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DiureticDrugs

QuestionAnswer
Action of Diuretics (1) treatment of hypertension and (2) mobilization of edematous fluid associated with heart failure, cirrhosis, or kidney disease. In addition, because of their ability to maintain urine flow, diuretics are used to prevent renal failure.
Classification of Diuretics (1) high-ceiling (loop) diuretics (eg, furosemide); (2) thiazide diuretics (eg, hydrochlorothiazide); (3) osmotic diuretics (eg, mannitol); and (4) potassium-sparing diuretics.
potassium-sparing diuretics subdivision aldosterone antagonists (eg, spironolactone) and nonaldosterone antagonists (eg, triamterene)
High-ceiling diuretics drugs Furosemide (Laxic), Ethacrynic acid, Bumetanide, Torsemide
When is Furosemide used? (1) pulmonary edema associated with congestive heart failure (CHF); (2) edema of hepatic, cardiac, or renal origin that has been unresponsive to less efficacious diuretics; and (3) hypertension that cannot be controlled with other diuretics.
Adverse effects of furosemide Hypokalemia, hypotension, ototoxicity, hyperglycemia, hyperuricemia, bad for pregnancy
Furosemide impact on lipids, calcium, and magnesium Furosemide reduces high-density lipoprotein (HDL) cholesterol and raises low-density lipoprotein (LDL) cholesterol and triglycerides; increases urinary excretion of magnesium, increases urinary excretion of calcium.
Lithium and Furosemide Lithium treats bipolar, and sodium retention causes lithium retention.
NSAID and Furosemide NSAID decrease effects of Furosemide
Thiazides same as highloop, less urine output, PROMOTES RETENTION OF CALCIUM
Effects of low magnesium muscle weakness, tremor, twicthing, dysrhytmias
Thiazide Drugs Chrorothiazide, Hydrochlorothiazide, Methylclothiazide. Related Drugs: Chlorthalidone, Indapamide, Metolazone
Aldosterone antagonist drug Spironolactone
Two nonaldosterone antagonists triamterene and amiloride
Created by: ekm
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