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MM- Immunity
Term | Definition |
---|---|
adaptive immunity | immunity or resistance to a specific pathogen; slower to respond, has memory component |
Apoptosis | process of programmed cell death |
Autoantigens | antigens on the surface of normal body cells |
B cells | Cells manufactured in the bone marrow that create antibodies for isolating and destroying invading bacteria and viruses. |
Cytotoxic T cells | A type of T cell that kills infected body cells and cancer cells |
endogenous antigens | antigens produced by microbes that multiply inside the cells of the body |
exogenous antigens | include toxins and other components of microbial cell walls, membranes, flagella, and pili |
Helper T cells | T cells that help the immune system by increasing the activity of killer cells and stimulating the suppressor T cells |
Interleukins | proteins (cytokines) that are released from infected cells that stimulate the growth of B and T lymphocyte |
Lymphocytes | A type of white blood cell that make antibodies to fight off infections |
Major Histocompatibility Complex (MHC) | "flag" on top of cells; wait for a protein addition to signal if cell is healthy or infected. |
memory cells | General term for lymphocytes that are responsible for immunological memory and protective immunity. |
MHC I | When a healthy cell presents an antigen protein outside the cell to signal it is infected; signals cytotoxic T to destroy |
MHC II | Expressed on the surface of APCs (macrophages, dendritic cells, B cells) and functions by presenting antigen on the outside of the cell signaling that it is foreign in the body. |
Regulatory T cells | may function in preventing autoimmune reactions, also known as suppressor T cells |
T cells | Cells created in the thymus that produce substances that attack infected cells in the body. |
self antigen | An antigen placed on the MHC protein to signal that this is a healthy cell. |
dendritic cells | Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. They act as messengers between the innate and the adaptive immune systems. |
Macrophages | Found within the lymph nodes, they are phagocytes that destroy bacteria, cancer cells, and other foreign matter in the lymphatic stream by engulfing them using phagocytosis. |
mast cells | They serve as a first line of defense against antigens entering the body due to their location in the skin and mucosa |
natural killer cells (NK cells) | effector lymphocytes of the innate immune system that control several types of tumors and microbial infections by limiting their spread and subsequent tissue damage |
Neutrophils | Most common lymphocyte. A type of white blood cell that engulfs invading microbes and contributes to the nonspecific defenses of the body against disease. Cause pus formation. |
Phagocytosis | A type of endocytosis in which a cell engulfs large particles or whole cells |
Endogenous Antigen | foreign antigens that are present inside body cells |
Exogenous Antigen | include toxins and other secretions and components of microbial cell walls, membranes, flagella, and pili |