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WVSOM - FA Oxidation
WVSOM -- Beta Oxidation and other FA oxidations
Question | Answer |
---|---|
Oleate | 18C DB 9 |
Linoleate | 18C DB 9,12 |
Linolenate | 18C DB 9,12,15 |
Arachinoale | 20C DB 5,8,11,14 |
Which cells never use B Oxidation | RBCs and Brain Cells |
Where does B oxidation occur | Mitochondria |
B oxidation utilizes which kind of metabolism | aerobic |
Uncommon Fatty Acids | Long chains with odd numbers of carbons |
Common Fatty Acids | Long Chain (even numbers) and mono- or polyunsaturated FA |
Medium Fatty Acid chains | 6-12 C |
Short Fatty Acid Chains | 4 carbons |
Very Long Acid Chains | more than 20 carbons |
Triacylglycerol Lipolysis | Tracylglycerol -> Diacylglycerol -> Monoacylglycerol -> Glycerol |
Long chain fatty acid cross the plasma membrane via | facilitated transport and diffusion |
Fatty acids transported on what protein in plasma | albumin |
How is ATP expended in the cytosol during B Oxidation | Fatty acids bound to acyl CoA molecules |
Carnitine | transports Fatty Acyl into mitochondria |
What binds to FA as soon as it enters the mitochondria | binds to another CoA |
When does B Oxidation occur | in a fast |
What mitochondria do not perform B oxidation | mitochondria in brain cells |
major regulation of B oxidation | Adipose (hormone sensitive) Lipase |
B oxidation Starting materials | Long Chain FA NAD+ FAD |
B oxidation products | Acetyl CoA NADH FADH2 |
How far are fatty acids cleaved during B oxidation | until there are only Acetyl CoA Molecules |
How many FADH2 and NADH produced in B oxidation | 1 per each B oxidation |
Propionyl- CoA | 3 carbons |
When is propionyl CoA Produced | when Fatty acid chains have odd numbers |
Where does Propionyl CoA enter the Kreb Cycle | production of Succinyl CoA |
FADH2 production from B oxidation of unsaturated fatty acids | 1 less FADH2 per double bond |
When are medium chain fatty acids B-oxidized | as soon as they are absorbed from the gut |
w-oxidation produces | dicarboxylic acids |
Where does w-oxidation occur | opposite end of fatty acid chain that B oxidation occurs |
Peroxisomal Oxidation | oxidizes long, branched chains into fatty acyl-CoA that is then B oxidized |
Peroxisomal and W-fatty acid oxidation regulation | only by the supply of fatty acids they oxidize |