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Cengage Ch. 14

Study Guide PhT 5 Week 1

QuestionAnswer
Manufacturing of prescription products for resale to pharmacies is regulated by which organization? Food and Drug Administration (FDA)
Which balance is most appropriate for weighing out bulk quantities of products? Counterbalance
What is the sensitivity requirement of Class A balances? 6mg
What is the name of the document that lists all of the ingredients needed for a specific formulation? Master formula sheet
What is the name of the balance that is NOT appropriate for prescription compounding? Counterbalance
Why are balance usually made of a metal such as brass? Brass is a corrosion resistant metal
Which piece of equipment should balance weights be handled with? forceps
What materials are spatulas usually made of? Plastic, stainless steel, or hard rubber
What is another name for compounding slabs? Ointment slabs
What is the type of mortar and pestle that has the advantage of being nonporous and non-staining? glass
Mortars and pestles are usually made of which kind of materials? glass, wedgewood, porcelain
What is the name of the measuring device that is most accurate for volumes greater than 1.5 mL? Cylindrical graduate
What is the advantage of a conical graduate? Easier to clean
What is the smallest size graduate available? 5 mL
When compounding solutions, the drug should be dissolved in what type of solvent? A solvent in which drug is more soluble.
When it is manufactured, which type of mixture must be stirred constantly? Elixir
Why should the compounding of solutions not be rushed? So that proper mixing can occur
When measuring out a liquid in a graduate, the lowest point of the liquid is called what? Meniscus
What is a description of an emulsion? A suspension consisting of two different liquids and an agent that holds them together.
How do compounded solutions and suspensions differ? Suspensions have problematic physical stability once compounded.
Ointments are considered as what type of mixture? Oil-based
Which type of base is used most commonly for rectal suppositories? Cocoa butter
When mixing two or more powders, what should you be sure to do? Triturate them separately to the same particle size.
Which type of base is a water-miscible base often used in vaginal and rectal suppositories? Glycerinated gelatin
What is the largest capsule size that should be given orally to patients? number 0
List 3 ways the sterility of compounded products can be achieved? Filtration, heat, and gas.
When reconstituting dry powders, it is important to know what piece of information? Correct diluent to be used.
What device is used to shrink bands into vials? Heat gun
What material are tablet molds commonly made of? Metal
Which piece of equipment is used to remove seals placed onto vials? Decapper
Which piece of equipment is designed for mixing and melting substances? Beaker
What are the standards of practice used in the pharmaceutical industry and are regulated by the FDA? Good Manufacturing Practices (GMP)
What is the term that is defined as the preparation, mixing, assembling, packing, and labeling of a drug based on the prescription? Extemporaneous compounding
What is the term that is defined as a sweetened liquid containing alcohol and water? Elixir
What is a solid dosage form in which the drug is enclosed within either a hard or soft soluble container? Capsule
Which term is used to describe the action of reducing to a fine powder by friction? Triturate
Which term is used to describe the action of grinding into a smooth substance with moisture? Levigate
What tool is used to provide measurement of volumes of liquids that are less than 1.5 mL? a pipette
What is the term that corresponds with the definition- suspensions made of either small inorganic particles or large organic molecules interpenetrated by a liquid? gel
What is the term that corresponds with the definition- solid, small, and usually cylindrically molded or compressed tablets tablet triturate
What is the term that corresponds with the definition- liquid dosage form in which the active ingredients are dissolved in a liquid vehicle solution
What is the term that corresponds with the definition- liquid substance in which another substance is being dissolved solvent
What is the term that corresponds with the definition- water-based emulsion in which drugs in powder or crystal form are usually mixed in for topical use cream
What is the term that corresponds with the definition- oil-in-water or water-in-oil emulsion characterized by a high content of solids pastes
What is the term that corresponds with the definition- liquid dosage form that contains solid drug particles floating in a liquid medium suspension
What is the term that corresponds with the definition- oil-based emulsion in which drugs in powder or crystal form are usually mixed in for topical use ointment
What is the term that corresponds with the definition- solid device that is used to crush or grind material in a mortar pestle
What is the term that corresponds with the definition- device used for measuring liquids that has a narrow diameter cylindrical graduate
What is the term that corresponds with the definition- two-pan device that may be used to weigh small amounts of drugs (less than 120 g) class A prescription balance
What is the term that corresponds with the definition- device used for measuring liquids that has a wide top and tapers from top to bottom conical graduate
What is the term that corresponds with the definition- device capable of weighing much larger quantities (up to 5 kg) counterbalance
What is the term that corresponds with the definition- long, thin, calibrated hollow tube that is made of glass and is used for measuring liquids pipette
What is the term that corresponds with the definition- cup-shaped vessel in which materials are ground or crushed mortar
What is the term that corresponds with the definition- plate made of ground glass with a hard, flat, and nonabsorbent surface for mixing compounds compounding slab
What is the term that corresponds with the definition- used to transfer solid ingredients to weighing pans and ointment slabs to mix compounds spatula
What are 4 examples of semisolids? Ointment, pastes, creams, and gels
What is the difference between an ointment and cream? Ointments are oil-based (oily), whereas creams are water-based (watery).
 

 



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