Uni of Notts, Genes, Molecules, and Cells, first year
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| Pleiotropy | show 🗑
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| Cases where Mendelian genetics don’t determine frequency of a characteristic | show 🗑
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| Alleles | show 🗑
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| show | When a single functional (wild-type) allele of a heterozygous gene in a diploid organism provides enough protein to fulfil its purpose in the body
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| Haploinsufficiency | show 🗑
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| show | Specific alleles carried by individuals in a population which, when expressed, provides their phenotypic traits
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| show | Wild type allele is usually dominant to non-functional allele since in many cases reactions can still take place with reduced concentration of proteins, usually enzymes since they're catalysts - haplosufficiency
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| How non-functional alleles can become dominant: Haploinsufficiency | show 🗑
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| How non-functional alleles can become dominant: Quaternary structure | show 🗑
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| Polygenic | show 🗑
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| Genetic interaction example - Why the expression of 2 genes can lead to so many skin colours of peppers | show 🗑
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| Epistasis | show 🗑
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| show | When the expression of a gene is controlled by the expression of another gene, opposite of an epistatic relationship
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| show | They're determined by enzymes catalysing intermediates, each enzyme depends on previous enzymes in the pathway to create an appropriate substrate meaning their genes are hypostatic to the previous enzyme's genes
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| Penetrance | show 🗑
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| Expressivity | show 🗑
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| A cause behind variable penetrance & expressivity | show 🗑
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| show | Diagrams showing simplified relative distance between genes or markers on a chromosome as well as the type of inheritance & linkage
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| show | The distance between genes is based on the frequency of recombination during inheritance which increases the further genes are from one another, measured in centimorgans (1cM = 1% probability)
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| Physical genome map | show 🗑
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Beech47
Popular Genetics sets