Antacids, Antidiarrheals, Laxatives, Anti-emetics and Antinausea Agents
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Catergories of antacids? (5) | show 🗑
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Mechanism of Action for cholinergice blocking agents? | show 🗑
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MOA for aluminum, Calcium & Magnesium based antacids? | show 🗑
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MOA fo H2 antagonists? | show 🗑
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show | blocks all gastric acid secretion
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MOA for cytoprotective agents? | show 🗑
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show | Choliniergic blocking agent (anticholinergic) works as an antacid and antispasmotic
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Therapeutic uses of ALuminum, Magnesium, & Calcium based antacids? (3) | show 🗑
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show | diarrhea; excessive use can cause systemic alkalosis;
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show | constipation; excessive use can cause systemic alkalosis;
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What is the preferred antacid in pts. with impaired renal function? | show 🗑
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show | H2 antagonist blocks H2 receptors of the acid-producing parietal cells; reduces amount of acid;
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Adverse rxn of Cimetidine (tagamet), Pepcid, Axid, & Zantac? | show 🗑
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Drug interactions of Cimetidine (tagamet), Pepcid, Axid, & Zantac? | show 🗑
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show | Pts. with impaired renal or hepatic function;
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show | proton pump inhibitor; blocks all gastric acid secretion;
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show | due to some carcinogenic concerns, only approved for the Tx of gastric/esophageal reflux disease (GERD), Zollinger-Ellison Disease;
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Drug interactions of Omeprazole (Prilosec)? | show 🗑
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Classification and MOA for Sacralfate (Carafate)? | show 🗑
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Therapeutic use of Sacralfate (Carafate)? | show 🗑
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show | constipation, Nausea;
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Pt teaching for Anactids? (3) | show 🗑
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what are the four classess of antidiarrheals? | show 🗑
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show | coat the wall of the intestines; bind with the causative bacteria or toxin and eliminate it in the stools;
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show | decrease peristalsis
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show | obtained from bacteria; restore the body's normal flora;
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MOA for Opiates? | show 🗑
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Classification of Kaopectate (PeptoBismol)? | show 🗑
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Adverse rxn of Kaopectate (PeptoBismol)? | show 🗑
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show | anticholinergic; antidiarrheal
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Adverse rxn of Belladonna Alkaloid (Donnatal)? | show 🗑
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Classification of Lactobaccilus Acidophillus? | show 🗑
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show | drowsiness, sedation, respiratory depression, bradycardia, hypotension, urinary retention;
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Classification and therapeutic use of Diphenoxylate (Lomotil) & Loperamide (Immodium)? | show 🗑
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show | drowsiness, sedation;
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show | 1. Metabolic & endocrine disorders; 2. neurologic disorders; 3. adverse side effects; 4. life style;
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show | 1. bulk forming; 2. emollient (stool softeners); 3. hyperosmotic; 4. saline;
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MOA for bulk forming laxatives? | show 🗑
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show | lower the surface tension of GI fluids allowing more water and fat to be absorbed into the stools;
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MOA for hyperosmotic laxatives? | show 🗑
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MOA for Saline laxatives? | show 🗑
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show | bulk forming laxatives
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Adverse rxn of Methyllcellulose (Citrucel) & Psyllium (Metamucil)? | show 🗑
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Classification of Mineral Oil & Docusate Salts (Surfax, Diocto-K) ? | show 🗑
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show | skin rashes, decreased absorption of vitamins, lipid pnuemonia;
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show | hyperosmotic laxative
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Therapeutic use of GoLytely? | show 🗑
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show | lowers blood ammonia levels in pts with severe hepatic involovement
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Adverse rxn of GoLytely & Lactulose (Chronulac)? | show 🗑
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Classification of Magnesium Salts (Milk Of Magnesia, Fleets Enema)? | show 🗑
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show | magnesium toxicity in pts with renal insufficiency;
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Classification of Phenolphthalein & Senna (Ex Lax & Senokot)? | show 🗑
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Adverse rxn of Phenolphthalein & Senna (Ex Lax & Senokot)? | show 🗑
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show | 1. swallow all laxative tablets with at least 6oz of water; 2. do not crush or chew enteric coated tablets; 3. long term use of laxatives may result in laxative dependence;
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show | cont. 4. notify MD immediately if you develope abdominal pain, muscle weakness, cramps, dizziness; 5. Do not take laxative if you are experiencing nausea, vomiting or abdominal pain;
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show | Dietary (fiber supplementation), Behavioral (increasing physical activity), Pharmeceutical
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How does pharmaceutical use of laxatives promote bowel movements? (3) | show 🗑
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show | 1. anticholinergics; 2. antihistamines; 3. neuroleptic Agents; 4. prokinetic agents; 5. serotonin blockers; 6. tetrahydrocannabinoid (THC);
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Indications for anti-emetics? (anticholinergics) | show 🗑
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Indications for anti-emetics? (antihistamines) | show 🗑
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Indications for anti-emetics? (Neuroleptic Agents) | show 🗑
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Indications for anti-emetics? (prokinetic agents) | show 🗑
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show | N&V associated with cancer chemotherapy;
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Indications for anti-emetics? (tertrahydrocannabinoid THC) | show 🗑
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Classification and therapeutic use of Meclizine (Antivert)? | show 🗑
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Adverse rxn of Meclizine (Antivert)? | show 🗑
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Major drug interactions of Meclizine (Antivert)? | show 🗑
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Classification and therapeutic use of Scopolomine (Trans Derm Scop)? | show 🗑
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show | drowsiness, dizziness, dry mouth, blurred vision, difficulty urinating;
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show | additive effects wih antihistamines & antidepressants;
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show | neuroletic anti-emetic used for pyschotic disorders, intractable hiccoughs, N&V;
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Adverse rxn of Prochlorperazine (Compazine)? | show 🗑
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show | blocks levodopa; additive effects with quinidine;
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Classification and MOA of Metoclopramide (Reglan)? | show 🗑
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Therapeutic use of Metoclopramide (Reglan)? | show 🗑
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Adverse rxn of Metoclopramide (Reglan)? | show 🗑
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Major drug interactions of Metoclopramide (Reglan)? | show 🗑
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show | tetrahydrocannabinoid (THC) that has an inhibitory effect on reticular formation, thalamus & cerebral cortex;
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show | N&V associated with cancer chemotherapy, appetite stimulant;
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show | drowsiness, dizziness, confusion, dry mouth, visual disturbances;
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Calssification and therapeutic use of Gansitron (Kytril) & Ondanestron (Zofran)? | show 🗑
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show | Headache, Diarrhea, bronchospasm;
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show | 1. take exactly as directed; 2. may cause drowsiness, use caution; 3. do not take with alcohol or other CNS depressants; 4. pts on Dronabinol (Marinol) should change positions slowly;
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