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Pharmacology
Autonomic Nervous System
Question | Answer |
---|---|
Parasympathetic nervous system's neurotransmitter | Acetylcholine |
Symapthetic nervous system's neurotransmitters | epinephrine, norepinephrine, and dopamine |
Adrenergic agonists act directly on the SNS by | 1. direct receptor binding to organs or tissues 2. promotion of norepi release 3. mimicking the action of norepi or epi |
4 main receptor types | alpha 1, alpha 2, beta 1, beta 2, and recently a beta 3 has been identified |
Alpha 1 receptors are mostly associated with | excitation or stimulation |
Alpha 2 receptors are mostly associated with | relaxation and inhibition of epi |
Beta 1 receptors are found mostly in the | heart brain, kidney, lipocytes |
Beta 2 receptors are located in the | smooth muscle of the eye, arterioles, venules, bronchioles, liver, pancreas, GI and GU tracts |