click below
click below
Normal Size Small Size show me how
Anti-hypertensive
Anti-hypertensive drugs
Common diuretics | Thiazide, Loop diuretics, K+ Sparing |
Example of Thiazide | Hydrochlorothiazide |
Example of loop diuretic | Furosemide |
Example of K+ Sparing | Spironolactone |
ACE Inhibitors | Captopril, lisinopril, ramipril, enalopril |
Angiotensin receptor blocker | Losartan, Valsartan, Telmisartan |
Direct Renin Inhibitor | Alliskiren |
Beta-adrenergic blocker [Non-selective] | Propranolol, pindolol, labetolol |
Beta-adrenergic blocker [Cardioselective] | Metaprolol, esmolol, betaxolol |
Beta-Alpha adrenergic blocker | Labetolol, Carvedilol |
Selective Aplha-1 adrenergic blocker | Prazosin, Doxazosin |
Agents that prevent adrenergic transmission | Reserpine, Guanadrel |
Centrally Acting | Clonidine, Methyldopa |
Calcium channel blockers | Diltiazem, Verapamil, Felodipine |
Potassium channel activator | Nicorandil, Diazoxide |
Vasodilators [Arterial] | Hydralazine |
Vasodilator [Arterio-venular] | Potassium Nitroprusside |
Indication for ACEI/ARB | Acute Myocardial Infarction, Hypertension, Heart Failure, Cardiovascular protection Nephropathy |
Adverse Effects of ACEI/ARB | Hypotention, Renal failure, Cough, Hyperkalemia,Skin reaction |
Contraindication of ACEI/ARB | Pregnancy, Pre-existing hypotension, hyperkalemia, bilateral renal artery stenosis |
Beta-1 adrenergic receptor | Located in the heart |
Beta-2 adrenergic receptor | Located in smooth muscles of bronchioles, arterioles, and visceral organs |
Beta-3 adrenergic receptor | Located in adipose tissue,vascular endothelium |
Alpha-2 adrenergic receptor | Located in presynaptic nerve terminals |
Alpha-1 adrenergic receptor | Located in post synaptic of effector cells |