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ASCP Hematology
| Question | Answer |
|---|---|
| Wright's stain, Schuffner's dot, parasites with irregular "spread-out" trophozoites | Plasmodium vivax |
| RBC erroneously increased | decreased MCH |
| glucocerebrosidase deficiency | Gaucher's disease |
| disease most closely associated with cytoplasmic granule fusion. | Chediak-Higashi syndrome |
| disease most closely associated with mucopolysaccharidosis. | Alder-Reilly anomaly |
| characteristic morphologic feature in folic acid deficiency | macrocytosis |
| differentiate leukomoid reactions vs chronic granulocytic leukemias | leukocyte alkaline phosphatase |
| Terminal deoxynucleotidyl transferase (TdT) is marker found on: | lymphoblasts |
| leukocyte alkaline phosphatase activity is increased in: | leukemoid reaction |
| ALL, the acid phosphatase stain is usually positive for: | T cell ALL |
| PB monocyte is an intermediate stage for | histiocyte |
| characteristic of Auer rods | lysosome and acid phosphate positive |
| precursors of tissue macrophages | monocytes |
| stain for evaluation of BM | Romanowsky and Prussian blue stain |
| atypical lymphocyte seen in the perismear of patient with IM. | T lymphocytes |
| platelet aggregation will occur with the end production of: | thromboxane A2 |
| megaloblastic asynchronous development in the BM indicate | impaired synthesis of DNA |
| type of leukemia seen most commonly as a terminal event in multiple myeloma | acute myelogenous leukemia |
| occur in the presence of cold agglutinin | increased MCV and decreased RBC |
| EDTA, RT at 6-24hrs | increased hematocrit and MCV |
| substrate used to detect specific esterase | chloroacetate |
| characteristic of Factor XII deficiency | negative bleeding history |
| most closely associated with chronic myelomonocytic leukemia | lysozymuria |
| most closely associated with erythroleukemia | ringed sideroblasts |
| Vitamin-K dependent | Factor VII |
| mean value of a reticulocyte on cord blood | 5 % |
| hypercellular marrow with an M:E of 6:1 | granulocytic hyperplasia |
| B cell origin | Waldenstroms macroglobulinemia |
| most closely associated with megaloblastic anemia | neutropenia and thrombocytopenia |
| most useful in differentiating hemophilia A and B. | mixing studies |
| most closely associated with idiopathic hemochromatosis | iron overload in tissue |
| seen most often in thalassemia | target cells |
| use to stain neutral fats, phospholipids, and sterols | Sudan Black B |