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physiology
exam 6
Question | Answer |
---|---|
preload | how full is cardiovascular system w/blood. affected via dehydration and trauma. amount of blood in heart before it contracts. |
afterload | how hard it is for heart to eject blood. once filled it is easy or hard to contract. resistance to ejection |
contactality | force/tension. force and velocity |
elastance | stiffness of something you stretch. relationship b/w volume and pressure |
what did William Harvey discover | blood moved around a circuit |
vascular capacitance | volume/pressure |
relationship between area and velocity | as area increases velocity decreases with constant flow |
cardiac output | (mean arterial pressure- right atrial pressure)/ total peripheral resistance |
pressure relationship in arteries and veins | low in vein, high in arteries. Therefore blood flows from arteries to veins. |
ejection fraction amount | 50-60% |
resistance in series | increases b/c additive effect |
resistance in parallel | decreases |
when does a murmur occur | when flow is too high and creates turbulance. loudness does not determine severity. |
why do capillaries have the largest SA but low blood volume | they are so small. small proportion overall exchange takes place in them. |
stressed volume | the amount of blood that determines vascular filling pressure. 20-25% of the total blood volume |
unstressed volume | large reservoir of available blood that can be recruited to maintain vascular filling pressure |
alpha 1 and alpha 2 receptors | activate smooth muscle. cause vasoconstriction. transfer blood volume to arterioles from veins. blood must have gone through lungs. 8-15ml/kg transfusion rate. |
normal mean pressure mm Hg in aorta | 80-100. |
what happens if mean pressure mm HG in aorta is less than 60 | potential for some organs to not be adequately profused. gut and kidney deprived first. |
is pressure lower in right or left atrium | right atrium |
pulse pressure | difference between systolic and diastolic pressure. |
phase 4 | resting membrane potential via Na/K ATPase pump |
phase 1 | when hit threshold potential, change mem enough, Na enter rapidly via voltage gated channels. cell more and more pos. when too pos, cl and k channel open. move neg. |
phase 2 | plateau phase. still pos, Ca enters cell with Na via L type Ca channel. |
phase 3 | more neg with K leaving cell. repolarization. |
examples of latent pacemakers in heart | 1. AV node 2. Bundle of His 3. Purkinje fibers |