Adaptability of the Nervous System
Quiz yourself by thinking what should be in
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on it to display the answer.
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show | Microvariations/error
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How do we learn a new movement | show 🗑
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show | In the central pattern generator
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show | Simplify the task into parts
Go slow/optimum speed
Co-contract the antagonist to stabilize
Limit variables/stimulus (clutter)
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What are the 5 main types of glia, and their function? | show 🗑
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show | occipital, parietal, temporal, frontal, limbic
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What are the 3 types of task practice, what kinds of activities are they good for training? | show 🗑
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show | The relay of info to the brain, regulation of vital functions like breathing, conciousness, and body temp
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What are the anterior and posterior sides of the spinal cord responsible for? | show 🗑
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show | higher cognitive function, attention, voluntary movement, planning, decision making
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What are the four areas of the frontal lobe? | show 🗑
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What is the temporal lobe concerned with? | show 🗑
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What is the parietal lobe concerned with? | show 🗑
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show | vital functions such as respiration and heart rate
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show | Relays info between the hemispheres and the cerebellum
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What are the two types of training scheduals? What are they good for? | show 🗑
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What is the limbic lobe responsible for? | show 🗑
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show | Block training, one activity at a time
Random taining, different following activities
Random is better, requires attention and concentration
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What is the thalamus responsible for? | show 🗑
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What is the hypothalamus responsible for? | show 🗑
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show | The biological clock
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Why can "kissing it better" or "rubbing it" make it better? | show 🗑
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show | thalamus, hypothalamus, pineal gland
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show | The pons, the medulla, the cerebellum, the spinal cord
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What are the two general principles of motor learning? | show 🗑
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What are the 7 key principles to Neuro placticity? | show 🗑
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show | The premotor cortex, supplemental motor area, basil ganglia, and cerebellum
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show | There are 12 pairs,31 pairs
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show | The more you practice the more you learn, repetition causes longterm changes
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show | Weakness causes a cycle of lack of use and weakness. Force them to use via contraint
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What are the two types of therapy? | show 🗑
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show | Gap junction-direct cell to cell (rare) Chemical synapse-across a synapse with neurotransmitters
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What produces myalin? | show 🗑
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show | Motivation-to keep trying
Attention-input specificity & cooperativity
Arousal-optimum amount
Memory-good & bad experiences
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What effect does MS have on the nervous system? | show 🗑
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show | Enviromental context,
The Task itself
Type of reinforcer
Practice schedual
Type of practice
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Mental rehersal is good for what kinds of activities? | show 🗑
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show | Action potential, calcium influx causes vessicles to releases neurotransmitter
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show | Open channels on the post synaptic side for ions to enter
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What determines if a neuron will achieve the threashold for an action potential | show 🗑
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What are the two forms of excitatory and inhibitory summation? | show 🗑
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show | Ligand channels-chemical
Voltage channels
G-protein- neurotransmitter causes distant channel to remain open. (changes cell structure)
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What are the three main types of neurotransmitters? | show 🗑
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What are three amino acid neurotransmitters? | show 🗑
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What are two common amine neurotrasmitters? | show 🗑
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show | Glycine-inhibitory
Glutamate-excitatory
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show | Placticity
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show | Lead to observable changes in the organism
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How does a neuron respond to increased receptor use/modulate gene expression? | show 🗑
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show | 1. Unmasking-minor inputs exaggerate
2. Dendritic pruning of unused dendrites
3. Collateral sprouting recieving new input from another axon
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What is the main mechanism for change in the brain? | show 🗑
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show | Increased activity, and vacancy
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What three areas in the brain experience neurogenisis? | show 🗑
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show | Proliferation
Migration
Differentiation
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What three cells can be created from a neural stem cell and what is most likely? | show 🗑
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show | Trouble synching with what's there
Abnormal connections
Differentiate mostly into astrocytes
Can cause cancers and neuromas
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What is the key component to motor learning? | show 🗑
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show | Relevant to the task, and properly timed
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show | The best long term generalizabiliy comes from self problem solving alone
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show | Only a little given when they are 90% accurate
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What is state dependent learning? | show 🗑
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show | Dendrites release neurotropins which can only be taken up by an axon that is experiencing action potentials
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show | Collateralization, Dendritic growth, number and activity of receptors, in summary the entire neuron
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The growing end of an axon is called what? | show 🗑
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show | Guiding cells
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Neurotropins may have what effect? | show 🗑
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What are 4 common guidence molecules? | show 🗑
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What happens to neurons that have been damaged? | show 🗑
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show | Behaviors & thoughts processes that are rewarded undergo neural structural changes
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What is hemoragic necrosis? | show 🗑
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show | A lack of oxygen to tissue
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What is transneuronal degeneration? | show 🗑
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show | A glial scar forms, followed by demylination of surrounding neurons
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show | A mechanical barrier separating damaged tissue and preventing neuronal growth
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show | CSPG, Semaphorin, Ephrin
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How quickly does a peripheral neuron regrow? What does this allow? | show 🗑
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What type of neurons regrow, which is fastest? | show 🗑
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What differences exist between the PNS and CNS in neural regeneration? | show 🗑
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What problems can occure with PNS regrowth? | show 🗑
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show | Glutamate is excitatory,
Glycine and Seratonin (5ht are inhibitory
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show | Oligodendricytes release inhibitors Astrocytes inhibit as glial scar
Small amount growth factors
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show | axon collateralization-use of cells to cause specialized change, use of concurrent systems,
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What is the difference between learning and memory? | show 🗑
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show | Pain is a learned association/perception of nocioceptor information
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What are the two types of memory? | show 🗑
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Where is declaritive memory located? | show 🗑
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show | Basal ganglia, striatum, cerebellum, amygdala
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What are the two types of non-declaritive memory? | show 🗑
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show | Associative, Non associative
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show | Single stimulus changing behavior Habituation Sensitization
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What is associative learning? what are two examples? | show 🗑
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show | 'A' Delta fibers-temp, deformation (sudden pain) 'C' Fibers-any kind of change (dull ache) 'A' Beta- Tactile/location
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show | Sensation of localized pain when non present (eg. touch a sunburn), Hypersensitivity to pain
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show | The foramen magnum, L1/ L2 Conus medularis
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show | Acute (sharp) Persistant (tissue damage) Chronic (unceasing despite no damage)
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How does the opiod system suppress pain? | show 🗑
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What does the anterior median fissure mark in the spinal column? | show 🗑
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Pain suppression cannot occure without what neurotransmitter? | show 🗑
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show | Myostatic reflex, 2-one afferent one efferent.
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show | Afferent information, Efferent
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show | unrelieved persistant pain despite no tissue damage
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What neurons convey from afferent to efferent neurons? | show 🗑
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Interneurons can be what two types? | show 🗑
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Why is surgery often ineffective at reducing pain? | show 🗑
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show | Loss of sensation and motor control in BOTH limbs
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show | An increase resistance in stretch reflex
An increase in tone
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Afferent fibers from the lower body to the upper body are laid down how in the spinal column? | show 🗑
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show | The Acending Lateral Spinothalamic tract
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What effect does habituation have on the nerve? | show 🗑
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What effect does sensitization have on the nerve? | show 🗑
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Diseases that cause spacticity usually have what 5 symptoms? | show 🗑
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What is the difference between habituation and Longterm Depression? | show 🗑
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show | Long term associative learning is structural changes(growth of new inputs), sensitization is just temporary
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show | Classical conditioning
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show | The unconditioned stimulus is the normal physiologic stimulus. Thu conditioned stimulus is the sensory stimulus unrelated to anything
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show | Because calcium is already going into the cell, while G-protiens are active, AMPA will go up increasing activity in the cell and cellular changes
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What is memory and learning? | show 🗑
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*****How does synaptic transmission/learning occur? | show 🗑
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show | Climbing fibers-transmit movement information
Mossy fibers transmit-the expected movement
perkinji fibers-Recieve signals from both and send error signals when they don't match
Parellel fibers-Learn and show plastic changes
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When does learning occure in the cerebellum occure and why? | show 🗑
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show | When the incomming stimulus is simultaneous
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What is the difference between declaritive and non declearitive memory? | show 🗑
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Describe the lateral spinothalamic tract and what information it carries: | show 🗑
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What is Hyperalgesia? What is Alhondonia? | show 🗑
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There are two meathods of long term potentiation/memory, what are they? | show 🗑
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Errors in learning/association are called what, and how do they occure? | show 🗑
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What three peripheral pain signals can be controlled and with what methods? | show 🗑
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How does longterm potentiation/memory occur in the hyppocampus? | show 🗑
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How can a depolarization cause longterm depression OR longterm potentiation? | show 🗑
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show | Kinase-memory, increase AMPA
Phosphatase-forgetting, decrease AMPA
It is this balance that causes longterm changes
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If a peripheral nerve is severed and has to regrow 1cm, how long will this take? | show 🗑
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show | The Posterior Column
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show | The motor cortical spinal tract
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What acending/decending area of the CNS nerves are particularly vulnerable to injury? | show 🗑
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show | Decussation of the pyramids
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Describe what the posterior column does and what kind of information it transmits: | show 🗑
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The cell bodies for the efferent neurons are where? | show 🗑
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show | dorsal root ganglion outside the spinal column
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Describe the posterior column and what information it carries | show 🗑
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show | Individual motor acts
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show |
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show | A poly synaptic reflex
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show | The Anterior spinothalamic tract
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Describe the Lateral Spinothalamic tract and what information it carries? | show 🗑
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show | Touch information, crosses in the spine, ascends to the Postcentral gyrus
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show | The lateral spinothalamic tract
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What pathway tranmits touch information? | show 🗑
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show | Reflexes: Simple automatic movements requiring no concious input
Reactions:complex movement requiring conciousness
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show | Position and movement of muscles up the same side of the body to the cerebellum
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show | Distributed control, thoughout the brain
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Complex motor reflexes and repetative rythmic movements are produced where? | show 🗑
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show | The posterior cerebellar tract and the cuneocerellar tract
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show | Premotor cortex, supplemental motor area, cerebellum
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show | Reticular formation
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show | Initiate and regulate movement at the central pattern generator
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Describe the Anterior and Rostral spinocerebellar tracts and what information they carry: | show 🗑
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show | coordination and sequencing of movement (smooth motion)
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Motor movement disorders often are a result of what? | show 🗑
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Discordinated movement and tremors is called what | show 🗑
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The fact that all systems are distributed, in the greater picture means what? | show 🗑
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show | Power, Accuracy, Speed
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How are accuracy and speed related? | show 🗑
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show | Peripheral:nocioceptor releases substance P, mast cells release histones- cause swelling. Histones+ swelling stimulate other nocioceptors. Synaptic: Glutamate + Substance P increase Post AMPA receptors making more likely to detect glutamate
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What are the two methods of down regulating pain? | show 🗑
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show | Voluntary motor control, decends from the Primary motor cortex, crosses at the decussion of pyramids in the medulla, stimulates the motor neuron
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show | Wheneverf a neuron is activated and makes a decision to fire
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show | the cortical spinal tract
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show | Signal-Decision to act-Plan-Program-Execution-Error detection and correction
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show | The plan-what kind of things they will do The program-what order and sequence of muscles used The execution-how fast, or force produced
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show | The thalamus-the PO region The lateral fissure-secondary sensory cortex
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show | Extrapyramidal pathway
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show | the spinal ganglia
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Where are the cell bodies of the motor neurons located? | show 🗑
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show | Voluntary motor movement
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What are terminal fibers? | show 🗑
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Mixed pathways/extra pyramidal pathways control what? | show 🗑
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show | Visual reflexes
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What does the accessory occular motor nuclei do? | show 🗑
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show | Midial longtitudinal and the Vestibulo pathways
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show | Spinal cord, medulla, pons, midbrain, dicephalon
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The cranial nerves are part of what structure? | show 🗑
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show | OLd OPie OCcasionally TRies TRIGonometry And Feels VEry GLOomy, VAGUe, And HYPOactive olfactory, optic, occular, trochlear, trigeminal, abducens, facial, vestibulocochlear, Vagus, Accessory, Hypoglossal
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What do legions to the anterior lobe of the cerebellum cause what? | show 🗑
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show | Respiratory and cardiac distress
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Legions to the neo-cerebellum cause what? | show 🗑
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show | Three major fiber tracts or peduncles
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show | Ponto cerebellar tract
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Lesion to the cyngulate gyrus cause what? | show 🗑
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Pain receptors use what kind of inhibitors? | show 🗑
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show | Sharp pain-delta fibers Prolongued burning pain-C fibers
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Pain afferent neurons release what neuro transmitter substance? | show 🗑
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show | The lateral spinothalamic tract
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Pain is inhibited by what areas of the brain first? | show 🗑
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What medications act as pain inhibitors? | show 🗑
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What natural substances are really effective at inhibiting pain? | show 🗑
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What cranial nerve is responsible for smell? | show 🗑
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What cranial nerve is responsible for vision | show 🗑
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What cranial nerve is responsible for eye movement? | show 🗑
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show | eye movements
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show | Trigeminal
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What is the abducens nerve responsible for? | show 🗑
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What nerve is responsible for facial, salivation and test? | show 🗑
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show | Vestibulocochlear
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The nerve responsible for the pharynx and larynx? | show 🗑
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show | Accessory nerve
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What cranial nerve stimulates the tongue? | show 🗑
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show | The medial, parietal, frontal brain, and corpus colossum
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What does the middle cerebral artery supply? | show 🗑
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show | the occipital lobe.
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show | The Anterior spinocerebellar tract-Lower body
The Rostral spinocerebellar tract-Upper body
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Describe the transmission of information in the 2 spinocerebellar tracts: | show 🗑
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show | Transmission from the primary motor cortex, information crosses in the medulla at the decussion of the pyramids and stimulates a motor neuron
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What are the two mixed spinal pathways and what do they do? | show 🗑
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show | crosses at midbrain, responsible for visual following
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Describe the Rubrospinal tract and what it is responsible for: | show 🗑
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show | The pontine reticulospinal tract-evervates the muscle spindle
The medullar reticularspinal tract inhibits smooth muscles
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What tract in the spine is responsible for voluntary motor control? | show 🗑
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What spinal tract is responsible for equalibrium righting reactions? | show 🗑
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What tract in the spine is responsible for individual motor acts? | show 🗑
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What tract is responsible for visual following? | show 🗑
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show | The rubrospinal tract
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What tract is responsible for enervating the muscle spindle? | show 🗑
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show | The medullar reticulospinal tract
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What are the 6 stages by which spacticity occurs? | show 🗑
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What are 4 best ways of managing spacticity and contractions? | show 🗑
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What is the most common problem with orthotics? | show 🗑
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show | Ligand gated sodium channels
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show | Collateral sprouting
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show | 1. Use it to impove it or lose it
2. Specificity vs. Transference
3. Repetition
4. Age=plasitc
5. Interference
6. Motivation&Expectation=improvement
7. Feedback is necessary
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