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CH 17 Vocab
Exam 2
Question | Answer |
---|---|
An arrest in the cell cycle for repair | Check point |
Encodes gene products that inhibit unregulated cell division. Mutant alleles function recessively in promotion of a cancerous phenotype in a cell | Tumor suppressor gene |
Molecule that affects cell proliferation. Generally stimulate proliferation by associating with receptor proteins on the affected cell | Growth factor |
Programmed cell death in which the cell coordinates its own DNA degradation and nuclear condensation | Apoptosis |
Normal gene regulating cell proliferation that can become an oncogene when mutated | Proto-oncogene |
Steroids, peptides, and proteins that act over short and long distances to provide extracellular signals to cells. | Hormones |
Proteins that underlie the inner surface of the nuclear membrane and become soluble during mitosis to allow dissolution of the nuclear membrane into vesicles | Nuclear lamins |
The relaying of a signal through the cytoplasm to the nucleus in order to mediate a cellular response to an extracellular signal. | Signal transduction |
A family of proteins that phosphorylate specific substrates in response to a cell-cycle dependent association with specific cyclins. | Cyclin-dependent kinase |
Mutant allele of a proto-oncogene that acts dominantly to promote a cancerous phenotype | Oncogene |