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RESPIRATORY DRUGS
Question | Answer |
---|---|
these drugs bind to receptors in the lungs | Beta 2 adrenergic agonists |
beta 2 adrenergic drug that is used for acute asthma attacks | Albuterol |
beta 2 adrenergic drug that is used long-term and for the prevention of asthma attacks | Salmeterol |
Side effects of beta 2 adrenergic agonists (4) | nervousness, tremors, possible chest pain, palpitations |
beta 2 adrenergic drug used for short-term | albuterol |
TRUE / FALSE Beta 2 adrenergic agonists can be used with glucocorticoids or anticholinergics | TRUE |
TRUE / FALSE Beta 2 adrenergic agonists should not be used with glucocorticoids or anticholinergics due to its antagonistic effects | FALSE Beta 2 adrenergic agonists can be used with glucocorticoids or anticholinergics |
What is the therapeutic level of Theophylline? | 10 - 20 mcg/mL |
TRUE/ FALSE Xanthines can be used for asthma but not for COPD | FALSE Xanthines can be used for long-term control of asthma or COPD |
MOA: increase cAMP which leads to bronchodilation A. Anticholinergics B. Decongestants C. Xanthines | C. Xanthines |
Side effects of Xanthines (5) | GI upset, nervousness, headache, risk for dysrhythmias and seizures |
Albuterol and Salmeterol are what type of bronchodilators? A. Beta 2 adrenergic Agonists B. Xanthines C. Anticholinergics | A. Beta 2 adrenergic agonists |
What type of bronchodilator is Theophylline? | Xanthines |
What type of bronchodilator is Ipratropium? | Anticholinergics |
This drug is used for long-term control of asthma and COPD | Xanthines (Theophylline) |
This drug/s is/are used for COPD, rhinitis, and asthma (off-label use) | Anticholinergics (Ipratropium) |
MOA: blocks acetylcholine receptors in airway's smooth muscle | Anticholinergics |
Side effects of anticholinergics (4) | dry mouth, bitter taste, throat/ nasal irritation |
Side effects: dry mouth, bitter taste, throat/ nasal irritation | Anticholinergics |
Patient teaching for anticholinergics | increased fluid intake and suck on candy |
Side effects: GI upset, nervousness, headache, risk for dysrhythmias and seizures | Xanthines (Theophylline) |
Side effects: nervousness, tremors, possible chest pain, palpitations | Beta 2 adrenergic agonists |
What type of drug are Beclomethasone and Momethasone? | Corticosteroids |
What type of drug are Budesonide and Fluticasone? | Corticosteroids |
Drug used for asthma and rhinitis | Corticosteroids |
Side effects of corticosteroids (3) | headache, sore throat, possible fungal infection (candidiasis) |
Which comes first? Bronchodilators or corticosteroids? | bronchodilators then wait for 5 minutes before administering corticosteroids |
What type of drugs are Montelukast and Zafirlukast? | Leukotriene Receptor Antagonists |
This type of drug is used for asthma and exercise-induced bronchoconstriction | Leukotriene receptor antagonists |
MOA: decrease effect of leukotrienes to decrease inflammation and dilate the airways | Leukotriene receptor antagonists |
Side effects of Zafirlukast? (2) | headache, increased liver enzymes |
When to administer Montelukast? | at night and before exercise |
When to administer Zafirlukast? | before meals or on an empty stomach |
What type of drug are Benzonatate, Codeine and Dextromethorphan? | Antitussives |
mainly used for cough | Antitussives |
MOA: anesthetic effects on vagal nerve receptors in airways A. Benzonatate B. Dextromethorphan C. Codeine | A. Benzonatate |
MOA: binds to opioid receptors in CNS and decrease cough reflex A. Benzonatate B. Dextromethorphan C. Codeine | C. Codeine |
MOA: suppress cough reflex in the medulla A. Benzonatate B. Dextromethorphan C. Codeine | B. Dextromethorphan |
Side effects: sedation, constipation, GI upset A. Benzonatate B. Dextromethorphan C. Codeine | A. Benzonatate |
Side effects: sedation, respiratory depression, constipation, GI upset A. Benzonatate B. Dextromethorphan C. Codeine | C. Codeine |
Side effects: dizziness, possible sedation at increased doses A. Benzonatate B. Dextromethorphan C. Codeine | B. Dextromethorphan |
Side effects of Benzonatate (3) | Side effects: sedation, constipation, GI upset |
Side effects of Codeine (4) | Side effects: sedation, respiratory depression, constipation, GI upset |
Side effects of Dextromethorphan (2) | Side effects: dizziness, possible sedation at increased doses |
What type of drug is Guaifenesin? A. Mucolytics B. Anticholinergics C. Expectorants D. Antitussive | C. Expectorants |
Used for: non-productive cough associated with respiratory infections | Expectorants |
MOA: lessens viscosity of secretions which makes cough more productive | Expectorants |
Side effects of Expectorants (2) | GI upset, dizziness |
What type of drug is Acetylcysteine? A. Mucolytics B Expectorants C. Antihistamine D. Decongestants | A. Mucolytics |
Used for: pulmonary disorders with thick mucus secretions A. Decongestants B Expectorants C. Antihistamine D. Mucolytics | D. Mucolytics (Acetylcysteine) |
Antidote for acetaminophen overdose | Acetylcysteine |
Side effects of Mucolytics (Acetylcysteine) (4) | bronchospasm, nausea, vomiting, rash |
this drug smells like rotten eggs | Acetylcysteine |
What type of drug are pseudoephedrine and phenylephrine? A. Mucolytics B Expectorants C. Antihistamine D. Decongestants | D. Decongestants |
MOA: vasoconstriction of respiratory tract mucosa | Decongestants |
Side effects of Decongestants (5) | nervousness, palpitations, weakness, insomnia, possible rebound congestion |
What type of drug is diphenhydramine? A. Mucolytics B. Antihistamine C. Expectorants D. Decongestants | B. Antihistamine (1st generation) |
What type of drug are Loratadine and Cetirizine? A. Mucolytics B. Antihistamine C. Expectorants D. Decongestants | B. Antihistamine (2nd generation) |
Used for: allergy symptoms (such as rhinitis, itchy watery eyes, sneezing), motion sickness, urticaria (hives) | Antihistamine |
MOA: block H1 receptors A. Antitussives B. Antihistamine C. Leukotriene Receptor Antagonists D. Beta 2 Adrenergic Agonists | B. Antihistamine |
Side effects of antihistamine (more of 1st gen) 3 main | sedation, anticholinergics side effects (dry mouth, constipation, urinary retention), photosensitivity remember: can't see, pee, poop, spit |
Side effects: GI upset, dizziness A. Decongestants B. Mucolytics C. Antihistamines D. Expectorants | D. Expectorants |
Side effects: bronchospasm, nausea, vomiting, rash A. Mucolytics B. Decongestants C. Antihistamines D. Expectorants | A. Mucolytics |
Side effects: nervousness, palpitations, weakness, insomnia, possible rebound congestion A. Mucolytics B. Expectorants C. Decongestants D. Antihistamines | C. Decongestants |
Side effects: sedation, anticholinergics side effects (dry mouth, constipation, urinary retention), photosensitivity A. Mucolytics B. Expectorants C. Decongestants D. Antihistamines | D. Antihistamine (1st generation) |
Which of the following is an Anticholinergic? A. Ipratropium B. Fluticasone C. Guaifenesin D. Phenylephrine | A. Ipratropium |
Which of the following is best used for acute asthma attacks? A. Phenylephrine B. Acetylcysteine C. Albuterol D. Salmeterol | C. Albuterol |
What drug is given for long-term use |