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Retroviridae
Maedi/Visna Disease
Question | Answer |
---|---|
Who is this a disease of? | Adult sheep and sometimes goats |
What is visna? | Secondary encephalitic form of maedi |
What are 4 ways this virus can be transmitted? | Aerosolization. Ingestion of feces or urine. Colostrum and milk. Biting arthropods and surgical equipment. |
What is the main pathogenetic caracteristic observed in this disease? | Lifelong mononuclear cell-associated viremia |
When do most sheep seroconvert? What is the precentage of clinical disease? | 2-3 weeks AFTER infection. 5% |
Why is this disease seen in sheep 2 years or older? | There is a LONG incubation period ranging from months to 9 years! |
What are 2 other synonyms of Maedi? Iis this disease fatal? | Shortness of breath. Ovine Progressive Pneumonia (OPP). YES, within 3-8 months..especially with secondary bacT infections |
What does visna mean? What is interesting about this? | Wasting. Sheep maintain a good appetite if they are tended to. Those that are left to fend for themselves die of starvation. |
What two other clinical signs are seen with this disease? | Arthritis and Mastitis (noninflammatory fibrotic, reduction in milk production) |
What about immunity? | Viruses persist even though there are antibodies for it! |
What can be done to control and outbreak in an uninfected flock? | Pretesting and quarantine animals coming in. Retest animal every 6 months |