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L7 - Behavior Mods

Clin Pharm Ex 1

QuestionAnswer
Monoaminergic NTs Serotonin, NE, & DA
GABAergic NTs gamma-aminobutyric acid
Mild sedative & anxiolytic used to manage fear, phobia, & anxiety Benxodiazepines
Benzo can be used with... TCAs or SSRIs
When ending Benzo tx, be sure to... withdrawal slowly so don't precipitate seizures
Benzos should never be used in... aggressive patients
H2O insoluble Benzo that can induce hepatic toxicity Diazepam
Slow onset, longer acting Benzo that can also be used as an apetite stimulant in cats Oxazepam
Serotonin non-sedating anxiolytic used to manage fear, phobia, & anxiety Buspiron
Buspiron can be coupled with which drug to tx complex behavioral probs? Fluoxetine
Buspiron requires what to be clinically effective? several weeks of admin
Buspiron shouldn't be used in... patients w/severe hepatic or renal dz
Antidepressant drugs TCAs, SSRIs, & MAOIs
Amitriptyline is used to tx what in dogs? aggression, self-mutilation, & separation
Amitriptyline is used to tx what in cats? psychogenic alopecia, excessive vocalization, & idiopathic interstitial cystitis
TCAs in general cannot be used with... MAOIs
Most selective TCA Clomipramine
Clomipramine is used to tx what in dogs? separation anxiety, OCD, & dominance aggression
Clomipramine is used to tx what in cats? psychogenic alopecia & urine spraying
TCA that also has MAO activity Imipramine
Imipramine is used to tx... inappropriate urination, incontinency, & ejac dysfxn in horses
TCA that affects NE & 5-HT reuptake, potent H1 & H2 anti-histamine effects Doxepin
Doxepin is used to tx... psychogenic dermatitis related to anxiety
SSRI used to tx aggression & acral-lick dermatitis in dogs Fluoxetine
Fluoxetine is used to tx what in cats? spraying, psychogenic alopecia, & aggression
SSRI used to tx aggression & sterotypy in dogs Paroxetine
Sterotypy is best tx with... environmental changes
Paroxetine is used to tx what in cats? spraying & aggression
Amitriptyline SE include... sedation, mydriasis, urinary retention
Clomipramine SE include... sedation, regurg, anticholinergic signs
Imipamine SE include... weakness, ataxia (horses)
Doxepin SE include... antimuscarinic effects
Fluoxetine SE include... ↑ anxiety, irritability, altered sleep pattern
Paroxetine SE include... anorexia & constipation
Sertaline & Fluvoximine are SSRIs used to tx what in cats & dogs? aggression, OCD, & anxiety
Sertaline & Fluvoximine SE include... anorexia, constipation, behavioral & sleep pattern changes
SSRI that's also an a1 antag & weak 5-HT2a antag, Trazadone
Trazadone is used in dogs to tx... post surgery anxiety
Trazadone SE include... behavioral and sleep pattern changes
MAO-B oxidatively deaminates... DA, NE, Epi, & 5-HT
MAO-B inhib, NE & 5-HT reuptake inhib, & D2 receptor inhib Selegiline
Selegiline is best used in... cats
Selegiline is used to tx what in cats? aggression, ↓ appetite, compulsive licking, excessive vocalization, & cognitive dysfxn
Selegiline SE include... stereotypy in dogs (rare)
Created by: Dr_B.Phillips22
Popular Veterinary sets

 

 



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