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protazoal pharm
Question | Answer |
---|---|
chloroquine | raises PH of vacuoles |
chloroquine | effective against erythrocytic forms |
chloroquine | not for prophylactic or radically currative use |
chloroquine side effects | GI upset, prutitus, mild CNS disturbances |
Primaquine | effective against exoerythrocytic stage |
Primaquine | not for casual prophylactic use, is currative when combined with blood schizontricide |
Primaquine | may promote hemolysis |
Quinine | active against erythrocytic stage |
quinine | restiance is uncommon |
quinine | causes headache, nausea, visual disturbances, dizziness, tinnitus, Gi irritant, produce CNS disturbance, renal damage, and hemolytic anemia |
mefloquine | used for prophylaxis and treatment of resistant P. falciparum |
mefloquine side effects | dizzy, GI and visual disturbances |
Dihydrofolate reductase inhibitors | Pyrimethamine and chloroguanide |
Antibacterial agents used for malaria | sulfonamides and tetracyclines |
metronidazole | Flagyl |
metronidazole | inhibits DNA sythesis, tissue amebicide, side effects: GI, mild reversible CNS disturbances |
Iodoquinol | active against ameaba trophozoites and cysts in lumen |
lodoquinol | toxic doses-optic atrophy |
other amebicides | paromomycin, diloxanide furate, emetine, chloroquine |
leishmaniasis | stibgluconate sodium, pentamidine, amphotericin B, Allopurinol |
trypanosomiasis | nifurtimo, suramin, eflornithine hydrochloride, melarsoprol, pentamidine |
Giardiasis | QUINACRINE, metronidazole, furazolidone |