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MM- Immunity

TermDefinition
adaptive immunity immunity or resistance to a specific pathogen; slower to respond, has memory component
Apoptosis process of programmed cell death
Autoantigens antigens on the surface of normal body cells
B cells Cells manufactured in the bone marrow that create antibodies for isolating and destroying invading bacteria and viruses.
Cytotoxic T cells A type of T cell that kills infected body cells and cancer cells
endogenous antigens antigens produced by microbes that multiply inside the cells of the body
exogenous antigens include toxins and other components of microbial cell walls, membranes, flagella, and pili
Helper T cells T cells that help the immune system by increasing the activity of killer cells and stimulating the suppressor T cells
Interleukins proteins (cytokines) that are released from infected cells that stimulate the growth of B and T lymphocyte
Lymphocytes A type of white blood cell that make antibodies to fight off infections
Major Histocompatibility Complex (MHC) "flag" on top of cells; wait for a protein addition to signal if cell is healthy or infected.
memory cells General term for lymphocytes that are responsible for immunological memory and protective immunity.
MHC I When a healthy cell presents an antigen protein outside the cell to signal it is infected; signals cytotoxic T to destroy
MHC II Expressed on the surface of APCs (macrophages, dendritic cells, B cells) and functions by presenting antigen on the outside of the cell signaling that it is foreign in the body.
Regulatory T cells may function in preventing autoimmune reactions, also known as suppressor T cells
T cells Cells created in the thymus that produce substances that attack infected cells in the body.
self antigen An antigen placed on the MHC protein to signal that this is a healthy cell.
dendritic cells Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. They act as messengers between the innate and the adaptive immune systems.
Macrophages Found within the lymph nodes, they are phagocytes that destroy bacteria, cancer cells, and other foreign matter in the lymphatic stream by engulfing them using phagocytosis.
mast cells They serve as a first line of defense against antigens entering the body due to their location in the skin and mucosa
natural killer cells (NK cells) effector lymphocytes of the innate immune system that control several types of tumors and microbial infections by limiting their spread and subsequent tissue damage
Neutrophils Most common lymphocyte. A type of white blood cell that engulfs invading microbes and contributes to the nonspecific defenses of the body against disease. Cause pus formation.
Phagocytosis A type of endocytosis in which a cell engulfs large particles or whole cells
Endogenous Antigen foreign antigens that are present inside body cells
Exogenous Antigen include toxins and other secretions and components of microbial cell walls, membranes, flagella, and pili
Created by: srjones
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