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Chapter 15-18
Question | Answer |
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Which of the following statements regarding viruses is false? | A virus is generally considered to be alive because it is cellular and can reproduce on its own. |
Which of the following people conducted the experiments that demonstrated that DNA is the genetic material of bacteriophages? | Hershey and Chase |
One type of virus that infects bacteria is called a | phage |
When a T2 bacteriophage infects an Escherichia Coli cell, which part of the phage enters the bacterial cytoplasm? | only the DNA |
The way that genetic material of a bacteriophage enters a bacterium is most like the way that | a dru is injected with a hypodermic needle. |
The monomers of DNA and RNA are | nucleotides |
Which of the following statements regarding DNA is false? | DNA uses the nitrogenous base uracil |
Which of the following statements regarding RNA is false? | RNA uses the sugar dextrose |
The shape of a DNA molecule is most like | a twisted rope ladder |
Which of the following statements regarding a DNA double helix is always true? | The amount of adenine is equal to the amount of thymine, and the amount of guanine is equal to the amount of cytosine |
DNA replication | uses each strand of a DNA molecule as a template for the creation of a new strand |
If one strand of SNA is CGGTAC, the corresponding strand would be | GCCATG |
When one DNA molecule is copied to make two DNA molecules, the new DNA contains | 50% of the parent DNA |
Which of the following enzymes catalyzes the elongation of a new DNA strand? | DNA polymerase |
Why does a DNA strand grow only in the 5' to 3' direction? | Because DNA polymerases can only add nucleotides to the 3' end of the growing molecule |
Which of the following options best depicts the flow of information when a gene directs the synthesis of a cellular component? | DNA--RNA--protein |
The transfer of genetic information from DNA to RNA is called? | transcription |
The "one gene-one polypeptide" theory states that | the function of an individual gene is to dictate the production of a specific polypeptide |
Experiments have demonstrated that the "words" of the genetic code (the units that specify amino acids) are | three-nucleotide sequences |
The directions for each amino acid in a polypeptide are indicated by a codon that consists of _________ nucleotide(s) in an RNA molecule. | 3 |
We would expect that a 15-nucleotide sequence will direct the production of a polypeptide that consists of | 5 amino acids |
A base substitution mutation in a gene does not always result in a different protein. Which of the following factors could account for this? | The fact that some amino acids are specified from more than one codon |
Which of the following enzymes catalyzes the linking together of RNA nucleotides to form RNA? | RNA polymerase |
Which of the following occurs when RNA polymerase attaches to the promoter DNA? | initiation of a new RNA molecule |
___________ marks the end of a gene and causes transcription to stop. | A terminator |
Where do transcription and translation occur in prokaryotic cells? | in the cytoplasm |
Which of the following statements about eukaryotic RNA is true? | Exons are spliced together |
Which of the following takes place during translation? | the conversion of genetic information from the language of nucleic acids to the language of proteins |
Which of the following options most accurately lists the sequence of events in translation? | codon recognition--peptide bond formation--translocation--termination |
Which of the following statements regarding the flow of genetic information is false? | Transcription occurs in the cytoplasm of eukaryotic cells. |
Any change in the nucleotide sequence of DNA is called? | a mutation |
Consider the following sentence: "The dog did not eat." Which of the following variations of this sentence is most like a base substitution mutation? | The doe did not eat |
Consider the following sentence: "The dog did not eat." Which of the following variations of this sentence is most like a reading frame mutation? | The dod idn ote at. |
A physical or chemical agent that changes the nucleotide sequence of DNA is called a(n) | mutagen |
Which of the following features characterizes the lytic cycle of a viral infection? | The cycle typically leads to the lysis of the host cell. |
Which of the following statements is false? | The lysogenic cycle typically results in the rapid lysis of all infected cells. |
Viral DNA incorporated into host cell DNA is known as a(n) | prophage |
Which of the following statements regarding viral diseases is false? | Very few new human disease have originated in other animals because the genetic differences are too great. |
What will be the most likely cause of a new avian flu pandemic like that 1918-1919 flu pandemic that killed approximately 40 million people worldwide? | easy viral transmission from person to person |
What kind of virus is HIV? | a retrovirus |
Which of the following enzymes does HIV use to synthesize DNA on an RNA template? | reverse tanscriptase |
HIV does the greatest damage to | white blood cells |
How do viroids harm the plants that are infected with them? | by altering the plants' growth |
Which of the following statements about the treatment of prevention for a prion infection is true? | There is no known treatment or cure for prion infections |
In the 1920's, Frederick Griffith conducted an experiment in which he mixed the dead cells of a bacterial strain that can cause pneumonia with live cells of a bacterial strain that cannot. When he cultured the live cells, some of the daughter colonies pro | transformation |
Transduction | occurs when a phage transfers bacterial DNA from one bacterium to another. |
Conjugation | is the direct transfer of DNA from one bacterium to another |
Conjugation, transformation, and transduction are all ways that bacteria | increase their genetic diversity |
When a bacterial cell with a chromosome-borne F factor conjugates with another bacterium, how is the transmitted donor DNA into the recipient's genome? | It is substituted for the equivalent portion of the recipient's chromosome by the process of crossing over |
In many bacteria, genes that confer resistance to antibiotics are carried on | R plasmids |
Conjugation between a bacterium that lacks an F factor (F-) and a bacterium that has an F factor on its chromosome (F+) would typically produce which of the following results? | The F- bacterium ends up with a recombinant chromosome that carries some genes from the F+ bacterium, and the F+ bacterium ends up with an unaltered chromosome. |
A functional F factor that is an R plasmid must contain all of the following elements except | a site for making the proteins needed for conjugation. |
Which of the following human activities has contributed to an increase in the number of bacteria having R plasmids? | heavy use of antibiotics in medicine and in agriculture |
Which of the following statements about the problems created by cloning is false? | Cloned animals live longer compared to naturally bred animals |
The fact that the nucleus from an adult somatic cell can be used to create all of the cell types in a new organism demonstrates that development depends upon | the control of gene expression |
The term "gene expression" refers to the | process by which genetic information flows from genes to proteins |
A gene operon consists of | transcribed genes, an operator, and a promoter |
In a prokaryote, a group of genes with related functions along with their addicted control sequences, defines | an operon |
The lac operon in E. Coli | prevents lactose-utilizing enzymes from being expressed when lactose is absent from the environment |
Proteins that bind to DNA and turn on operons by making it easier for RNA polymerase to bind to a promoter are called | activators |
The lac operon of E. Coli is __________ when the repressor is bound to lactose. | active |
The expression of the tryptophan operon is controlled by | a repressor that is active when it binds to tryptophan |
Which of the following is likely to occur in E. Coli cells that are grown in skim milk? | The trip repressor is activated and the cells will produce lactose-utilizing enzymes |
A single cell, the zygote, can develop into an entirely new organism with many different specialized cells. Which of the following statements about this process is false? | Additional genetic information for the formation of specialized cells is passed on to the developing embryo via the placenta |
The genes for the enzymes of glycolysis | are active in all metabolizing cells, but the genes for specialized proteins are expressed only in particular cell types. |
Which of the following statements regarding DNA packing is false? | DNA packing tends to promote gene expression |
The relationship between DNA and chromosomes is most like | thread wrapped around a spool |
In female mammals, the inactive C chromosome in each cell | becomes a Barr body |
The tortoiseshell pattern on a cat | results from X chromosome inactivation |
Both prokaryotic and eukaryotic cell use _______ to turn certain genes on or off. | regulatory proteins |
Enhancers are | the site on DNA to which activators bind |
Silencers are sites on DNA that | bind repressor proteins to inhibit the start pf transcription |
RNA splicing involves the | removal of introns from the molecule |
The coding regions of a gene (the portions that are expressed as polypeptide sequences) are called | exons |
Which of the following permits a single gene to code for more than one polypeptide? | alternative RNA splicing |
Small pieces of RNA that can regulate mRNA transcription are called | microRNA |
miRNA can be used by | cells to prevent infections from double-stranded RNA viruses |
Which of the following statements regarding RNA and proteins is false? | In eukaryotes, one gene controls the production of just one functioning protein. |
All of the following mechanisms are used to regulate protein production except | DNA editing |
The textbook authors' analogy between the regulation of gene expression and the movement of water through pipes includes all of the following except | the web of control that connects different genes |
Which of the following mechanisms of controlling gene expression occurs outside of the nucleus? | translation |
Which of the following statements about fruit fly development is false? | The location of the head and tail ends of the egg is primarily determined by the location of sperm entry during fertilization |
A homeotic gene | serves as a master control gene that functions during embryonic development by controlling the developmental fate of groups of cells |
Which of the following statements about microarrays is false? | Microarrays use tiny portions of double-stranded RNA fragments from a large number of genes. |
To initiate a signal transduction pathway, a signal binds to a receptor protein usually located in the | plasma membrane |
Transcription factors attach to | DNA |
A signal outside a cell triggers changes in the transcription and translation inside the cell through the process of | signal transduction pathways |
The basis of cellular differentiation is | selective gene expression |
Most differentiated cells retain | a complete set of their genes, and retain the ability to express those genes under certain circumstances |
The cloning of Dolly the Sheep | demonstrated that the nuclei from differentiated mammalian cells can retain their full genetic potential |
Which of the following mammals has not yet been cloned and brought through the complete gestation cycle? | human |
Which of the following possible uses of reproductive cloning is still considered by most to be an unresolved ethical issue? | the production of genetically identical humans for therapeutic purposes |
Adult stem cells have limited therapeutic potential | because their developmental potential is limited to certain tissues |
A gene that can cause cancer when present in a single copt in a cell is called a(n) | oncogene |
Which of the following statements about photo-oncogenes is false? | A mutation in a tumor-supressor gene can stop cell division immediately |
Which of the following is not a factor that contributes to norma cells becoming cancerous? | one or more of the cell's genes being removed by a virus |
Cancer of the colon is caused by | several somatic cell mutations |
The development of colon cancer occurs slowly and is more prominent in the elderly than the young. This is most likely because | four or more somatic mutations must occur to giver rise to the center, which takes time |
Mutations on the photo-oncogenes as and p53 | disrupt normal regulation of the cell cycle |
Mutations in the p53 gene can lead to cancer by | turning off a gene for a protein that inhabits cell division |
The carcinogen known to cause the most cases of cancer is | tobacco |
Which of the following statements regarding cancer risk factors is false? | Mutagens are usually not carcinogens |