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Glycolysis
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Conversion of pyruvate into acetyl CoA consists of three steps
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chapter biochem

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QuestionAnswer
Glycolysis Produces pyruvate
Conversion of pyruvate into acetyl CoA consists of three steps Decarboxylation, oxidation, and acetyl transfer
Pyruvate dehydrogenase A regulatory kinase and phosphatase are part of the mammaian PDH E2 contains three domains Several copies each E1 and E3 surround E2 The complex contains multiple copies of each of three enzymes
Coenzyme prosthetics FAD, TPP/TDP. Lipoamide
What is benefit of substrate channeling Intermediates of a multistep reaction sequences do not dissociate from the enzyme complex
Select the factors that stimulate the pyruvate dehydrogenase complex Dephosphrylation of E1 Increase in Ca 2+ concentration
What is the fate of pyruvate if a person has PDH deficiency It is processed to lactate
Identify how DCA acts to stimulate pyruvate dehydrogenase activity DCA inhibits pyruvate dehydrogenase kinase
Identify the status of the pyruvate dehydrogenase complex in patients who responds to DCA Pyruvate dehydrogenase complex displays some residual activity
What is the biochemical explanation for the symptoms of neurological dysfunction displayed by mercury nitrate The dihydrolipoamide group of pyruvate dehydrogenase complex is inactivated , preventing the gluclose in the brain
Which additional process will be inhibited in the dorsal root ganglion under conditions the citric acid cycle
True statements about citric acid cycle ` acetyl-CoA is graded to produce NADH and FADH2 Aerobic process NADH, GTP, FADH2, and Coenzyme A
Citric acid cycle 2CO2 4 reduced coenzymes 1 ATP
Which enzymes produce NADH as a product Isocitrate dehydrogenase Malate dehydrogenase A-ketoglutarate dehydrogenase
Which of the compounds in the citric acid cycle are high energy compounds or transfer chemical energy GTP FADH2 NADH
Which enzymes or enzyme complex is similar to the pyruvate dehydrogenase complex a-ketoglutarate Dehydrogenase
What are the key control points within the citric acid cycle a-ketoglutarate dehydrogenase
How should the nutritionist explain why fats cannot be directly converted into carbohydrates During glucongenesis, glucose is created from oxaloacetate. However, oxaloacetate general citric acid cycle. Because carbons from fats must enter the citric acid cycle CoA first become carbohydrates
Which enzymes of citric acid cycles yields a compound with high phosphorylated succinyl CoA syntethase
The citric acid cycle occurs mitchondrial matrix
Prokaryotic past Contain their own circular DNA Have a double membrane Replicate by a process similar to prokaryotes
ETC events Two electrons pass between cytochromes through a series of redox reactions NADH releases two hydrogens ions and donates two electrons to coenzyme Q
Donate electrons of ETC NADH FADH2
final ETC O2
Final products of ETC and oxidative phosphorylation NAD+ FAD H2O ATP
How do cytochromes donate and accept electrons each cytochrome has an iron-containing heme group that accepts electrons and then donates electronegative substance
What is the advantage of having complexes 1, 3, 4 associated with one another in It enables the rapid transfer of electrons, thereby increasing the efficiency of proton pumping
Electron transport chain complex inner mitchondrial complex 2
How many protons does complex 1 pump into the inter membrane space 4
Cytochrome c in the electron transport chain it transport an electron from complex 3 and complex 4
final electron acceptor cytochrome c oxidase
proton gradient in cellular respiration a higher concentration of (H+) on one side a membrane than the other
Proton gradient in the mitochondrion It is potential energy that can power ATP synthesis
ATP synthase ATP synthase would remain sensitive to Fo proton conduction translocation and ATP synthesis
How is oxaloacetate modified to a form that can be transported out of the matrix transamination
What direction is ATP 4+ transported during the active oxidative phosphorylation out of mitochondrial matrix
What drives the transport of adenine nucleotides The electrochemical gradient
What is the major regulator of oxygen consumption during oxidative phosphorlyation ADP
molecule controls the rate of the pentose phosphate pathway NADP+/NADPH
Epinephrine stimulates lipolysis in adipose tissue Glucoenogensis in liver glycogen breakdown glycolysis in muscle
What is fate of the radioactive label 14C appears C-5 of ribulose 5-phosphate
Which reaction requires the ATP Fructose 6-phophate ---> fructose 1,6 biphosphate
Red blood cells accomplish by producing lactate energy production in the form of ATP
how can red blood cells generate CO2 if they lack mitchondria the pentose phosphate pathway coupled with glucoeogensis
pentose phosphate pathway nucleotide synthesis biosynthesis reactions glucose 6-phosphate
controls rate of the pentose phosphate pathway NADP"/NADPH
Which reaction by the molecule in the first question glucose 6-phosphate dehydrogenase
Created by: Pearlhumphrey
 

 



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