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anti-microbial, antifungal, antibiotic

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Question
Answer
beta-lactam antibacterials   show
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beta-lactam drugs ineffective against bacteria that produce the enzyme.....   show
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Penicillins include these four classes:   show
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Penicillin use against:   show
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show PO,IV,IM  
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Contraindication to penicillin   show
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most common sensitivity with penicillin   show
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show what is cephalosporins  
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show Coumadin and oral contraceptives  
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Penicillin has synergistic effect with   show
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show are bactericidal  
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show cefazolin and cephalexin, most gram-positive cocci and some gram negative bacilli  
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second generation cephalosporins   show
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show ceftazidime, broader gram negative and anaerobic coverage. Pre-op prophylaxis  
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show cefepime, broader gram positive coverage and mroe resistant to beta-lactamases  
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cephalosporins excreted by   show
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show Ancef  
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cephalosporin adverse effects   show
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show anti-coagulants, NSAIDS, alcohol  
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Monobactam   show
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Monobactam   show
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show IV or IM  
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show urine, by kidneys  
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monobactam side effects   show
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show Carbapenems, examples: Imepenem, MerpenemUses: infections, endocarditis, UTI, septicemia  
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show GI distress, allergic reactions, seizures, pseudomembranous colitis  
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bacteriostatic or bactericidal   show
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show Erythromycin (E-Mycin), clarithromycin (Biaxin), azithromycin (Zithromax)  
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show most gram positive organisms, some gram negative, some anaerobic gram negative  
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show Kidneys  
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show PO and IV  
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Adverse Side effects   show
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Drug reactions with Macrolides   show
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Aminoglycosides   show
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Adverse effects of Aminoglycosides   show
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Examples of Aminoglycosides   show
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show Peaks, Troughs, and renal functions  
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Drug Interactions with Aminoglycosides   show
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show 30-60 min after IV dose finished  
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Meassure trough at this time   show
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Tetracyclines   show
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show Tatracycline, doxycycline, minocycline  
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show in urine and feces  
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Adverse reactions of tetracycline   show
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show tetracycline  
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should not use on whom   show
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show do not give with dairy products, antacids, with oral contraceptives, or penecillins  
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best to take tetracycline when?   show
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Flouroquinolones interfere with...   show
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show broad spectrum depending on drug  
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Ciprofloxacin (Cipro)   show
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show when taking with renal or CNS disorders, seizures or those taking theophylline  
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Adverse rxn of flouroquinolones or cipro   show
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Flouroquinolones given for this bioterrorism agent   show
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show in the liver and excreted in the kidneys  
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show antacids, caffeine, phenytoin, theophylline, coumadin  
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show Legionnaire's  
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Sulfonamides inhibit   show
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show Sulfadiazole, Sulfamethoxazole, Sulfosoxazole  
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Sulfanamides highly concentrate where?   show
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effective in treating UTIs, some resp and otitis media   show
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show aerobic gram positive organisms  
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Sulfonamides available routes   show
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Drug interactions...   show
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show Drink at least 3 Liters a day as tolerated  
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show hypersenitivity rxns, delayed skin rxns, Stevens johnson syndrome of general malaise and trunk and body rash, acute hemolytic anemia and aplastic anemia, no no for pts with renal or liver dysfunction  
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show inhibits bacterial protein synthesis; used on gram-postive organisms, anaerobic organisms, PO<IV<IMmetabolized in the LIVER and excreted inBILE and URINE  
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Clindamycin effects   show
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show RNA and cell wall synthesis  
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Drug of choice for MRSA   show
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show Vancomycin  
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show Peak and trough levels  
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Adverse effects   show
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VRE   show
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Metronidazole   show
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Flagyl   show
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show anaerobic organisms, C-diff, trichomonisis, intestinal amebiasis, H.Pylori  
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show HA, dry mouth, fatigue, bitter mettalic taste, GI distress, tingling in extremities, dark urine  
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DOn'ts with Flagyl   show
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show mild to life threatening, inhaled, ingested, or implanted, more seen in immunosuppressed  
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show candida albicans  
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show AmphotericinB (Broad spectrum, IV, can produce hypokalemia, hypomagnesia, nephrotoxicity)Diflucan (Azole antifungal, impairs cell membrane, IV and PO, Candida species, hepatotoxicity) do not use with cyclosporine, coumadin, oral hypoglycemic, phenytoin  
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Nystatin   show
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Antiviral agents   show
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Herpes drugs   show
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Hep B and C drugs   show
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Influenze drugs   show
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