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Antituberculosis Med
Stack #35751
Question | Answer |
---|---|
Tb symptoms | weight loss, malaise, fever, cough that is worse in the AM |
Tuberculosis caused by | Mycobacterium tuberculosis |
Transmission | droplets from infected person in the air by cough or sneeze |
Organs affected by Tb | CNS (Meninges), bones and joints, skin, eyes, kidney, ureter, bladder |
Treatment for Tb | 4 drug regimen |
Drugs for Tb | Isoniazid (INH), Rifampin (Rifadin), Ethambutol (Myambutol), Pyrazinamide |
Isoniazid Brand Name | INH |
Rifampin Brand Name | Rifadin |
Ethambutol Brand Name | Myambutol |
Isoniazid M.O.A | inhibits the production of mycolic acid |
Isoniazid M.O.A | inhibits production of mycolic acid |
Isoniazid side effects | fever, rash, CNS disturbances, peripheral neuritis - can be prevented by taking vitamin B6, hepatitis - more common in those over 35 and who drink alcohol |
Rifampin M.O.A | inhibits bacterial enzyme required for RNA synthesis |
Rifampin side effects | GI disturbances, rash, headache, hepatoxicity, flu like syndromewhen not taken regularly |
Ethambutal M.O.A | believed to be inhibition of mycolic acid in cell wall |
Pyrazinmide M.O.A | M.O.A is not well understood |
Ehtambutal side effects | fever, rash, GI disturbances, blurred vision |
Pyrazinamide side effects | most serious: hepatoxicity, hyperurecemia, gout |