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Pharm1152 Vit/Min/Sp
Vitamins, Minerals, Supplements
Question | Answer |
---|---|
Fat Soluble Vitamins | A,D,E and K |
Source of fat soluble vitamins | plants/animals |
Where are fat soluble vitamins stored? | liver and fatty tissues |
Where are fat soluble vitamins excreted? | Feces |
Water Soluble Vitamins | B-Complex and C |
If these vitamins are not taken in daily, a deficiency results | Water Soluble |
RDAs (Recommended Daily Allowances) | Minimum nutrient requirements |
DRIs (Daily Reference Intakes) | Optimal nutrient amounts for good health |
Vitamin A mechanism of action | Vision, G&D of bones & teeth,reproduction, mucosal & epithelial integrity, cholesterol & steroid synthesis |
Vitamin A toxicty | Irritability, drowsiness, vertigo, S&S of increased intracranial pressure in infants, redness& peeling of skin |
Indications of Vitamin A | Infants, pregnancy or nursing women, treatment of acne,psoriasis |
Vitamin D AKA ? | Sunshine Vitamin |
Vitamin D mechanism of action | Regulates absorption/use of calcium and phosphorus, neccessary for calcification of bone and regulates serum calcium levels |
Vitamin D Indications | Treatment of Rickets, Hypocalemia, hypophospatemia, osteoporosis |
Ricket's disease | Vit D deficiency- causes soft,pliale bones; bowlegs & knock knees and oth S |
Vitamin E mechanism of action | Powerful biologic antioxidant; hinder deterioration of Vit A & Vit C that are highly oxygen sensitive/readily oxidized |
Vitamin E indications | Antioxidant; prevention formation of toxic chemical in body |
Vitamin K is the antedote for ? | bleeding excessivley (Warfarin) |
Vitamin K mechanism of action | essential for blood coagulation factors (II,VII,IX,& X)in liver |
Vitamin K indications | inadequate dietary intake (rare) Malabsorptive states, administration of broad spectrum antibiotics |
Vitamin K is given to ? for malabsorption | newborns |
Vitamin B1 AKA | Thiamine |
Vitamin B1 deficiency | Beriberi |
Vitamin B1 mechanism of action | essential for CHO metabolism, Kreb's Cycle and oth metabolic pathways |
Vitamin B1 indications | Beriberi, Wernickes encephalopathy (cerebral Beriberi), Neuriti assoc with pellagra and pregnancy, malabsorption associated with cirrhosis, alcoholism & GI disease |
what is pellagra | niacin deficiency |
Vitamin B2 AKA | Riboflavin |
Vitamin B2 mechanism of action | Converts into enzymes needed for tissue respiration, activates B6, converts tryptophan into niacin, needed for erythroctye integrity |
Indications of Vitamin B2 | Treatment of deficiency (cutaneous,oral & corneal changes)Microcytic anemia, acne, migraines |
Adverse effects of Vitamin B2 | Changes urine yellow-orange in large doses |
Vitamin B3 AKA | Niacin |
Vitamin B3 mechanism of action | converts to 2 coenzymes required for glycogenolysis (breakdown of store glycogen into usable glucose)and lipid, protein and purine metabolism |
Indications of Vit B3 | Prevention and treatment of pellagra, management of hyperlipidemia and positive effect in PVD |
Contraindications of Vit B3 | Liver disease, severe hypotension, arterial hemorrhage & PUD |
Adverse effects of Vit B3 | Flushing, pruritus and GI distress; often subside when discontinued |
Vitamin B6 AKA | Pyridoxine |
Vitamin B6 deficiency | types of anemias, neurologic disturbances, skin and mucosa changes, etc |
Vitamin B6 mechanism of action | needed for protein, lipid, CHO utilization, conversion of tryptophan to niacin, needed for integrity of peripheral nerves, skin, muscoa, hematopoietic system |
Vitamin B6 indications | treatment of deficient caused by Isonazid (TB med) hydralazine (HTN med) and oral contraceptives- Can help with seizures, morning sickness |
Vitamin B6 toxicity | Only with large doses= neurotoxicity |
Vitamin B12 AKA | Cyanocobalamin |
Vitamin B12 deficiency | GI lesions, neurologic changes |
Major cause of Vit B12 deficiency | Malabsorption |
Vitamin B12 mechanism of action | Synthesized in body for Fat, CHO & protein synthesis, growth, cell replication, hematopoeisis and myelin synthesis |
Vitamin B12 indications | treatment of deficiency; pernicious anemia (lack of intrinsic factor) |
Contraindications of Vitamin B12 | Cobalt, Leber's disease (hereditary optic nerve atrophy) |
Vitamin C AKA | Ascorbic acid |
Vitamin C deficiency | scurvy (weakness, edema, gingivitis & bleeding gums, tooth loss, anemia, delayed healing of bones and tissues, etc) Sailors! |
Vit C mechanism of action | Involved in oxidation-reduction reactions, collagen synthesis, maintenance of connective tissue, bone, teeth and capillaries, folic acid metab, erythropoiesis |
Vit C indications | Treatment of deficiency, benefit for pregnancy, lactation, fever, stress, infcection, skin issues, colds, etc |
Adverse effects of Vit C | Large doses can cause N/V, HA, cramping, urine acidity, renal stones. can interfere with PCN G, erythromycin,; can enhance or delay excretion of acidic drugs |
Vitamin C + Zinc help with.... | healing |
Calcium | most abundant mineral, high conc in bones and teeth |
What facilitates calcium's absorption? | Vit D |
Calcium deficiency | Ricket's, osteoporosis, etc |
Calcium mechanism of action | needed for nervous, muscular, skeletal systems, cell membranes and capillary permeability, enzymatic reactions- nutritional supplement |
Indications of calcium | Treatment of conditions assoc with calcium deficiency |
Calcium contraindications | allergy, hypercalcemia, ventricular fib |
Calcium toxicity | long-term excessive use can lead to cardiac irregularities, dilirium, coma |
Magnesium is reponsible for ? | Muscle contractions |
Magnesium | one of the principle cations of intracellular fluid |
Magnesium mechanism of action | Needed for enzyme system assoc with energy metabolism, nerve physiology, and muscular contraction |
Magnesium indications | treatment of deficiency, complications of pregnancy, inhibition of contractions, cardiac dysrhythmias,constipation |
Magnesium contraindications | allergy to magnesium, heart block, renal failure, Addison's disease (adrenal gland failure), hepatitis |
Magnesium adverse effects | Loss of tension, relfex, difficult BMs, CNS depression, resp distress, heart block, hypothermia |
Phosphorus deficiency | can occur w/malabsorption, excessive diarrhea or vomiting, hyperthyroidis, long term use of aluminumor calcium antacids, liver disease |
Phosphorus mechanism of action | required for synthesis of essential body chemicals; building block for body structures |
Phosphorus indications | deficiency of phosphorus, nutritional supplement |
Phosophorus contraindications | hyperphosphatemia and hyopcalemia |
phosphorus adverse effects | N/V/D confusion, weakness, breathing difficulties; antacids can reduce the absorption of phosphorus |
Zinc | healing growth and repair |
Zinc mechanism of action | essential protein and CHO metabolic reactions; important for normal tissue growth & repair and wound repair |
Enteral nutrition- what to do when diarrhea occurs? | break down, 1/2 strength until body adjusts |
Enteral nutrition mechanism of action | formulas used provide basics for anabolism (tissue building) |
Dumping syndrome | secondary to rapid or bolus feeding |
Peripheral parental nutrition | arm/other for those unable to tolerate oral or enteral intake; temp method (less than 2 weeks) |
Central parental nutrition | Central circulation for those unable to tolerate oral or enteral intake; potential for infection |
Which lab needs to be checked every 6hrs with a Central line? | Glucose |