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Vet Pharmocology
Lesson 2
Term | Definition |
---|---|
Five Rights of Drug Administration | -Right Patient -Right Drug -Right Dose -Right Route -Right time and Frequency |
Oral | By Mouth |
Emulsions | Milky solutions containing the drug |
Elixirs | Compound medicine held in solution by alcohol |
Topical | Placed on skin |
Liniments | Liquid rubs thinner than ointment. |
Administering Medications can be done with: | -Pill Guns -Speculum (tool placed in cavity opening) -stomach tube -Sryinge -or with your hands |
Four types of syringes | -Slip tip -Luer Lock -Eccentric tip -Catheter tip |
Slip Tip Syringe | most commonly used. |
Luer Lock Syringe | screw top that secures the needle to the syringe. |
Eccentric Tip Syringe | used when injecting larger volumes (greater than 20 mls) into a vein. |
Offset Hub Syringe | syringe allows you to place a large syringe parallel to the vein you're trying to inject. |
Catheter Tip Syringe | good for oral feeding catheters. |
Endotracheal Tubes | placed in the trachea. |
Medications concentrations come in many different unit sizes: | Metric: Grams, liters Apothecary System: grains, ounces Household System: ggt(drops), teaspoons, tablespoons |
Conversion Factor | 1 kilogram = 2.2 pounds To convert pounds to kilograms, divide the pounds by 2.2 to get the weight in kilograms. To convert kilograms to pounds, multiply the weight in kilograms by 2.2 to get the weight in pounds. |
Central Nervous System | brain, and spinal cord. |
Peripheral Nervous System | nerves |
Neuron | basic unit of the nervous system |
Dendrites | carries electrical impulses carried by the fibers INTO the neuron |
Axon | carries electrical impulses carried by fibers AWAY from the neuron |
Neurotransmitters | chemicals released bind to receptors on dendrite |
-mimetics | Drugs that imitate neurotransmitters |
-lytics | Drugs that disrupt neurotransmitters |
Lyse | Disrupt |
Somatic Nervous System | nerves connecting the central nervous system to brain and to the skeletal muscles |
Autonomic Nervous System | composed of sympathetic and parasympathetic nervous systems. associated with 'fight or flight' (adreneric) dopamine, epinephrine (adrendaline), norepinephrine. |
Parasympathetic Nervous System | Involves energy conserving processes. (Cholinergic)acethylcholine |
Autonomic Nervous System | -Imitating neurotransmitters -interfering with neurotransmitter release -Blocking the attachment of neurotransmitter release |
Cholinergic Agents | -Help diagnose myasthenia gravis -Reduce eye pressures with glaucoma -Stimulate gastrointestinal motility -Treat urinary retention -Control vomiting -Act as antidote for agents that prevent neuromuscular functioning |
Direct-acting Agents | attach to acetylcholine receptor |
Indirect-acting agents | inhibit the breakdown or removal of natural acetylcholine from the acetycholine receptors |
Bradycardia | Abnormally slow heartbeat |
Cholinergic Blocking Agents | block the action of acetylcholine at the muscarinic receptors. They: -Decrease gastrointestinal motility -Dilate pupils for eye examinations -Relieve ciliary spasms in the eye -treat sinus bradycardia |
Atropine/Glycopyrrolate/Aminopentamide Adverse Reactions | -Drowsiness -Disorientation -Tachycardia -Photophobia -Constipation -Anxiety -Burning sensation at site of injection |
Adrenergic Agents | catecholamine or noncatecholamine mediated. -Stimulate the heart to beat during cardiac arrest -Reverse hypotension and bronchoconstriction due to anaphylactic shock -Strengthen the heart during congestive heart failure |
Adrenergic Agents (Cont) | -Correct hypotension through vasoconstriction -Reduce capillary bleeding through vasoconstriction -Treat urinary incontinence -Reduce mucous membrane congestion found in allergic conditions |
Adrenergic Agents (Cont 2) | -Prolong effects of local anesthetic agents by causing vasoconstriction -Treat glaucoma |
Epinephrine stimulates all 4 receptors causing: | -Increased heart rate and cardiac output -constriction of skin blood vessels -dilation of muscle blood vessels -dilation of bronchioles -increase metabolic rate |
Vasopressor | Raises blood pressure |
analgesic | Pain relieving |
sedative | sleep causing |
Side effects of Norepinephrine | -Tachycardia -Hypertension -Nervousness -Cardiac arrhythmias |
Adrenic blocking agents | Interfer with the activity of the sympathetic nervous system |