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Anemia regen. vs non
Clin Path
Question | Answer |
---|---|
what are the clinical signs of anemia? | pale mucous membranes, exercise intolerance, tachycardia, panting |
subclinical signs? | icterus/jaundice if hemolysis |
syncope means? | fainting spell |
3 basic causes of anemia? | increased loss (hemorrhage), increased destruction (imha or hemolytic anemia), decreased rbc production by bone marrow |
2 types of anemia? | regenerative and non regenerative |
describe regenerative anemia | bone marrow is working, increased production of new rbcs/reticulocytes, indicates blood loss or hemolysis |
describe non regenerative anemia | bone marrow not responding, no or few rbs/reticulocytes, indicates bone marrow defect |
corrected reticulocyte count= | retic count x patient's pcv/normal pcv; cat=37 and dog=45 |
what 2 animals don't have reticulocytes? | horses and cows |
cats have what 2 types of reticulocytes? | punctate and aggregates(you only count these) |
what does nsaids stand for? | nonsteroidal anti-inflammatory drugs |
chronic blood loss over several weeks causes? | iron deficiency |
what is aplastic anemia? | bone marrow failure due to marrow necrosis/inflammation |
what causes aplasitc anemia? | erlichia canis, felv |
what is neoplasia? | crowding of marrow elements w/ neoplastic cells |
what is myelofibrosis? | hypoplasia of marrow elements w/ replacement by collagen |
what is osteopetrosis? | inherited disorder w/ increased bone density |
what happens in hemolytic anemia and what causes it? | rbcs are destroyed; toxins: onion and zinc |
describe imha | antibodies directed against rbc membrane antigens develop and ab-coated rbcs are removed from circulation by spleen |
imha is more common in which gender? | females |
imha is what in cats? | rare |
primary imha is? | idiopathic |
secondary imha is? | initiated by a trigger |
how do we diagnosis it? | regeneration (a lot of reticulocytes), spherocytes |
what is the treatment for imha? | corticosteriods- high doses of prednisone, azathioprine |
what is eia/swamp fever? | contagious and potentially fatal viral disease in horses |
which tests checks for antibodies to the virus? | coggins |