1a. Pharmacology Midterm review ch 1-10
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What is the rate-limiting factor for drug distribution? | show 🗑
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What term is used to describe a drug which binds to a receptor and has an action similar to that of an endogenous chemical? | show 🗑
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What can drugs combine with in addition to receptors? | show 🗑
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By what process can one drug increase the metabolism of both itself and other drugs? | show 🗑
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show | nonionized
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What term is used to decribe the situation when the effect of two drugs given together is more intense or longer in duration than the sum of their individual actions? | show 🗑
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show | ceiling effect
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show | affinity
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What is the study of the activity of drugs within the body known as? | show 🗑
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show | anaphylactic reaction
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An all-inclusive effect on the whole body is also called a(n)______ effect. | show 🗑
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From what two organs are most drugs eliminated? | show 🗑
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show | The drug loses an electron and gains an oxygen atom.
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How does grapefruit interact with certain drugs? | show 🗑
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What is a classic example of a drug that is eliminated by a zero-order pharmacokinetic process? | show 🗑
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Why are the intestines the major site of drug absorption after oral administration of drugs? | show 🗑
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show | 12 hours
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In what way are the capillaries in the central nervous system (CNS) different from other capillaries? | show 🗑
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What does bioavailability reflect? | show 🗑
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What does the abbreviation ADME stand for? | show 🗑
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What is the most serious allergic reaction to penicillins? | show 🗑
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show | killing the bacteria without harming the patient.
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What bacterial pathway do sulfonamides interfere with? | show 🗑
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show | metabolism
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show | staphylococcus resulting in toxic shock syndrome.
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show | white blood cell count above 12,000 and fever above 101 degrees Fahrenheit.
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What is true of a bacteriostatic antibiotic? | show 🗑
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By which century were the organisms that cause cholera, syphilis, and leprosy isolated and identified? | show 🗑
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show | vancomycin
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Which statement regarding linezolis (Zyvox) is incorrect? | show 🗑
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show | sulfonamides
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What term is used to describe antibiotic treatment that is begun before the results of the organism culture have been returned? | show 🗑
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show | tetracyclines
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Which of the following drugs is classified as a macrolide? | show 🗑
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show | aerobic
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What is the most frequent form of bacterial resistance to antibiotics? | show 🗑
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show | sepsis
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show | to prevent cross-contamination
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show | metronidazole
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show | improved activity against gram-negative bacteria
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Why is it more difficult to develop antiviral drugs than it is to develop antibiotics? | show 🗑
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Which of the following choices represents a class of antiretroviral drugs? | show 🗑
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show | Antifungals interfere with the synthesis of ergosterol, a building block for fungal cell membranes.
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show | herpes
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How can antibiotics worsen fungal infections? | show 🗑
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Which of the following antifungal drugs should be taken with a fatty meal and can be used safely in children? | show 🗑
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What is a route by which most common viruses spread? | show 🗑
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What pair of viruses below are examples of latent viruses? | show 🗑
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show | nails
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show | virion
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What is becoming a common dosing method for treating fungal nail infections? | show 🗑
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Which of the following drugs is used to treat influenza A or influenza B? | show 🗑
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Which drug or drug class listed below is least likely to be used to treat side effects associated with amphotericin B? | show 🗑
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show | amantadine
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show | enfuvirtide
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show | permeability
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What term is used to describe a specific molecule produced by B-lymphocyles with help from T helper cells and other mechanisms? | show 🗑
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show | viroconazole
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How are fungal and human cells similar? | show 🗑
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show | abacavir
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Which of the following drugs is an example of a selective 5-HT receptor agonist? | show 🗑
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show | cocaine
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show | morphine, codeine, oxycodone, and meperidine
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Which of the following drugs can be used to reverse the effects of a narcotic? | show 🗑
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show | morphine
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What is not an aspect of balanced anesthesia? | show 🗑
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show | epinephrine
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What is the only neuromuscular blocker that acts via a depolarizing mechanism? | show 🗑
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show | anticholinesterases
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Which of the following general anesthetics is administered intravenously? | show 🗑
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What class of drugs may be used to treat migraine headaches? | show 🗑
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show | pain perception
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Which of the following drugs are the most used preoperative sedatives? | show 🗑
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What is the most inportant action of alpha-adrenergic receptors? | show 🗑
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show | afferent and efferent
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Which drug listed below can be administered as a nasal spray to treat a migraine attack? | show 🗑
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show | pain
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show | dependence
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show | mu, kappa, delta
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show | fentanyl (Actiq)
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show | It inhibits the reuptake of serotonin into certain neurons in the brain
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What drug used to treat alcohol addiction interferes with the metabolism of ethanol? | show 🗑
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show | selegiline (Eldepryl)
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Tardive dyskinesia is associated with the long-term use of which psychiatric medication? | show 🗑
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show | dopamine and serotonin
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Which or the following new antipsychotic drugs is classified today as being "atypical"? | show 🗑
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Which of the following is a symptom of alcohol withdrawal? | show 🗑
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show | amitriptyline
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show | MAOIs
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show | benztropine (Cogentin)
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show | bipolar mood disorder
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Which drug used to treat depression is also used for smoking cessation? | show 🗑
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Which of the following antianziety drugs is not a benzodiazepine? | show 🗑
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Which of the following drugs used to treat insomnia is not a DEA scheduled controlled substance? | show 🗑
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What class of drugs is part of the standard of care for alcohol (ethanol) detoxification? | show 🗑
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show | gastrointestinal-nausea, vomiting, and anorexia; neuromuscular-tremors; weight- weight gain; renal- increased thirst and urination
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show | imipramine
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During which stages of sleep does dreaming occur? | show 🗑
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What term is used to describe anxiety for which there is no identifiable source than from within the patient? | show 🗑
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show | divalproex (Depakote)
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show | gingko
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What dopamine precursor is used to treat Parkinson patients? | show 🗑
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Which pair of anticonvulsants is most likely to interact with other drugs a patient may be taking? | show 🗑
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Which anticonvulsant does not appear to act via GABA receptors and is frequently used to treat neuropathic pain? | show 🗑
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show | Lewy Bodies
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What are the most common side effects of antiseizure medications? | show 🗑
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Which of the following anticonvulsants is also used to treat manic episodes in bipolar mood disorders? | show 🗑
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show | acetylcholinesterase inhibitors
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Which of the following anticonvulsants is correctly paired with the process it most likely affects? | show 🗑
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What combination drug contains levodopa plus an inhibitor of peripheral levodopa metabolism? | show 🗑
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What is the potential way in which antiepileptic medications can interact with each other and other drugs? | show 🗑
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show | status epiepticus
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The prevalence of Parkinson's disease is highest in what age group? | show 🗑
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Which drug used to treat ADD/ADHD is not a controlled substance? | show 🗑
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show | interferon beta-1a (Avonex, Rebif), interferon beta-1b (Betaseron), mitoxantrone (Novantrone), and baclofen
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show | ethosuximide (Zarontin)
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show | absence seizure
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Which neurotranmitter is deficient in the nigrostriatal pathways of patients with Parkinson's disease? | show 🗑
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show | diazepam (Valium)
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What two neurotransmitters in the brain appear to play the greatest role in seizures? | show 🗑
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Which of the following medication is least likely to be used to treat or stop an acute asthma attack? | show 🗑
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Which of the following antitussives is a DEA controlled substance? | show 🗑
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show | anxiety, difficulty in concentrating, gastrointestinal diturbances, and increased appetite and weight gain
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show | 35-55%
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Which of the following is a reversible syndrome in which breathing may be difficult? | show 🗑
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show | status asthmaticus
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Which repiratory medication listed below is an inhaled coricosteroid? | show 🗑
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With which device, used to administer asthma or COPD medication, does a stream of air flow past a liquid to create a fine mist for the patient to inhale? | show 🗑
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An asthma attack consists of how many phases or responses? | show 🗑
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What is the least sedating OTC antihistamine and the only one approved by the FDA for cold symptoms? | show 🗑
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Dornase alfa (Pulmozyme) may be used to treat what two lung diseases? | show 🗑
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What are two signs or symptoms of nicotine excess? | show 🗑
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Which of the following forms of nicotine replacement therapy is only available by prescription? | show 🗑
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show | tiotropim (Spiriva)
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show | isoniazid (Laniazid, Nydrzid), rifampin (Rifadin. Rimactine), ciproflozacin (Cipro), and rifapentine (Priftin)
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show | ipratropium (Atrovent)
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What is the most useful measure for assessing the severity of asthma on a regular basis? | show 🗑
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show | guaifesesin (Mucinex)
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show | anticholinergic responses, hyperactivity in some children, and sedation
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show | beta blockers
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show | lactulose (Enulose)
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show | nitazoxanide (Alinia)
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Which of the drugs listed below is a monoclonal antibody that binds to tumor necrosis factor (TNF) and is indicated for the treatment of Crohn's disease? | show 🗑
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show | bismuth subsalicylate-metronidazole-tetracycline (Helidac)
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show | sucralfate (Carafate)
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Which drug listed below is an example of a phase II drug used to treat GERD? | show 🗑
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Which drug below acts on 5-HT-4 receptors and is used to treat constipation-predominant irritable bowel syndrome? | show 🗑
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Which drug listed below acts to facilitate the admixture of fat and water to soften stool? | show 🗑
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What is a potential problem associated with low-fiber diets? | show 🗑
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show | cimetidine (Tagamet)
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If abdominal pain is caused by the release of an allergy or inflammation mediator, what mast cell stabilizer may be prescribed? | show 🗑
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What is another term for heartburn? | show 🗑
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show | fermentability, water-holding capacity, stool-bulking capacity, and solubility
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For the treatment of hepatitis, which drug listed below is an interferon linked with a branched polyethylene glycol (PEG) molecule in order to allow once weekly dosing? | show 🗑
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show | diphonoxylate-atropine (Lomotil)--C-V
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show | dopamine
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What is the drug of choice in treating malabsorption syndrome due to panceratic insufficiency? | show 🗑
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show | ondansetron (Zofran)
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What is praziquantel (Biltricide) used to treat? | show 🗑
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What GI disorder is characterized by inflammation of the large bowel with the patient experiencing diarrhea containing blood, mucus, and pus? | show 🗑
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