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anti viral Test

Enter the letter for the matching action/type
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1.
DOC for RSV
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2.
Anti-viral with a dose limiting toxicity of pancreatitis
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3.
Valganciclovir
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4.
Saquinavir
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5.
Enfuvirtide
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6.
Trifluridine
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7.
ribivirin
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8.
Lamivudine
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9.
Adefovir
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10.
Ganciclovir
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11.
HIV med used to reduce transmission during birth
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12.
Famciclovir
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13.
DOC for influenza A
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14.
cidofovir
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15.
Amantadine and Rimantadine
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16.
DOC for CMV retinitis
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17.
stavudine
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18.
Pegylated interferon alpha
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19.
Antivirals that are teratogens
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20.
Antivirals associated with neutropenia
A.
rapidly metabolized in intestinal wall and liver to ganciclovir, indicated for the treatment of CMV retinitis
B.
Didanosine
C.
competitive inhibitor of reverse transcritase and a terminator of DNA chain elongation
D.
inhibits DNA synthesis; active against HSV1&2, vacinia, and some adenoviruses
E.
prodrug that is converted to penciclovir --> similar activity to acyclovir, used for HSV1&2, VZV, EBV, HBV
F.
Delavirdine, efavirenz, and ribavirin
G.
(blank)
H.
nucleotide analog, inhibits HBV DNA polymerase
I.
best tolerated protease inhibitor but least effective because of bioavailability
J.
reduced clearance and sustained absorption results in stedier drug concentration and less frequent doses
K.
blocks entry into cell, lacks cross resistance
L.
Ganciclovir
M.
cytosine nucleotide analog with invitro activity against CMV,HSV1&2, VZV, EBV, HHV6&8, adenovirus,poxvirus,polyomaviruses, and HPV; inhibits viral DNA
N.
Ganciclovir, zidovudine, saquinavir, and interferon
O.
amantidine
P.
inhibit uncoating of single stranded RNA viruses, used for influenza A
Q.
inhibits uncapping of viral messenger RNA, monotherapy not effective
R.
AZT
S.
inhibits replication of CMV; used to treat CMV retinitis, colitis, oresophagitis
T.
Ribavirin
Type the action/type that corresponds to the displayed Drug.
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21.
Indinavir
Type the CSF penetration that corresponds to the displayed Drug.
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22.
SE for ganciclovir
Type the side effects/contraindications that corresponds to the displayed Drug.
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23.
HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism
Type the protein binding that corresponds to the displayed Drug.
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24.
Delavirdine
Type the protein binding that corresponds to the displayed action/type.
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25.
competitivly inhibits HIV reverse transcriptase
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26.
prodrug converted rapidly and completely to acyclovir
Type the elimination that corresponds to the displayed bioavailability/absorption.
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27.
oral bioavilability good, not food dependant
Type the protein binding that corresponds to the displayed CSF penetration.
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28.
some CNS penetration
Type the CSF penetration that corresponds to the displayed side effects/contraindications.
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29.
diarrhea and flatulence
Type the protein binding that corresponds to the displayed side effects/contraindications.
incorrect
30.
nausea, vomiting headache, crystalline nephropathy or neurotoxicity

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