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Pharmacotherapy-II

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show iron def, anemia chronic dz, associated w/ acute blood loss  
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Symptoms of acute onset anemia   show
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show fatigue, weakness, HA, vertigo, faintness, sensitivity to cold, loss of skin tone pallor  
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show CBC w/ RBC, retic count, FOB  
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Nl ranges for Hgb and hematocrit   show
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Nl MCV   show
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show M: 45-160 F: 30-150  
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Nl ferritin   show
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show M: .5-1.5 F: .5-2.5  
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show Hgb synthesis therefore O2 transport  
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show inadequate dietary intake, inadequate aborption, ↑iron demands, blood loss, list some of each  
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What are signs of iron def   show
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Koilonychias   show
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show affects cognitive fxn and achievement  
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Lab findings with iron def anemia   show
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What ↑ absorption on nonheme iron   show
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What iron is more easily absorbed   show
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show milk and tea  
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show find underlying cause, dietary supplements, therapeutic iron preparations oral or paraenteral, transfusions  
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show max in duadnum, rest in small intestine ( don’t want extended release)  
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show 200mg elemental iron/day, in 2-3 doses (best absorbed w/o food or other meds)  
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When is iron better tolerated   show
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MC iron supplementation   show
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show GI, discoloration of feces (black), abd pain, heartburn, constipation, N/V  
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Absecence of AE’s may indicate what   show
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show take iron w/ meals (↓daily dose to 110-120mg elemental Fe)  
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Monitoring of iron supplementation   show
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show nonadhearence, misdiagnosis, malabsorption, blood loss, anemia-inducing dz states  
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What is the gold standard for parenteral iron supplementation   show
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show arthralgias, myalgias,flushing, malaise, fever, allergic rxns (rarely anaphylaxis)  
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What should we do prior to giving full iron dextrose dose   show
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show water soluble vitamin, obtained by ingestion of meat and dairy products,  
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show needed for DNA synthesis, metabolic rxns w/ folic acid,  
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show 2-2.6mg  
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show inadequate intake, ↓ absorption, inadequate utilization  
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s/s of B12 def   show
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lab findings of B12 def   show
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show Vit B12 def d/t intrinsic factor def  
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show oral (1-2mg), parenteral:1000mcg q week , nasal spray: do not administer within 1 hr hot food/beverage  
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monitoring of B12 def tx   show
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what may be greater during B12 initiation   show
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AE’s ofB12 tx   show
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Where can we find folic acid   show
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What is folic acid   show
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What are folate antagonists   show
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show inducers: phenytoin, phenobarbital, primidone  
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Sxs of folic acid def   show
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show 1-5mg po qdx4m  
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What is pre contraception for folic acid   show
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show within 2m  
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What is the anemia mechanism with anemia of chronic dz   show
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show may inhibit production or action of erythropoietin or inhibit RBC production  
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show serum iron ↓, ferritin nl or ↑, iron binding capacity nl or ↓  
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show tx underlyin d/o erythropoietin stimulating agents,  
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AE’s of erthyropoeitin   show
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Created by: becker15
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