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pharmacology
Stack 10211973
Question | Answer |
---|---|
study or science of drugs | pharmacology |
studies the absorption, distribution, metabolism and excretion of drugs | pharmocokinetics |
enteral | mouth, NG, or rectal |
parenteral | skin |
percutaneous | topical, inhalation |
solubility of a drug | absorption |
how fast drugs can get to an area through the blood stream | distribution |
biotransformation-the liver is chemically inactive | metabolism |
elimination | excretion |
is the length of time it takes to remove 50% of the drug being administered | half life |
more severe reactions to drugs | adverse effects |
damage to kidneys | nephrotoxicity |
damage to the kidneys | hepatotoxicity |
unique, not normal responses | idiosyncratic |
unexpected reaction, reaction to drugs caused by antibodies | hypersensitivity; ex. penicillin |
severe allergic reaction | anaphylaxis |
Signs of hypersensitivity | hives, rash, itching and swelling |
What happens when a person has a anaphylaxis reaction | heart stops, trouble breathing, and maybe be fatal |
When one drug changes the action of another drug; | drug interactions |
Where does metabolism take place | liver |
when 2 drugs combined have the same effect as 1 active ingredient | additive effect |
When one drug interferes with action of another drug | antagonistic |
When one drug Q pushes drug B out of place at the receptor site - then drug A takes over giving only the effect from that drug. | displacement |
when 2 drugs don't work together chemistry reaction - bad | incompatibility |
when 1 drug promotes rapid excretion of another drug; therefor; increasing the effect | interference |
effect of 2 drugs given at the smae time is greater than the effects of each drug given alone | synergistic effect |
what is the route for topical ointment | percutaneous |
where do you place a sublingual tablet | under the tongue |
directly into dermis or subcutaneous or muscular, IV, IM | parenteral |
Example of a sublingual tablet | nitrogylcerin |
Where do you place a tablet that is buccal | against mucous membrane - cheek |