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chemistryl

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Question
Answer
Nitrogenous waste that is excreted by the kidney via   show
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show 40-60percent, depending on flow rate.  
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show important for renal medullary concentration gradient (Na too).  
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BUN primarily used as   show
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Azotemia   show
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show reduced renal perfusion.  
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Renal   show
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Post-renal   show
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show urine SG.  
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Adequate min SG that is consistently   show
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show > 1030.  
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Cat SG   show
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Others SG   show
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Increased BUN and adequate SG   show
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Increased BUN and inadequate SG (isosthenuric1008-1012, concentration of plasma   show
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Low sensitivity and specificity   show
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show elevate.  
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show BUN.  
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show dietary protein.  
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show ammonia by bacteria in the gut.  
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Ammonia diffuses across the gut into   show
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show urea.  
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Minor elevations of BUN   show
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Liver disease   show
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show Ammonia absorbed by the gut is not carried to the liver.  
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show Increased glomerular filtration rate.  
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Creatinine   show
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Excreted almost exclusively by glomerular filtration   show
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show creatinine.  
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show creatinine.  
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Less influenced by non-renal factors then BUN   show
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show Substances known as non-creatinine chromogens are sometimes present in the blood; false elevated levels.  
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show muscle metabolism.  
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Creatinine is degradation product of   show
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show creatinine.  
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show equilibrate throughout body BUN about 1,5 hrs.  
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Specific Gravity Solute concentration Defined   show
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Measured by refractometer   show
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show tubular function.  
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Adequate concentration min SG that should occur with   show
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show > 1030.  
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show >1035.  
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show > 1025.  
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show SG = 1008-1012.  
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SG Solute concentration is similar to   show
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show sg.  
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show Unconcentrated.  
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show dilutional function.  
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show ALT, AST.  
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show SDH, AST, GGT.  
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show small animal.  
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show ALT.  
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show hepatocytes, muscle can infrequently contribute.  
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muscle contains modest amounts of   show
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show ALT.  
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mild to moderate muscle injurty unlikely to cause significant   show
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show ALT.  
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show severity or reversibility.  
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show Increased serum levels indicate cell injury cytosolic and mitochondrial.  
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AST highest values occur with severe   show
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High activity in liver and muscle   show
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high serum level can result from injury to either organ   show
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must be used in combo with other tests ALT, SDH, CK muscle   show
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show AST.  
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show AST.  
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SDH sorbitol dehydrogenase large and small increase indicates   show
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T 1/2 very short minutes to hours   show
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show SDH.  
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useful to follow progression   show
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helpful to determine if AST is increased because of muscle or liver injury   show
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GGT gamma glutamyltransferase large animal increase mainly due to   show
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T 1/2 = 3 days in horse   show
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show ALP, GGT, bilirubin, urine bilirubin.  
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show ALP > GGT > urine bilirubin > serum bilirubin.  
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show bound to hepatocellular membranes less in biliary cells chloestais marker.  
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T 1/2 dog = 3 days,cat = 6 hours,horse = between dog and cat, but more like cat   show
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Not liver specific   show
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found in liver   show
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show cALP in dog.  
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Drugs, steroids and anticuvulsants Phenobarbital   show
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Interpretation of increased ALP- dog general   show
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show hALP, cALP.  
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show pure cholestasis,pure isoenzyme induction corticosteroids, anticonvulsants,both cholestasis & isoenzyme induction.  
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must interpret ALP with other heptobiliary tests   show
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show any increase is significant =cholestasis.  
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show short.  
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Feline liver ALP activity is   show
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show inducible enzyme bound to membranes of bile duct epithelial cells and , to a lesser extent hepatocytes.  
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show GGT.  
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show cholestatsis, but may increase with acute, severe injury.  
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T 1/2 = 3 days in horses probably in dog and cat   show
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show less sensitive indicators of cholestasis than ALP, GGT.  
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show phagocytoses of senescent RBCs.  
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show heme and globin.  
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show amino acid constituents and recycled.  
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show unconjugated bilirubin.  
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show albumin and carried to liver.  
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conjugated by liver with glucuronic acid and excreted in   show
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show prehaptic, intrahepatic, or posthepatic causes.  
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show hemolysis increased RBC breakdown, 75 unconjugated.  
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show both conjugated and unconjugated bilirubin.  
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show 75 conjugated bilirubin.  
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urine bilirubin only conjugated bilirubin passes the   show
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show cholestasis.  
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dog normally renal threshold for bilirubin is   show
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cat high renal threshold urine bilirubin only present in   show
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show hepatic lipidosis or neoplasia OR vascular shunt that bypasses hepatocytes.  
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at least 70-80 of functional liver mass must be lost before signs and/or functional assays are altered   show
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decreased BUN as compared to creatinine which is often unaffected, unless animal has   show
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Can also see Decreased BUN with normal creatinine if   show
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dec albumin from dec synthesis OTHER DDx   show
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