anti-microbial, antifungal, antibiotic
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beta-lactam antibacterials | show 🗑
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beta-lactam drugs ineffective against bacteria that produce the enzyme..... | show 🗑
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Penicillins include these four classes: | show 🗑
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Penicillin use against: | show 🗑
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show | PO,IV,IM
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Contraindication to penicillin | show 🗑
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most common sensitivity with penicillin | show 🗑
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show | what is cephalosporins
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show | Coumadin and oral contraceptives
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Penicillin has synergistic effect with | show 🗑
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show | are bactericidal
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show | cefazolin and cephalexin, most gram-positive cocci and some gram negative bacilli
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second generation cephalosporins | show 🗑
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show | ceftazidime, broader gram negative and anaerobic coverage. Pre-op prophylaxis
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show | cefepime, broader gram positive coverage and mroe resistant to beta-lactamases
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cephalosporins excreted by | show 🗑
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show | Ancef
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cephalosporin adverse effects | show 🗑
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show | anti-coagulants, NSAIDS, alcohol
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Monobactam | show 🗑
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Monobactam | show 🗑
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show | IV or IM
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show | urine, by kidneys
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monobactam side effects | show 🗑
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show | Carbapenems, examples: Imepenem, MerpenemUses: infections, endocarditis, UTI, septicemia
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show | GI distress, allergic reactions, seizures, pseudomembranous colitis
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bacteriostatic or bactericidal | show 🗑
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show | Erythromycin (E-Mycin), clarithromycin (Biaxin), azithromycin (Zithromax)
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show | most gram positive organisms, some gram negative, some anaerobic gram negative
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show | Kidneys
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show | PO and IV
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Adverse Side effects | show 🗑
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Drug reactions with Macrolides | show 🗑
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Aminoglycosides | show 🗑
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Adverse effects of Aminoglycosides | show 🗑
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Examples of Aminoglycosides | show 🗑
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show | Peaks, Troughs, and renal functions
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Drug Interactions with Aminoglycosides | show 🗑
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show | 30-60 min after IV dose finished
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Meassure trough at this time | show 🗑
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Tetracyclines | show 🗑
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show | Tatracycline, doxycycline, minocycline
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show | in urine and feces
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Adverse reactions of tetracycline | show 🗑
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show | tetracycline
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should not use on whom | show 🗑
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show | do not give with dairy products, antacids, with oral contraceptives, or penecillins
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best to take tetracycline when? | show 🗑
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Flouroquinolones interfere with... | show 🗑
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show | broad spectrum depending on drug
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Ciprofloxacin (Cipro) | show 🗑
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show | when taking with renal or CNS disorders, seizures or those taking theophylline
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Adverse rxn of flouroquinolones or cipro | show 🗑
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Flouroquinolones given for this bioterrorism agent | show 🗑
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show | in the liver and excreted in the kidneys
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show | antacids, caffeine, phenytoin, theophylline, coumadin
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show | Legionnaire's
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Sulfonamides inhibit | show 🗑
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show | Sulfadiazole, Sulfamethoxazole, Sulfosoxazole
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Sulfanamides highly concentrate where? | show 🗑
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effective in treating UTIs, some resp and otitis media | show 🗑
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show | aerobic gram positive organisms
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Sulfonamides available routes | show 🗑
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Drug interactions... | show 🗑
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show | Drink at least 3 Liters a day as tolerated
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show | hypersenitivity rxns, delayed skin rxns, Stevens johnson syndrome of general malaise and trunk and body rash, acute hemolytic anemia and aplastic anemia, no no for pts with renal or liver dysfunction
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show | inhibits bacterial protein synthesis; used on gram-postive organisms, anaerobic organisms, PO<IV<IMmetabolized in the LIVER and excreted inBILE and URINE
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Clindamycin effects | show 🗑
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show | RNA and cell wall synthesis
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Drug of choice for MRSA | show 🗑
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show | Vancomycin
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show | Peak and trough levels
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Adverse effects | show 🗑
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VRE | show 🗑
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Metronidazole | show 🗑
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Flagyl | show 🗑
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show | anaerobic organisms, C-diff, trichomonisis, intestinal amebiasis, H.Pylori
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show | HA, dry mouth, fatigue, bitter mettalic taste, GI distress, tingling in extremities, dark urine
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DOn'ts with Flagyl | show 🗑
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show | mild to life threatening, inhaled, ingested, or implanted, more seen in immunosuppressed
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show | candida albicans
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show | AmphotericinB (Broad spectrum, IV, can produce hypokalemia, hypomagnesia, nephrotoxicity)Diflucan (Azole antifungal, impairs cell membrane, IV and PO, Candida species, hepatotoxicity) do not use with cyclosporine, coumadin, oral hypoglycemic, phenytoin
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Nystatin | show 🗑
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Antiviral agents | show 🗑
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Herpes drugs | show 🗑
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Hep B and C drugs | show 🗑
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Influenze drugs | show 🗑
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