza B?   show
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Which drug or drug class listed below is least likely to be used to treat side effects associated with amphotericin B?   show
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show amantadine  
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show enfuvirtide  
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show permeability  
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What term is used to describe a specific molecule produced by B-lymphocyles with help from T helper cells and other mechanisms?   show
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show viroconazole  
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How are fungal and human cells similar?   show
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show abacavir  
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Which of the following drugs is an example of a selective 5-HT receptor agonist?   show
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show cocaine  
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show morphine, codeine, oxycodone, and meperidine  
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Which of the following drugs can be used to reverse the effects of a narcotic?   show
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show morphine  
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What is not an aspect of balanced anesthesia?   show
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show epinephrine  
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What is the only neuromuscular blocker that acts via a depolarizing mechanism?   show
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show anticholinesterases  
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Which of the following general anesthetics is administered intravenously?   show
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What class of drugs may be used to treat migraine headaches?   show
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show pain perception  
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Which of the following drugs are the most used preoperative sedatives?   show
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What is the most inportant action of alpha-adrenergic receptors?   show
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show afferent and efferent  
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Which drug listed below can be administered as a nasal spray to treat a migraine attack?   show
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show pain  
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show dependence  
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show mu, kappa, delta  
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show fentanyl (Actiq)  
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show It inhibits the reuptake of serotonin into certain neurons in the brain  
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What drug used to treat alcohol addiction interferes with the metabolism of ethanol?   show
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show selegiline (Eldepryl)  
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Tardive dyskinesia is associated with the long-term use of which psychiatric medication?   show
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show dopamine and serotonin  
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Which or the following new antipsychotic drugs is classified today as being "atypical"?   show
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Which of the following is a symptom of alcohol withdrawal?   show
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show amitriptyline  
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show MAOIs  
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show benztropine (Cogentin)  
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show bipolar mood disorder  
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Which drug used to treat depression is also used for smoking cessation?   show
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Which of the following antianziety drugs is not a benzodiazepine?   show
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Which of the following drugs used to treat insomnia is not a DEA scheduled controlled substance?   show
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What class of drugs is part of the standard of care for alcohol (ethanol) detoxification?   show
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show gastrointestinal-nausea, vomiting, and anorexia; neuromuscular-tremors; weight- weight gain; renal- increased thirst and urination  
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show imipramine  
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During which stages of sleep does dreaming occur?   show
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What term is used to describe anxiety for which there is no identifiable source than from within the patient?   show
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show divalproex (Depakote)  
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show gingko  
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What dopamine precursor is used to treat Parkinson patients?   show
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Which pair of anticonvulsants is most likely to interact with other drugs a patient may be taking?   show
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Which anticonvulsant does not appear to act via GABA receptors and is frequently used to treat neuropathic pain?   show
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show Lewy Bodies  
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What are the most common side effects of antiseizure medications?   show
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Which of the following anticonvulsants is also used to treat manic episodes in bipolar mood disorders?   show
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show acetylcholinesterase inhibitors  
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Which of the following anticonvulsants is correctly paired with the process it most likely affects?   show
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What combination drug contains levodopa plus an inhibitor of peripheral levodopa metabolism?   show
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What is the potential way in which antiepileptic medications can interact with each other and other drugs?   show
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show status epiepticus  
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The prevalence of Parkinson's disease is highest in what age group?   show
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Which drug used to treat ADD/ADHD is not a controlled substance?   show
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show interferon beta-1a (Avonex, Rebif), interferon beta-1b (Betaseron), mitoxantrone (Novantrone), and baclofen  
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show ethosuximide (Zarontin)  
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show absence seizure  
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Which neurotranmitter is deficient in the nigrostriatal pathways of patients with Parkinson's disease?   show
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show diazepam (Valium)  
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What two neurotransmitters in the brain appear to play the greatest role in seizures?   show
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Which of the following medication is least likely to be used to treat or stop an acute asthma attack?   show
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Which of the following antitussives is a DEA controlled substance?   show
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show anxiety, difficulty in concentrating, gastrointestinal diturbances, and increased appetite and weight gain  
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show 35-55%  
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Which of the following is a reversible syndrome in which breathing may be difficult?   show
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show status asthmaticus  
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Which repiratory medication listed below is an inhaled coricosteroid?   show
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With which device, used to administer asthma or COPD medication, does a stream of air flow past a liquid to create a fine mist for the patient to inhale?   show
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An asthma attack consists of how many phases or responses?   show
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What is the least sedating OTC antihistamine and the only one approved by the FDA for cold symptoms?   show
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Dornase alfa (Pulmozyme) may be used to treat what two lung diseases?   show
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What are two signs or symptoms of nicotine excess?   show
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Which of the following forms of nicotine replacement therapy is only available by prescription?   show
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show tiotropim (Spiriva)  
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show isoniazid (Laniazid, Nydrzid), rifampin (Rifadin. Rimactine), ciproflozacin (Cipro), and rifapentine (Priftin)  
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show ipratropium (Atrovent)  
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What is the most useful measure for assessing the severity of asthma on a regular basis?   show
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show guaifesesin (Mucinex)  
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show anticholinergic responses, hyperactivity in some children, and sedation  
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show beta blockers  
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show lactulose (Enulose)  
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show nitazoxanide (Alinia)  
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Which of the drugs listed below is a monoclonal antibody that binds to tumor necrosis factor (TNF) and is indicated for the treatment of Crohn's disease?   show
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show bismuth subsalicylate-metronidazole-tetracycline (Helidac)  
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show sucralfate (Carafate)  
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Which drug listed below is an example of a phase II drug used to treat GERD?   show
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Which drug below acts on 5-HT-4 receptors and is used to treat constipation-predominant irritable bowel syndrome?   show
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Which drug listed below acts to facilitate the admixture of fat and water to soften stool?   show
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What is a potential problem associated with low-fiber diets?   show
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show cimetidine (Tagamet)  
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If abdominal pain is caused by the release of an allergy or inflammation mediator, what mast cell stabilizer may be prescribed?   show
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What is another term for heartburn?   show
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show fermentability, water-holding capacity, stool-bulking capacity, and solubility  
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For the treatment of hepatitis, which drug listed below is an interferon linked with a branched polyethylene glycol (PEG) molecule in order to allow once weekly dosing?   show
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show diphonoxylate-atropine (Lomotil)--C-V  
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show dopamine  
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What is the drug of choice in treating malabsorption syndrome due to panceratic insufficiency?   show
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show ondansetron (Zofran)  
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What is praziquantel (Biltricide) used to treat?   show
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What GI disorder is characterized by inflammation of the large bowel with the patient experiencing diarrhea containing blood, mucus, and pus?   show
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Created by: danz
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