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cephalosporin Gens

Quick cephalosporin classification quiz

QuestionAnswer
What generation Cephalosporin is Cefepime? 4th Generation
What generation Cephalosporin is Cefazolin? 1st generation
What generation Cephalosporin is Cefotaxime? 3rd generation
What generation is Cephalosporin Cefuroxime? 2nd generation
What generation is Cephalosporin Cefotetan? 2nd generation
What generation Cephalosporin is Ceftriaxone? 3rd generation
What generation Cephalosporin is Cephalexin? 1st Generation
What generation Cephalosporin is Cefoxitin? 2nd Generation
What generation Cephalosporin is Ceftazidime? 3rd Generation
What generation Cephalosporin is Cefoperazone? 3rd Generation
What organisms are not covered by cephalosporin tx Listeria, Atypical bacteria, MRSA, enterococci (mnemonic = LAME)
DOC for surgical prophylaxis? Cefazolin
What bacteria are indicated for tx with 1st generation cephalosporins? Highly active against gram +, weak againt gram - except for Proteus mirabilis, E. coli, Klebsiella. (PEcK)
Indications for 2nd generations cephalosporins? Same as 1st generation plus hemophilus inluenzae and N. meningitidus. MIXED ANAEROBIC INFXON SUCH AS PERITONITIS
What Cephalosporin is RX for peritonitus? Cefoxitin and Cefotetan
Indications for 3rd generation cephalosporins? Wide variety of serious infxons caused by organisms resistant to other drugs. Ceftazidime for pseudomonas and ceftriaxone for gonorrhea. Crosses BBB And resistant to most Beta lactimases
Spectrum / indications for 4th generation cephalosporines? Combines G(+) activity of first generation with wider G(-) spectrum of 3rd generation. Increased resistance to beta-lactimases
Cephalosporine of choice for pseudomonal infxon? Ceftazadime or Cefepime
Cephalosporine of choice for Gonorrhea? Ceftriaxone (IM) or Cefixime
Cephalosporine of choice for bacterial meningitis (pneumococci, meningococci, H influenzae and susceptible G(-) rods? Ceftriaxone or Cefotaxime
Cephalosporine of choice for typhoid fever? Ceftriaxone
Cephalosporine of choice for acute otitis media? Ceftriaxone
Cephalosporine of choice for Anaerobic infxons (GI, PID, etc)? Cefoxitin, Cefotetan (against B. fragilis)
What cephalosporins cause a disulfiram-like rxn? Cfoperazone, cefamandole, and cefotetan... inhibits aldehyde dehydrogenase due to MTT ring.
What cephalosporin causes neutropenia? Ceftazidime
Created by: rkirchoff
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