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Drug-to-disease Interactions

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Term
Definition
Acyclovir (Zovirax)   Affected by kidney disease  
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Allopurinol (zyloprim)   Affected by kidney disease  
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Aminoglycoside antibacterials (Amikin,gentamicin, tobramycin   Affected by kidney disease  
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Bivalirudin(Angiomax)   Affected by Kidney disease  
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Ciprofloxacin (Cipro)   Affected by kidney disease  
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Digoxin(Lanoxin)   Effected by kidney disease  
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Dofetilide (Tikosyn)   Affected by kidney disease  
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Enoxaparin (Lovenox)   Affected by kidney disease  
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Eptifibatide (Integrilin)   Affected by kidney disease  
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Flecainide (Tambocor)   Affected by kidney disease  
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Fondaparinux (Arixtra)   Affected by kidney disease  
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HCTZ   Affected by kidney disease  
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Lithium (Lithobid)   Affected by kidney disease  
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Metformin (Glucophage)   Affected by kidney disease  
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Methotrexate (Trexall)   Affected by kidney disease  
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Probenecid   Affected by kidney disease  
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Sotalol (Betapace)   Affected by kidney disease  
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Tirofiban (Aggrastat)   Affected by kidney disease  
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Tramodol (Ultram)   Affected by kidney disease  
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Vancomycin (Vancocin)   Affected by kidney disease  
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Cholesterol lowering medications such as Lipitor, Zocor, and Pravachol   Affected by liver disease  
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Lidocaine (Xylocaine)   Affected by liver disease  
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Metformin (Glucophage)   Affected by liver disease  
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Nefazodone (Serzone)   Affected by liver disease  
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Nelfinavir (Viracept)   Affected by liver disease  
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Omeprazole (Prilosec)   Affected by liver disease  
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Ondansetron (Zofran)   Affected by liver disease  
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Paclitaxel (Taxol)   Affected by liver disease  
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Propranolol (Inderal)   Affected by liver disease  
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Ritonavir (Norvir)   Affected by liver disease  
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Tamoxifen (Nolvadex)   Affected by liver disease  
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Testosterone (AndroGel)   Affeceted by liver disease  
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Triazolam (Halcion)   Affected by liver disease  
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Trazodone   Affected by liver disease  
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Warfarin (Coumadin)   Affected by liver disease  
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Antiarrhythmics (e.g. sotalol-Betapace)   Affected by heart failure (increased risk of death)  
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Nondihydropyridinecalcium channel blockers (Diltiazem and Verapamil)   Affected by heart failure (decreased cardiac conduction)  
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metformin (Glucophage)   Increased risk of lactic acidosis  
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Thiazolidinedions, such as pioglitazone (Actos) and rosiglitazone (Avandia)   Increased sodium and water retention contributing to fluid overload and edema  
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Oral corticosteroids such as prednisone (Sterapred)   Increased sodium and water retention, contributing to fluid overload and edema  
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Estrogens and Androgens   Can precipitate acute fluid retention  
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NSAIDs such as ibuprofen (Advil, Motrin)   Potentiates peripheral edema and fluid retention  
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COX-2 Inhibitors such as celecoxib (Celebrex)   Potentiates peripheral edema and fluid retention  
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Anthracycline derivatives, such as doxorubicin (Adriamycin) and daunorubicin (Cerubidine)   Increased risk of cardiomyopathies  
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Cilostazol (Pletal)   Inhibit phosphodiesterase III resulting in decreased survival rates  
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