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Blood 411
Blood drugs
Question | Answer |
---|---|
Heparin Onset of Action | Immediate |
Anticoagulant DOC for pregnant women | Heparin |
LMWHs drugs | Ardeparin, Dalteparin, Enoxaparin |
LMWHs Route, Tests, ADRs | Subcutaneous, no tests, less bleeding |
Glycoprotein IIb/IIIa Inhibitors drugs | Abciximab, Eptifibatide, Tirofiban |
Anticoagulants | Heparin, Warfarin |
Antiplatelet agents | Glycoprotein IIb/IIIa Inhibitors, Thienopyridines |
Thrombolytics drugs | Alteplase, Anistreplase, Reteplase, Streptokinase, Urokinase |
Glycoprotein IIb/IIIa Inhibitors MOA | Inhibit platelet aggregation by preventing binding of adhesion ligands to GP IIb/IIIa receptor on platelet |
Thienopyridines drugs | Clopidogrel, Ticlopidine |
Thienopyridines MOA | Inhibits platelet aggregation by binding to platelet ADP receptor |
Thrombolytics Contraindications | Aneurysm, active bleeding, brain tumor, stroke, CNS surgery last 2 mos, severe HTN, trauma |
Eptifibatide | Glycoprotein IIb/IIIa Inhibitors drugs |
Tirofiban | Glycoprotein IIb/IIIa Inhibitors drugs |
Ticlopidine | Thienopyridines drugs |
Clopidogrel | Thienopyridines drugs |
Abciximab | Glycoprotein IIb/IIIa Inhibitors drugs |
Ardeparin | LMWHs drugs |
Enoxaparin | LMWHs drugs |
Dalteparin | LMWHs drugs |
Alteplase | Thrombolytics drugs |
Anistreplase | Thrombolytics drugs |
Reteplase | Thrombolytics drugs |
Streptokinase | Thrombolytics drugs |
Urokinase | Thrombolytics drugs |
Leukopenia | decreased WBCs |
Leukocytosis | increased WBCs |
Thrombocytopenia | decreased platelet conc. |
Thrombocytosis | increased platelet conc. |
Primary protein component. For osmotic pressure gradient | Albumin |
Blood proteins that help protect body against infections | Globulins |
Blood proteins that help with coagulation | Fibrinogen |
Warfarin onset | Slow |
Heparin Route | IV |
Warfarin Route | PO |
Heparin Duration | Short |
Warfarin Duration | Long |
Heparin Tests | aPTT |
Warfarin Tests | PT, INR |
Heparin Antidote | Protamine SO4 |
Warfarin Antidote | Vitamin K |