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Stack #181450
GI Meds
Question | Answer |
---|---|
CALCIUM CARBONATE | Tums-calcium containing antacid |
Antacids MOA | ACT TO NEUTRALIZE ACID IN THE STOMACH (raise the PH)PROMOTE GASTRIC MUCOSAL DEFENSIVE MECHANISM BYSTIMULATING MUCUS, PROSTAGLANDIN & BICARBONATE SECRETION FROM GASTRIC CELLS |
Antacid Side effects,MAGNESIUM PREPARATIONS | DIARRHEATOXICITYUSE WITH EXTREME CAUTION IN PATIENTS WITH RENAL FAILURE (difficult to excrete) |
CALCIUM PREPARATIONS Antacid side effects | REBOUND HYPERACIDITY |
Aluminum & Calcium Antacid side effects | Constipation |
Cimetidine | Tagament-H2 Antagonist |
Famotidine | Pepcid-H2 Antagonist |
Ranitidine | Zantac-H2 Antagonist |
4 things that defend stomach lining | mucus, bicarbonate, good blood flow, and prostaglandins |
H2 Antagonists | block H2 receptors of acid producing cells (suppress acid production) |
Therapeutic uses of H2 antagonists | Gastric ulcers, GERD,Hypersecretory conditions (stress), Duodenal ulcers, Upper GI bleeds |
Adverse effects of Cimetidine (Tagement) | Impotence and Gynecomastia |
Proton Pump Inhibitors (PPIs) | prevents proton pump from moving hydrogen ions out of parietal cells and into the stomach; blocks all acid secretion |
Esomeprazole | Nexium -PPI |
Lansoprazole | Prevacid- PPI |
Omeprazole | Prilosec-PPI |
Therapeutic uses of PPIs | GERD, Erosive esophagitis, duodenal ulcers, active gastric ulcers |
Sucralfate (Carafate) | cytoprotective agent (mucuosal protectant), forms protective barrier over ulcers and limits access of pepsin and gastric acid to these ulcers |
Therapeutic uses of Sucralfate (Carafate) | Stress ulcers, Erosions, Peptic Ulcer disease |
ALUMINUM HYDROXIDE | Amphojel |
Docusate Sodium (Colace) | Surfacant Laxative-Stool softnerwetting agent to soften stool |
Psyllium (Metamucil) | Bulf forming laxativeabsorbs water to increase bulk |
Senna (Senokot) | Stimulant laxativeincreases peristalsis via nerve stimulation in the colon |
Magnesium hydroxide (MOM) | Osmotic laxativeincreases water content of stool |
Adverse effect of stool softners | Abdominal cramping |
Adverse effect of bulk forming laxatives | Gas formation |
Adverse effect of stimulant laxatives | Malaborption |
Adverse effect of osmotic laxatives | Electrolyte imbalance (dehydration) |
Promethazine (Phenergan) | Antiemetic-antihistimine, blocks histamine receptors |
Therapeutic uses of Promethazine (Phenergan) | Motion sickness, N/V |
Ondansetron (Zofran) | Antiemetic-serotonin blocker, blocks serotonin receptors in GI tract and vomiting center in the medulla |
Therapeutic uses of Ondansetron (Zofran) | N/V associated with Chemotherapy and post op |