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NT_Review
Quick neurotransmitter review (use in MCQ or matching mode)
Question | Answer |
---|---|
Cortical activation | Ach |
cognitive function | Ach |
memory processing | Ach |
REM sleep | Ach |
Motor coordination | Ach |
Motor planning and execution | DA |
Reward processes | DA |
Inhibition of prolactin secretion | DA |
Emesis | DA |
Arousal and sensory processing | NE |
Pain control | NE, opioid peptides, serotonin |
Sleep-Wake Cycle | NE |
Attention | NE |
Stress response | NE |
Temperature regulation | Histamine |
Vascular dynamics | Histamine |
Motor coordination and neuronal excitability in the brain | GABA |
Long-term memory | Glutamate |
Pain processing | Glutamate |
Neuronal toxicity and apoptosis | Glutamate |
Motor coordination and neuronal excitability in the spinal cord | Glycine |
Stress response, vision, hearing and taste. | Opioid peptides. |
Alzheimer's dz | Ach |
Schizophrenia | DA |
Parkinson | DA |
Drug dependence | DA |
Hallucinations | DA and 5-HT and Glutamate |
Depression | NE and 5-HT |
Stress related disorders | Opioid peptides and NE |
OCD | 5-HT |
Anxiety disorders | GABA and 5-HT |
Fever | Histamine |
Epilepsy | GABA and Glutamate |
Convulsive Seizures | Glysine |
GABA-A receptors activation result in <increase/decrease> in ___ion____ while GABA-B receptor activation results in <increase / decrease> in ___ion____ | GABA-A activation (Ionotropic)---> open Cl- channels ---> IPSP while GABA-B activation (metabotropic) ---> Open k+ channels ---> K+ efflux results in IPSP. |
Anxiolytic drugs are most commonly of what family of drugs> | benzodiazepines. --> INCREASE GABA ACTIVITY |
OCD is most commonly associated with dysfunction of what NT acvitivity | serotonin |
Give two examples of heteroreceptors in the CNS | GABAa receptors on nerve terminals of cortical pyramidal neurons and Glumate receptors on nerve terminals in the mesolimbic pathway. (From Babbini et. al.) |
In general, what are the 3 NTs involved in decreasing pain signalling / inducing analgesia? | Serotonin, NE, opioid peptides |