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Electrophysiology
Neuropathology
Question | Answer |
---|---|
What is NCS/EMG used for? | To reveal lower motor neuron phenomenon |
Injury or disease of the nerve is called? | neuropathy |
Injury and or disease of the muscle is called? | myopathy |
What are three types of myopathy? | genetically determined, toxic, and inflammatory |
Can peripheral nerves regenerate? | yes |
If these are destroyed peripheral nerves cant regenerate. | perikaryons |
The perikaryon is also known as the what? | cell body |
The axon grows at a rate of ______. | 1-3mm/day |
Nerve fiber distal to the injury degenerates along with its myelin sheath = ? | wallerian degeneration |
After nerve injury what does the nucleus do? | moves to the periphery |
After nerve injury what happens to the nissl bodies? | they become greatly reduced |
Three weeks post nerve injury muscle fibers show pronounced atrophy secondary to ________. | denervation |
About how long does it take for the nerve fiber to regenerate? | 3 months |
neurapraxia, axonotmesis, neurotmesis, all are considered axonal degeneration neuropathies...which form of nerve classification does this describe? | seddon |
five degrees, based on pathology and EMG/NCS changes...which form of nerve classification does this describe? | Sunderland |
Conduction loss (temporary or transient block) without structural loss of the axon – mildest form of nerve block is what? | neurapraxia 1st degree |
What are common causes of neurapraxia 1st degree? | compresison, ischemia, ionic changes of the nerve fibers |
With neurapraxia, recovery takes place within _______ following removal of the cause. | days or weeks |
Axons lose continuity with subsequent wallerian degeneration along the distal segment followed by denervation-induced muscle atrophy is called? | axonotmesis |
With axonotmesis conduction ceases ________ across the site of the nerve injury. | imeediatly |
With axonotmesis there is _________ loss of excitability first at the neuromuscular junction then the distal nerve segment. | irreversible |
Axonotmesis recovery depends on what and can take how long. | regeneration of nerve fibers, can take months to years |
an injury that separates the entire nerve, including the supporting connective tissue is called? | neurotmesis |
If pt's with nerotmesis do not have _______ _______, regeneration proceeds slowly, resulting in an incomplete and poorly organized repair. | surgical intervention |
In neurotmesis, what kind of response do you get with a NCS? | No response with stimulation proximal or distal to the lesion (motor or sensory) |
Degeneration of muscle fibers and infiltration by CT resulting in progressive muscle weakness is? | myotonia |
myotonic discharges (trains of PWs) provoked by voluntary contraction or moving the needle - wax and wane (“divebomber”) NCS normal...what does this describe? | myotonia |