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Ch.13

Pharamcodynamics

TermDefinition
What is Pharmacodynamics? A subset of pharmacology that deals with how medications cause their effects on the body
What are the 3 concepts addressed in Pharmacodynamics? Mechanism of action(Agonist/Antagonist), Therapeutic Window, Therapeutic Index
What is an example of an agonist? Albuterol stimulates Bronchiole DILATION to help asthma patients breathe better
What is an example of an antagonist? Metoprolol inhibit the stimulation of the heart to decrease cardiac output
What is an agonist? A medication that stimulates the effects of an existing process?
What does a wide therapeutic window indicate? A medication with a greater range of doses that will work for patients
How is the therapeutic index value determined? By taking a toxic dose of the medication and dividing it by the effective dose
What does a high therapeutic index value indicate? Medications with a higher TI are safer
What is an example of a medication with a high therapeutic index? Ibuprofen
What is an example of a medication with a low therapeutic index? Phenytoin
Created by: user-1773160
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