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Med-surge Immunology
Immunology Lecture
Question | Answer |
---|---|
Which of the following substances is produced by plasma cells (mature B cells)? | immunoglobulins |
The cell markers present on the surface of all cells that indicate "self" or "non-self" are called | epitopes |
The classification of immunoglobulin responsible for allergic reactions by stimulating Mast Cells to release histamine is | IgE |
The primary immune system organ which produces stem cells, many of which will eventually mature into various types of lymphocytes, is(are) the | bone marrow |
The chemical message substances released from Helper T cells which not only regulate B cell maturation and proliferation, but also differentiation of immature T cells into mature cytotoxic and regulatory T cells are | lymphokines |
Type IV - Delayed Hypersensitivity | Contact dermatitis for latex, adhesive, topical medication, or cosmetic sensitivity |
Type III - Immune Complex Disease | Acute inflammation and local tissue damage due to the clumping of normally circulating antigen-antibody complexes. Ex: systemic lupus erthematosus |
Type I - Immediate/Allergic | Typical allergic reactions such as hay fever. May result in anaphylaxis |
Type II - Cytotoxic Reactions to Self | The body's own tissue is recognized as foreign and the immune system is activated. Results in slow destruction of cellular membranes of normal tissues. Ex: blood transfusion reactions, myasthenia gravis |
The most appropriate position to place a person in if he/she is experiencing anaphylatic shock is | supine with feet elevated |
Passive Natural Immunity | D. Transplacental, colostrum, and/or breast milk antibody exposure from mother to fetus/baby |
Passive Artificial Immunity | Inoculation of antibody or antitoxin |
Active Natural Immunity | Natural contact and infection with an antigen (environmental exposure) |
Active Artificial Immunity | Inoculation of antigen (vaccination); live or dead antigen |
antigen | Any foreign substance in the body that does not have the characteristic cell surface markers of that individual and is capable of eliciting an immune response |
The neuroendrocrine organ essential for regulation of the immune system is the | Pituitary |
The immune organ where T cells differentiate from their origin of lymphoid stem cells and mature is(are) the | thymus |
Primary organs of the immune system | bone marrow and thymus |
secondary organs of the immune system | lymph nodes, spleen, tonsils, adenoids, appendix |
Tissues of immune system | peyers patches |
cells of immune system | luekocytes, lymphocytes (NK cells), other phagocytes |
granulocytes | neutro-, eosino, baso-phils |
the _____ filters and destroys old RBCs | spleen |
What is the spleens immune role? | filters blood antigens |
monocytes produce what | macrophages |
______ bring in Ag thru the blood to the spleen | macrophages |
the spleens ______ destroy antigens | T cells |
the spleen's ______ produce and antibody vs the antigen | B cells |
mature B cells differentiate into | plasma cells |
any substance capable of triggering an immune response is a _______ | antigen |
epitopes- | anything on the antigen that the antibody identifies and attaches to |
what happens if an epitope is misinterpreted where self is identified as nonself | auto immune disease |
proteins present on the surface of all cell bodies | self markers/ MHC |
what allows the immune system cells to recognize and communicate with one another? | MHC |
growth and reproduction of stem cells are controlled by proteins called: | growth inducers and differentiation inducers |
the most numerous of WBCs; die after phagocytosis and contribute to pus formation | neutrophils |
These cells clean up after neutrophils and kill any damaged but not dead backteria or too large for neturophils | monocytes |
weak phagocytes that participate in allergic disorders; destroy parasites | eosinophils |
histamine is produced by what cells | basophils |
basophils- | similar to mast cells; produce histamine; |
NK cells are what type | lymphocytes |