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Fungal, Viral, Para
Drugs for Fungal, Viral, Parasitic Diseases (PT LPN Ch 11+12)
Identify Major Drug Groups that Treat Fungal Infectons | Fungicidal and Fungistatic |
Fungal Infections are either | Systemic or Superficial |
Fungicidal | Ability to destroy fungi |
Fungistatic | Able to slow multiplication of fungi |
Superficial Mycoses affect what parts of the body | Scalp, Skin, Nails and mucus membranes |
Systemic mycoses affect what parts of the body | Internal organs, lungs, brain, GI, etc |
Another name for a Fungal Infection | Mycoses |
Antibiotics are a always effective against Fungal Infections | False - most fungal infections are unaffected by antibiotics |
Examples of Systemic Antifungal Drugs | Fluconazole (Diflucan) Amphotericin B (Amphotec, Fungizone) Griseofulvin (Fulvicin) |
Adverse Effects of Systemic Antifungal Drugs | Headache, malaise, abdomen/joint/muscle pains, Anorexia - and Nephrotoxicity |
Systemic Fungal Infections - Nursing Interventions and Pt Teaching | use cautiously in renal dysfunction and hepatic impairment |
If given with Digoxin, Amphotericin B may increase | Digoxin Toxicity |
Fluconazole mare increase the effects of | Oral Hypoglycemics |
Griseofulvin (Fulvicin) can decrease the effects of | Warfarin AND Oral Contraceptives |
Superficial Fungal Infections are usually treated with | Topical forms of antifungals - OTC creams, gels, and ointments |
Candidasis | Affects the skin, nails, oral cavity (thrush), vagina. Superficial |
Tinea Pedis | Athlete's Foot |
Tinea Cruris | Jock itchy!! Yum. |
Tinea Capitus | Ringworm of the scalp |
Examples of Superficial Antifungal Medications | tolnaftate (Tinactin) miconazole (Lotrimin, Monistat) Nystatin (Mycostatin) |
Adverse Reactions of Superficial Antifungal Medications | skin irritation and redness burning and itching |
Superficial Antifungal Nursing Interventions and Teaching | Clean Area Involved Wear gloves Do not apply to open wounds Do not share clothing and towels |
Nystatin administration | swish and swallow, no food or drink 30 minutes after |
The patient has oral candidiasis. Which of the following meds does the nurse expect to be ordered? A. Lamisil B. Mycelex C. Nizoral D. Nystatin | D. Nystatin |
What is a Virus? | Non living particle that infects bacteria, plants and animals |
Viruses require what to replicate? | A host |
Many viruses are self limiting and do not require | Treatment |
5 siblings of the Herpes Virus Family | HSV- Type 1 HSV - Type 2 CMV (Cytomegalovirus) Vericella - Zoster Epstein-Barr |
HSV Type 1 causes infections of | the eye, mouth, and lips. Commonly called a cold sore. |
HSV Type 2 causes infections of | the genitalia |
CMV or Cytomegalovirus affects what body systems | multiple body systems - usually in immunosuppressed patients |
Varicella/Zoster Virus cause what and what | Zoster causes Shingles Varicella causes Chickenpox |
Epstein-Barr virus causes | Mononucleosis (Mono) |
Antiviral Medications work by interfering with... | A virus's ability to reproduce in a cell |
True or False: Antivirals can cure a patient | False: They do not cure a patient, most often the virus simply lays dormant. |
Antiviral Adverse Effects | N/V/D H/A Rash |
Antivirals for Herpes Infections (common) | - Valtrex (valacyclovir) - Abreva (docosanol |
most common antiviral for Influenza | Tamiflu (oseltamivir) |
When to begin Antiviral therapy | As soon as symptoms appear |
When to use Antiviral in pregnancy and lactation | only when the benefit outweighs the risk |
Antivirals do not stop the spread of disease to | other people. So, wash your hands and stuff... |
When lesions are present you should | avoid physical contact. wear gloves and things |
Protozoans | Single-celled Organism |
Mites, Ticks, Worms (Helminths) | Multicellular animals |
Antiprotozoal Drugs aid in what infections | Protozoan |
Antihelmintic Drugs aid in what infections | Multicellular animals... worms (Helminths) , mites, ticks, |
Examples of (2) Protozoan Infections | Malaria and Amebiasis |
Malaria is caused by | bite from an infected mosquito |
Amebiasis is | severe form of diarrhea! (dysentery) |
Common Drugs (2) prescribed for Protozoan Infections | Flagyl (metronidiazole) Plaquenil (hydroxychloroquine) |
Adverse Reactions of Antiprotozoal Drugs | N/V/D, Abdomen Cramping, Anorexia Visual Disturbances, Dizziness |
Flagyl can cause what specific AE | Peripheral Neuropathy |
Helminths | Parasitic worms (hookworms, pinworms, roundworms, tapeworms, flukes) |
Where do Helminths love to attach themselves | GI Tract mucosa |
Helminths are often found in areas with | poor sanitation |
Common examples of Antihelmintic Drugs (2) | - Antiminth, pinX (pyrantel - Albenza (albendazole) |
Antihelmintic AE's | N/V/D, Headache, dizziness |
Antihelmintic Nursing Interventions | OMG, wash your hands a lot. Take showers NOT baths. |
During Helminth Infection how often should laundry be changed | Daily changes of towels, linens and underwear. |