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Neuro and Psych 4
BDK
generic | brand | pharmacologic category | common indication | essential knowledge |
---|---|---|---|---|
carbamazepine (PO) | tegretol | anticonvulsant | seizure disorders, bipolar disorder | Key Side Effects: dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia US Boxed Warnings: risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agr |
Lamotrigine (PO) | Lamictal | anticonvulsant | seizure disorders, bipolar disorder | Key Side Effects: nausea, vomiting, somnolence, skin rash US Boxed Warnings: risk of serious dermatologic reactions, including SJS |
divalproex (valproic acid derivative) (po) | depakote, depakote ER, Depakene | anticonvulsant | seizure disorders, bipolar disorder, migraine prophylaxis | Key Side Effects: drowsiness, weight gain, tremor, hair loss, thrombocytopenia US Boxed Warnings: may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity |
Topiramate (PO) | Topamax | anticonvulsant | seizure disorder, migraine prophylaxis | Key Side Effects: drowsiness, weight gain, tremor, hair loss, thrombocytopenia US Boxed Warnings: may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity |
Levetiracetam (PO, IV ) | Keppra | anticonvulsant | seizure disorders | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness |
Oxcarbazepine (PO) | Trileptal | anticonvulsant | seizure disorders | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness |
Phenobarbital (PO, IM, IV) | ----- | anticonvulsant | seizure disorders | Key Side Effects: somnolence, dizziness, risk of SJS phenytoin |
Phenytoin (PO, IV) | Dilantin | anticonvulsant | seizure disorders | Key Side Effects: somnolence, dizziness, gingival hyperplasia, hirsutism, risk of SJS US Boxed Warning: cardiovascular risk with rapid infusion Other Notes: narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; |
Gabapentin (PO) | Neurontin | anticonvulsant | seizure disorder, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision |
Pregabalin (PO) | Lyrica | anticonvulsant | seizure disorder, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision |