click below
click below
Normal Size Small Size show me how
Drug Test #3
Green Block #3 - info quiz
Question | Answer |
---|---|
Diuretics help treat? | hypertension |
Diuretics increase elimination of? | water and electrolytes |
Increased urination | adverse reactions to diuretics |
Photosensitivity (Thiazide & Loop diuretics) | adverse reactions to diuretics |
Avoid prolonged exposure to sun (Thiazide & Loop diuretics) | auxiliary labels for diuretics |
May be advisable to eat bananas or drink orange juice (Thiazide & Loop diuretics) | auxiliary labels for diuretics |
Decrease vasoconstriction, peripheral resistance, blood pressure | Thiazide Diuretics |
Weak acids; Highly protein bound | Thiazide Diuretics |
Act in distal convoluted tubule | Thiazide Diuretics |
May rise serum glucose | Thiazide Diuretics |
Dehydration; Electrolyte deficiencies | adverse reactions to thiazide diuretics |
Excess uric acid & gout flare-ups | adverse reactions to thiazide diuretics |
Take in morning to avoid ... | nocturia |
Effect reduced when taken concurrently with ... | NSAIDs |
Tablets – 25mg, 50mg Common Doses: 12.5-50mg once daily (QAM) | Hydrodiuril |
Hydrodiuril | hydrochlorothiazide (HCTZ) |
Tablets – 1.25mg, 2.5mg Commonly dosed once daily (QAM) | Lozide |
Lozide | indapamide |
Tablets – 2.5mg Commonly dosed once daily, or a few days each week (mornings) | Zaroxolyn |
Zaroxolyn | metolazone |
Thiazide diuretics inhibit ___% sodium reabsorption | 5-10 |
Act in ascending loop of Henle | Loop diuretics |
Up to 98% protein bound | Loop diuretics |
Hypokalemia; Dehydration | adverse reaction to loop diuretics |
Severe hypotension | adverse reaction to loop diuretics |
Often taken with potassium supplement | Loop diurectics |
Loop dialectics inhibit ___% sodium reabsorption = Most potent diuretics | 20-30 |
Hydrodiuril; Zaroxolyn; Lozide | Thiazide diurectics |
Lasix (class) | Loop diurectic |
Lasix (generic name) | furosemide |
Tablets – 20mg, 40mg Commonly doses 1-2 times daily | Lasix |
Inhibit sodium reabsorption while sparing potassium loss | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
competitive antagonist of aldosterone | Aldactone |
Hyperkalemia (increased risk when taken with ACEIs); Gynecomastia; Hirsutism | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
Potassium Sparing Diuretics/Aldosterone Receptor Antagonists effectiveness increased when combined with ... | thiazide |
Potassium Sparing Diuretics/Aldosterone Receptor Antagonists inhibit ___% sodium reabsorption; Less effective than Thiazide & Loop diuretics | 1-3 |
Aldactone (class) | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
Aldactone (generic name) | spironolactone |
Tablets – 25mg, 100mg Common doses: 25-100mg once daily | Aldactone |
Take with Food Avoid salt substitutes and potassium rich diets | Aldactone |
Cardioglycosides are commonly used to treat? | Heart failure |
Increase cardiac output & force of myocardial contractions | Cardioglycosides |
Cardioglycosides have a narrow ___ (lethal dose close to therapeutic dose) | therapeutic index |
arrhythmias, dizziness, convulsions, delusions, coma | Digitalis toxicity |
Photophobia; visual disturbances; weakness; gynecomastia | adverse reaction to cardioglycosides |
Toloxin | Cardioglycosides |
Toloxin | digoxtin |
Tablets – 0.0625mg, 0.125mg, 0.25mg Commonly dosed once daily | Toloxin |
Antiarrhythmics are commonly used to treat | Arrhythmia (Irregular heart rates & rhythms) |
Other arrhythmias, bradycardia, dizziness, hypotension | adverse reaction to antiarrhythmics |
Class 1A, 1B, and 1C Antiarrhythmics | Sodium (Na) channel blocker |
quinidine sulfate; Procan SR | Class IA |
procainamide | Procan SR |
Xylocard | Class IB |
Lidocaine | Xylocard |
Tambacor; Rhythmol | Class IC |
propafenone | Rhythmol |
flecainide | Tambacor |
Class II | Beta (β) blocker |
Rhotral, Sectral; Inderal; Sotacor | Beta (β) blocker |
acebutalol | Rhotral, Sectral |
propranolol | Inderal |
sotalol | Sotacor |
Class III | Potassium (K) channel blocker |
Cordarone | Potassium (K) channel blocker |
amiodarone | Cordarone |
Class IV | Calcium (Ca) channel blocker |
Isoptin | Calcium (Ca) channel blocker |
verapamil | Isoptin |
Decrease in blood volume, peripheral resistance, and cardiac output leads to? | decreased blood pressure |