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M Antagonist

QuestionAnswer
Atropine Anti-Muscarinic Drugs
Xerostomia dry-mouth
M1 Salivation in Salivary glands, Enhanced cognition in the CNS.
M2 BradyCardia.
M3 Increased tone and motility, miosis, contraction of the detruser muscle in the bladder, Tearing.
Oxybutynin Can decrease the incidence of urinary urgency, urinary frequency, and urge incontinence.
Darifenacin Greatest M3 activation, Used for OAB (Overactive Bladder).
Solifenacin Solifenacin [VESIcare] is very similar to darifenacin, although it's not quite as M3 selective.
Tolterodine Nonselective muscarinic antagonist approved only for OAB.
Fesoterodine Nonselective muscarinic antagonist very similar to tolterodine.
Trospium Nonselective muscarinic blocker indicated only for OAB.
Scopolamine Atropine produce mild CNS excitation, therapeutic doses of scopolamine produce sedatio, suppresses motion sickness and emesis.
Ipratropium bromide Inhaled, anticholinergic drug used to treat asthma, chronic obstructive pulmonary disease, and rhinitis caused by allergies or the common cold.
Antisecretory anticholinergics Safer drugs available, can be used to suppress gastric acid secretion.
Dicyclomine This drug is indicated for irritable bowel syndrome.
Pirenzepine and telenzepine NOT FOUND IN THE U.S., Produce selective blockade of M1-muscarinic receptors
Mydriatic cycloplegics Atropine, ho–matropine, scopolamine, cyclopentolate, and tropicamide
Created by: ekm
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