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Med. Chem.
Med. Chem. Spring Final 2005
Drug Name | Chem Class | Pharm Class | MOA |
---|---|---|---|
Cocaine | Tropane derivative | Local anesthetic/CNS stimulant | Blocks Na channels/inhibits DA uptake |
Benzocaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Procaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Tetracaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Butamben | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Propoxycaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Chloroprocaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Proparacaine | Aminobenzoic ester | Local anesthetic | Blocks Na channels |
Dibucaine | Amide | Local anesthetic | Blocks Na channels |
Bupivacaine | Amide | Local anesthetic | Blocks Na channels |
Lidocaine | Amide | Local anesthetic | Blocks Na channels |
Prilocaine | Amide | Local anesthetic | Blocks Na channels |
Mepivacaine | Amide | Local anesthetic | Blocks Na channels |
Etidocaine | Amide | Local anesthetic | Blocks Na channels |
Ropivacaine | Amide | Local anesthetic | Blocks Na channels |
Dyclonine | Amino ketone | Local anesthetic | Blocks Na channels |
Pramoxine | Amino ether | Local anesthetic | Blocks Na channels |
Fludrocortisone acetate | Steroid | Mineralocorticoid | Mediates Na/K exchange-inc. Na reabsorbtion |
Cortisone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Hydrocortisone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Corticosterone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Prednisone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Betamethasone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Dexamethasone | Steroid | Systemic glucocorticoid | Inhibits arachidonic acid release |
Clobetasol propionate | Steroid | Topical glucocorticoid | Inhibits arachidonic acid release |
Flucinolone acetonide | Steroid | Topical glucocorticoid | Inhibits arachidonic acid release |
Fluticasone propionate | Steroid | Topical glucocorticoid | Inhibits arachidonic acid release |
Triamcinolone acetonide | Steroid | Topical glucocorticoid | Inhibits arachidonic acid release |
Testosterone | Steroid | Androgen | Testosterone agonist |
Methyltestosterone | Steroid | Androgen | Testosterone agonist |
Fluoxymesterone | Steroid | Androgen/anabolic | Testosterone agonist |
Stanozolol | Steroid | Anabolic steroid | Testosterone agonist |
Oxandrolone | Steroid | Anabolic steroid | Testosterone agonist |
Nandrolone decanoate | Steroid | Anabolic steroid | Testosterone agonist |
Finasteride | Steroid | Androgen hormone inhibitor | Inhibits 5a-reductase |
Dutasteride | Steroid | Androgen hormone inhibitor | Inhibits 5a-reductase |
Estradiol cypionate | Steroid | Estrogen | Estrogen agonsim |
Estropipate | Steroid | Estrogen | Estrogen agonism |
Ethinyl estradiol | Steroid | Estrogen | Estrogen agonism |
Anastrozole | Triazole | Anti-estrogen | Reversibly inhibits aromatase |
Letrozole | Triazole | Anti-estrogen | Reversibly inhibits aromatase |
Exemestane | Steroid | Anti-estrogen | Irreversibly inhibits aromatase |
Clomiphene | Stilbenediol | Anti-estrogen | Increases gonadotropin secretion |
Tamoxifen | Stilbenediol | Anti-estrogen | Rev. estrogen receptor antag. |
Toremifene | Stilbenediol | Anti-estrogen | Rev. estrogen receptor antag. |
Raloxifene | Misc. | Anti-estrogen | Sel. estrogen receptor modulator |
Norethindrone | Steroid | Progestin | Inhib. FSH/LH release |
Norgestrel | Steroid | Progestin | Inhib. FSH/LH release |
Levonorgestrel | Steroid | Progestin | Inhib. FSH/LH release |
Desogestrel | Steroid | Progestin | Inhib. FSH/LS release |
Progesterone | Steroid | Progestin | Progestin agonist |
hydroxyprogesterone caproate | Steroid | Progestin | Progestin agonist |
Medroxyprogesterone acetate | Steroid | Progestin | Progestin agonist |
Megesterol acetate | Steroid | Progestin | Progestin agonist |
Mifepristone | Steroid | Antiprogestin | Progestin antagonist |
Tolbutamide | Sulfonylurea | Hypoglycemic | Stimulates insulin release |
Tolazamide | Sulfonylurea | Hypoglycemic | Stimulates insulin release |
Acetohexamide | Sulfonylurea | Hypoglycemic | Simulates insulin release |
Chlorpropamide | Sulfonylurea | Hypoglycemic | Stimulates insulin release |
Glyburide | Sulfonylurea | Hypoglycemic | Simulates insulin release |
Glipizide | Sulfonylurea | Hypoglycemic | Stimulates insulin release |
Glimepiride | Sulfonylurea | Hypoglycemic | Simulates insulin release |
Metformin | Biguanide | Hypoglycemic | Increases glucose uptake |
Acarbose | Carbohydrate | Hypoglycemic | Inhibits a-glucosidase |
Miglitol | Carbohydrate | Hypoglycemic | Inhibits a-glucosidase |
Rosiglitazone | Thiazolidinedione | Hypoglycemic | Activate PPAR |
Pioglitazone | Thiazolidinedione | Hypoglycemic | Activate PPAR |
Repaglinide | Misc. | Hypoglycemic | Stimulates insulin release |
Nateglinide | Misc. | Hypoglycemic | Stimulates insulin release |
Glucagon | Peptide | Glucose elevating agent | Simulates glycogenolysis |
Diazoxideoral | Benzothiadiazine | Glucose elevating agent | Inhibits insulin release |
Sulfadiazine | Sulfonamide | Antibacterial | Inhibits dihydropteroate synthase |
Silver sulfadiazine | Sulfonamide | Antibacterial | Inhibits dihydropteroate synthase |
Sulfasalazine | Sulfonamide | Antibacterial | Inhibits dihydropteroate synthase |
Sulfisoxazole | Sulfonamide | Antibacterial | Inhibits dihydropteroate synthase |
Sulfamethoxazole | Sulfonamide | Antibacterial | Inhibits dihydropteroate synthase |
Trimethoprim | Pyrimidinediamine | Antibacterial | Inhibits dihydrofolate reductase |
Nalidixic acid | Quinolone | Antibacterial | Inhibits DNA gyrase |
Cinoxacin | Quinolone | Antibacterial | Inhibits DNA gyrase |
Norfloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Ciprofloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Ofloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Lomefloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Enoxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Levofloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Sparfloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Gatifloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Moxifloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Trovafloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Alatrovafloxacin | Fluoroquinolone | Antibacterial | Inhibits DNA gyrase |
Amantadine | Adamantane | Antiviral | Inhibits host cell penetration by virus |
Rimantadine | Adamantane | Antiviral | Inhibits viral uncoating |
Oseltamivir | Misc. | Antiviral | Inhibits neuraminidase |
Zanamivir | Misc. | Antiviral | Inhibits neuraminidase |
Ribavirin | Pryimidine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Amprenivir | Misc. | Antiviral | Protease inhibitor |
Saquinavir | Misc. | Antiviral | Protease inhibitor |
Indinavir | Misc. | Antiviral | Protease inhibitor |
Ritonavir | Misc. | Antiviral | Protease inhibitor |
Nelfinavir | Misc. | Antiviral | Protease inhibitor |
Abacavir | Purine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Didanosine | Purine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Lamivudine | Pyrimidine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Stavudine | Pyrimidine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Zalcitabine | Pyrimidine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Zidovudine | Pyrimidine nucleoside | Antiviral | Comp. inhibits HIV-1 reverse transcriptase |
Delavirdine | Misc. | Antiviral | Non-comp. inhibits HIV-1 reverse transcriptase |
Efavirenz | Misc. | Antiviral | Non-comp. inhibits HIV-1 reverse transcriptase |
Nevirapine | Misc. | Antiviral | Non-comp. inhibits HIV-1 reverse transcriptase |
Acyclovir | Purine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Vidarabine | Purine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Famciclovir | Purine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Valacyclovir | Purine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Ganciclovir | Purine nucleoside | Antiviral | Inhibits viral DNA polymerase |
Trifluridine | Pyrimidine nucleoside | Anitviral | Inhibits thymidylate synthetase |
Foscarnet sodium | Phosphate | Antiviral | Inhibits viral DNA polymerase |